On the Precision Limits for Estimating Restriction Lengths in Diffusion Magnetic Resonance Imaging

ANALIA ZWICK

Buenos Aires

Seminario; Humboldt Colloquium "Shaping the Future of German-Argentinian Scientific Cooperation: The Role of Curiosity-Driven Research"; 2018

Alexander von Humboldt Fundation

Diffusion weighted imaging in Magnetic Resonance (MRI) is a powerful non-invasive technique for microstructure characterization. However, attaining microstructure resolution is still a challenge as the MRI resolution is much larger. Resorting to tools from quantum information theory, we analytically derive the ultimate precision limits for estimating microstructure sizes as the one given by restriction lengths in diffusion processes with diffusion weighted MRI sequences. We provide the control conditions, exemplifying with routinely gradient waveforms and with generic geometries of the microstructures, to achieve this precision limit in the estimation considering limitations imposed by T2 relaxation.