Synthesis of Latex-Protein Complexes for Immunoassays

GONZALEZ, V.D.; GARCÍA, V.; VEGA, J.R.; MARCIPAR, I.; MEIRA, G.R.; GUGLIOTTA, L.M.

Córdoba

Simposio; V Simposio Argentino – Chileno de Polímeros - ARCHIPOL ‘09; 2009

Immunodiagnosis latex-protein complexes are useful for detecting pregnancies, rheumatoid arthritis, toxoplasmosis, malaria, brucelosis, and leptospirosis. Immunodiagnosis tests involve specific reactions between an antigen (or antibody) contained in a human fluid and an antibody (or antigen) contained in the latex-protein complex. The particles agglutination process can be visualized either directly or via instrumental methods. With the final aim of producing an immunodiagnosis kit for the Chagas disease, the present work describes the sensitization of base latexes with 3 antigenic proteins of Trypanosoma cruzi.