Characterization of antioxidant activity or aqueous extracts from Ginkgo Biloba

PEVERINI AGUSTINA; REIDES CLAUDIA; HVOZDA ARANA AILEN; JANEZIC NATASHA; LASAGNI VITAR ROMINA; FERREIRA SANDRA MARIA; LLESUY SUSANA

Mar del Plata

Congreso; LXI Reunion Cientifica Anual de la SAIC; 2016

Sociedad Argentina de Investigación Clínica

Growing interest in natural antioxidants has developed due to a need for more effective, less toxic and cost effective antioxidants, and medicinal plants appear to have these desired advantages. Ginkgo biloba extract has been claimed effective in a variety of disorders associated with neurodegeneration like Parkinson, dementia, Alzheimer and glaucoma. The aims of this work were to evaluate the antioxidant capacity and the effect on lipid-peroxidation of aqueous extracts from Ginkgo biloba. Infusion and decoction of 5 % w/v were prepared and brain homogenates were used to determine the effect on lipid peroxidation. Antioxidant activity was assessed by 1,1-diphenyl-2-picrylhydrazyl radical (DPPH), and 2,20-azino-bis(3-ethylbenzthiazoline)-6-sulfonic acid radical (ABTS) scavenging activity. Decoction displayed significant higher values than infusion in terms of DPPH (p