INVESTIGADORES
PIRO Oscar Enrique
congresos y reuniones científicas
Título:
Azilsartan and its Zn(II) complex. Synthesis, anticancer mechanism of action and interaction with bovine serum albumin
Autor/es:
V. MARTINEZ; J. S. TODARO; M. V. AGUIRRE; O. E. PIRO; G. A. ECHEVERRÍA; E. FERRER; P. A. M, WILLIAMS
Lugar:
Buenos Aires
Reunión:
Congreso; Segunda Reunión Conjunta de Sociedades de BioCiencias; 2017
Institución organizadora:
Sociedades de BioCiencias
Resumen:
Azilsartan is the eighth approved member of angiotensin II receptor blockers for hypertension treatment. Considering that some drugs have additional beneficial effects on health when administered, we studied its effects and mechanisms of action on a human lung cancer cell line A549. We have also modified the structure of the drug by complexation with Zn(II) cation and determined the anticancer effect.
