Effect of Ilex paraguariensis (Mate) aqueous extracts and chlorogenic acid on the antioxidant enzymes (SOD, CAT and Px) in rat submandibulary glands

MARTINO RENZO; COGOI LAURA; ANESINI CLAUDIA; FILIP ROSANA

Congreso; 12th World Congress on Scientific Program ALTERNATIVE MEDICINE; 2018

Ilexparaguariensis(Mate tree) is a plant cultivated in South America. It is industrialized toobtain the "yerba mate" product, consumed in the region as a tea-likebeverage. The mate-drinking habit has been popular for centuries, and wasadopted from the native inhabitants of the region (Guaraníes). Argentina is themain producer country. This species is worldwide recognized for itsnutritional, functional and medicinal properties  and exported to over 40 countries. Among thebioactive compounds present, polyphenols like chlorogenic acid (CL) havedemonstrated antioxidant activity.Reactivespecies of oxygen (ROS) are well known inducers of cellular and tissuepathogenesis leading to numerous disorders including periodontal disease.Antioxidant enzymes such as superoxide dismutase (SOD), peroxidase (Px) andcatalase (CAT), play a protector role in mouth oxidative physiological andpathological process such as inflammation, infections and cancer. Previousreports indicated that aqueous extracts of I. paraguariensis (AE)exerted a positive effect on the human oral health. The objective of this workwas to determine in vitro, the effect of AE and CL upon SOD, CAT and Pxsecretion, using a rat submandibulary glands model.