INVESTIGADORES
REPETTO Marisa Gabriela
congresos y reuniones científicas
Título:
Free radicals and antioxidant defenses in Grave?s disease.
Autor/es:
ABALOVICH, MARCOS; BEQUELMAN DIANA; REIDES, CLAUDIA; REPETTO, MARISA; LLESUY, SUSANA; GUTIERREZ, SILVIA; GUITELMAN, ALICIA
Lugar:
Toronto
Reunión:
Congreso; 11 th Congreso international Thyroid Congress; 1995
Institución organizadora:
Sociedad Argentina de Endrocrinología.
Resumen:
It has been described a decrease of some antioxidant compounds in patients suffering hypertyroidism. The aim of this work was to evaluate the participation of free radicals in active Grave´s disease evaluating the antioxidant/prooxidant balance. We studied 12 hyperthyroid patients (9 female and 3 male) of x= 34 years old, T3= 446 ± 59 ng%; T4= 19 ± 1 ìg%; anti TSH receptor antibodies= 32 ± 6 %; Intake of I131= 59 ± 6 %; coursing x= 8.3 months of evolution. The parameters evaluated were: 1) Tert-Butyl hydroperoxide intiated chemiluminescense (Ql), 2) superoxide dismutase (SOD) and catalase (CAT), 3) glutathione (GSH) and total plasma antioxidant capacity (TRAP). 10 normal adults were taken as controls (C). Results: Levels of Ql were higher (p
