CAPN1 haplotypes in beef cattle: implications for improving tenderness in Braford

IGLESIAS, P.P.; CAFFARO, M.E.; AMADIO, A.F.; ARIAS MAÑOTTI, A.; POLI, M.A.

Congreso; V Congreso Mundial Braford; 2012

The purpose ofthis work is to explore the variability and frequencies of CAPN1 haplotypes in a herd of Braford cattle (3/8 Brahman5/8Hereford) as a first step to characterize common haplotypes and to evaluate ifthere is enough variation to enable tenderness improvement. Also, we comparethis information with haplotype data from two herds of Hereford and Brahmancattle in order to find a shared pattern between common haplotypes and thetrend for Bos taurus cattle toproduce tender meat than Bos indicus.Finally, we test the ability of a new InDel polymorphism to further subdividethe tender haplotypes previously reported in order to generate more classeswith phenotypic effects in future association studies. Haplotype reconstructionwas carrying out using pedigree information and both single nucleotidepolymorphism (SNP) and insertion-deletion polymorphism (InDel) genotypes. Ourfindings suggest a shared pattern between tenderness variation among breeds andtheir common haplotypes. Braford herd showed high level of haplotypevariability as well as of haplotypes that indicate a more tender meat. Theselective pressures on Braford tropical adapted cattle towards weight gainwithout losing adaptability had no apparent effects on CAPN1 genetic diversity. These evidence highlights the great potentialof braford breed of be genetically improved for tenderness.