First detection of porcine circovirus type 3 (PCV3) associated with reproductive disorders in a farm in Argentina

SERENA MS; BARRALES H; LOZADA MI; METZ G; ASPITIA C; GILEAD T; QUIROGA MA; PERFUMO CJ; PIÑEYRO, P; ECHEVERRÍA MG

Rio de Janeiro

Congreso; IPVS 2020; 2020

Since 2015 a new circovirus, namely porcine circovirustype 3 (PCV3), suddenly appears within the broad field ofemerging swine viruses through metagenomic sequencingstudies (4, 5). It belonged from an outbreak of dermatitisand nephropathy-like syndrome (PDNS) in sowsassociated with reproductive failure -mommies, abortionand stillbirth- (4). Thereafter, PCV3 infection has beeninvolved in cardiac and multisystemic inflammation inmummies as well as in others pigs ages (3, 5).. The PCV3genome is circular single-stranded DNA with a size of2000 nt containing two major open reading frames(ORFs), similar as PCV2. ORF 1 encodes the replicationassociated protein (Rep) that plays roles in virusreplication. ORF2 encodes the capsid (Cap) protein of thevirus. PCV3 co-infections with PRRSV, PCV2, TTSuV1,TTSuV2, PPV2, PPV6, and PPV7 has been reported (2).This report describes the etiological, clinical andpathological features of chronic reproductive disorders ina herd in Argentina from which PCV3 and parvovirustype 1 was identified.