STUDY OF THE IMMUNE RESPONSE ASSOCIATED WITH GENITAL INFECTIONS AND ITS RELATIONSHIP WITH INFERTILITY

ROMINA CECILIA RUSSI; PAULA JULIETA CEPEDA; MARÍA INÉS GARCÍA; CAROLINA VEAUTE

Buenos Aires

Congreso; Reunión Conjunta de Sociedades de Biociencias 2017; 2017

Sociedad Argentina de Inmunología

Chlamydia trachomatis (Ct), Mycoplasma hominis (Mh) andUreaplasma urealyticum (Uu) are usually associated with infertility.Our aim was to study immunological factors induced by genitalinfections as a potential cause of infertility. Antisperm antibodies(ASA) were analyzed by ELISA and cytokines and master transcriptionfactor expression were quantified by RT-qPCR using the ΔΔCtcomparative method. Sperm parameters were analyzed by WHOrecommendations. Vaginal washing were collected from 59 females,Infertile With Infection (IWI-f), Infertile Without Infection (IWoI-f), FertileWithout Infection (FWoI-f) and semen from 27 Infertile male With(IWI-m) and Without infection (IWoI-m). Categorical variables wereanalyzed by Fisher?s Exact test, P