INIBIOLP 05426
INSTITUTO DE INVESTIGACIONES BIOQUIMICAS DE LA PLATA "PROF. DR. RODOLFO R. BRENNER"
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
A hippocampal age-related eleven gene signature conserved across the species
Autor/es:
ABBA, MARTIN C.; MOREL GR; LACUNZA, EZEQUIEL; OUTEIRO TF; PARDO J; FRANCELLE, LAETITIA; GOYA RG
Reunión:
Congreso; Society for Neuroscience Meeting 2018; 2018
Resumen:
Even though some descriptive studies on transcriptomics have been conducted on the rodent senile hippocampus, most of them were on males. Here, we studied age changes in learning and memory, hippocampal morphology and transcriptome in female rats. In the Barnes Maze Task, senile rats displayed significant deficits in the learning parameters latency (two-way RM ANOVA age factor P=0.044) and errors (two-way RM ANOVA age factor P
