RALF4/19 peptides interact with LRX proteins to control pollen tube growth in Arabidopsis

MUSCHIETTI, JORGE P.; MARTÍNEZ-BERNARDINI, ANDREA; RINGLI, CHRISTOPH; SOMOZA, SOFÍA C.; GAGLIARDINI, VALERIA; MECCHIA, MARTIN A.; DUSS, NADINE N.; GROSSNIKLAUS, UELI; FABRICE, TOHNYUI NDINYANKA; BOISSON-DERNIER, AURÉLIEN; SANTOS-FERNANDEZ, GORKA

SCIENCE

AMER ASSOC ADVANCEMENT SCIENCE

Año: 2017 vol. 358 p. 1600 - 1603

0036-8075

The communication of changes in the extracellularmatrix to the interior of the cell is crucial for a cell´s function.The extracellular peptides of the RAPID ALKALINIZATION FACTOR (RALF) family have been identified as ligands of receptor-like kinases of the CrRLK1L subclass, but the exact mechanism of their perception is unclear.We found that Arabidopsis RALF4 and RALF19 redundantly regulate pollen tube integrity and growth, and that their function depends on pollen-expressed proteins of the LEUCINE-RICH REPEAT EXTENSIN (LRX) family, which play a role in cell wall development but whose mode of action is not understood.The LRX proteins interact with RALFs, monitoring cell wall changes, which are communicated to the interior of the pollen tube via the CrRLK1L pathway to sustain normal growth.