Insulin Regimen in Adults With Type 1 Diabetes in Latin America: Results From the International Diabetes Management Practices Survey (IDMPS).

LAVALLE GONZÁLEZ; GAGLIARDINO JJ ET AL.

Philadelpia

Congreso; American Diabetes Association’s 72nd Scientific Sessions; 2012

American Diabetes Association

IDMPS is an ongoing 5-year multinational observational study documenting the current quality of care provided to people with type 1 or type 2 diabetes. Feasibility analyses were previously performed to validate the chances 01 pooling the data collected during 2005 and 2009 in Latin America. The aim was to identify patient profiles associated with insulin regimen in type 1 diabetes mellitus (T1DM) patients in Latin America. Patient profiles of 2693 patients were determined using logistic regression analysis. The most common insulin regimen was basal-prandial therapy (65.4%), followed by basal therapy alone (23.7%), and other regimens (10.9%1. The use of basal-prandial therapy increased steadily from the first to the fourth survey (59.5% to 73.9%) with a mean duration of treatment of 13.8 ± 10.9 years. The majority of the patients used insulin pens (56.0%) and 47.6% used vials and syringes. The number of insulin injections/day was 4.2 ± 1.0, and 92.9% of these patients received 3 to 6 injections/day. Basal and prandial daily doses were 0.51 ± 0.23 and 0.23 ± 0.17 IU/kg, respectively. Of the patients on basal-prandial insulin therapy 52.4% were treated with insulin analog and 47.6% with regular insulin. Basal-prandial insulin therapy was significantly associated with age (< 40 vs > 65 years; OR = 2.3, p= 0.003), time since diagnosis (OR = 0.7 lar 5-year changes, P< 0.001), time on insulin treatment (OR = 1.5 for 5-year changes, P< 0.001), glucometer use (0R = 1.8, P= 0.012), self-management (self-monitoring blood glucose and insulin self-adjustment); (0R =3.5, P< 0.001), total daily dose (0R = 1.3 for changes 01 0.1 UI/kg, P< 0.001) and patient recruited by specialists (OR = 1.6, P= 0.009). The increase in use of the basal-prandial insulin regimen in T1DM patients was strongly associated with self-management performance in Latin America during 2005 and 2009. Therefore the promotion of self-care would improve compliance with this insulin regimen.