Theoretical and experimental study of 1-[(arylcarbamate)- pentyl]-1,2,3,4- tetrahydroisoquinoline derivatives acting as highly selective ligands of the D2 dopamine receptor.

M. LUCRECIA BOGADO; OSCAR PARRAVICINI; SEBASTIAN ROJAS; EMILIO L. ANGELINA; SEBASTIAN A. ANDUJAR; ENRIZ, RICARDO D.

Congreso; 42nd International Congress of Theoretical Chemists of Latin Expression; 2016

The critical importance of both D1 and D2 receptors of dopamine signaling in Central Nervous System function makes it highly desirable to gain detailed knowledge about the structural features necessary for full agonist activity and selectivity at these receptors