INGEBI 02650
INSTITUTO DE INVESTIGACIONES EN INGENIERIA GENETICA Y BIOLOGIA MOLECULAR "DR. HECTOR N TORRES"
Unidad Ejecutora - UE
artículos
Título:
Microbial hydrolysis of acetylated nucleosides.
Autor/es:
JULIETA PANERO, JORGE TRELLES, VALERIA RODANO, JAVIER M. MONTSERRAT, LUIS E. IGLESIAS, ELIZABETH LEWKOWICZ
Revista:
BIOTECHNOLOGY LETTERS
Editorial:
Springer
Referencias:
Lugar: Netherlands; Año: 2006 vol. 28 p. 1077 - 1081
ISSN:
0141-5492
Resumen:
Enzymatic hydrolysis of acetylated nucleosides using microbial whole cells has been carried out for the first time. Unlike Candida antarctica B lipase-catalysed alcoholysis, none of the tested microorganisms displayed a common deacetylation profile. Depending on the substrate and the biocatalyst used, 5¢-selective deprotectionor mixtures of mono O-acetylated products were obtained.
