CINDECA   05422
CENTRO DE INVESTIGACION Y DESARROLLO EN CIENCIAS APLICADAS "DR. JORGE J. RONCO"
Unidad Ejecutora - UE
artículos
Título:
Synthesis of substituted flavones and chromones using a Well-Dawson heteropoliacid as catalyst
Autor/es:
D. BENNARDI, G. ROMANELLI, J. JIOS, J. AUTINO, G. BARONETTI, H. THOMAS
Revista:
Arkivoc
Editorial:
ARKAT USA, Inc.
Referencias:
Año: 2008 vol. XI p. 123 - 123
ISSN:
1424-6376
Resumen:
In this work, we report the use of bulk and silica-supported Wells-Dawson acid(H2P2W18O62.24H2O) as reusable, heterogeneous catalysts to obtain substituted flavones andchromones for the cyclization of 1-(2-hydroxyphenyl)-3-aryl-1,3-propanediones. The reactionexperiments were performed using toluene as solvent at reflux and in the absence of solvent, at110 °C. Under these conditions eleven examples were obtained with very good yields (82-91%)and high selectivity. The catalysts were easily recycled and reused without loss of their catalyticactivity. The presented synthetic method is a simple, clean and environmentally friendlyalternative for synthesizing substituted flavones and chromones.2P2W18O62.24H2O) as reusable, heterogeneous catalysts to obtain substituted flavones andchromones for the cyclization of 1-(2-hydroxyphenyl)-3-aryl-1,3-propanediones. The reactionexperiments were performed using toluene as solvent at reflux and in the absence of solvent, at110 °C. Under these conditions eleven examples were obtained with very good yields (82-91%)and high selectivity. The catalysts were easily recycled and reused without loss of their catalyticactivity. The presented synthetic method is a simple, clean and environmentally friendlyalternative for synthesizing substituted flavones and chromones.
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