1H NMR characterization of the intermediate formed upon UV-A excitation of biopterin, neopterin and 6-hydroxymethylpterin in O2-free aqueous solutions

MARIANA VIGNONI; M. LAURA SALUM; ROSA ERRA-BALSELLS; ANDRÉS H. THOMAS; FRANCO M. CABRERIZO

CHEMICAL PHYSICS LETTERS

ELSEVIER SCIENCE BV

Año: 2010 vol. 484 p. 330 - 332

0009-2614

Pterins belong to a family of heterocyclic compounds present in a wide range of living systems and participate in relevant biological functions. Under anaerobic conditions, the unstable red intermediate generated by UV-A irradiation of biopterin, neopterin and 6-hydroxymethylpterin was identified by 1H NMR analysis, in alkaline D2O solutions, as 5,8-dihydro-6-formylpterin. analysis, in alkaline D2O solutions, as 5,8-dihydro-6-formylpterin. analysis, in alkaline D2O solutions, as 5,8-dihydro-6-formylpterin. analysis, in alkaline D2O solutions, as 5,8-dihydro-6-formylpterin. analysis, in alkaline D2O solutions, as 5,8-dihydro-6-formylpterin. 1H NMR analysis, in alkaline D2O solutions, as 5,8-dihydro-6-formylpterin.2O solutions, as 5,8-dihydro-6-formylpterin.