INGEBI 02650
INSTITUTO DE INVESTIGACIONES EN INGENIERIA GENETICA Y BIOLOGIA MOLECULAR "DR. HECTOR N TORRES"
Unidad Ejecutora - UE
artículos
Título:
A Latin American perspective on ion channels
Autor/es:
BARAJAS-LÓPEZ, CARLOS; ELGOYHEN, ANA BELÉN
Revista:
MOLECULAR PHARMACOLOGY
Editorial:
AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS
Referencias:
Año: 2016 vol. 90 p. 286 - 287
ISSN:
0026-895X
Resumen:
Ion channels, both ligand- And voltage-gated, play fundamental roles in many physiologic processes. Alteration in ion channel function underlies numerous pathologies, including hypertension, diabetes, chronic pain, epilepsy, certain cancers, and neuromuscular diseases. In addition, an increasing number of inherited and de novo ion channel mutations have been shown to contribute to disease states. Ion channels are thus a major class of pharmacotherapeutic targets.
