Alteration in the Expression Insulin-Like Growth Factor-II (IGF-II) Family Members in Bovine Cystic Ovarian Disease

REY, F; RODRIGUEZ, MF; SALVETTI, NR; PALOMAR, MM; BARBEITO, CG; ORTEGA, HH

Pittsburgh, Pennsylvania

Congreso; 42nd Annual Meeting, Society for the Study of Reproduction (SSR); 2009

Society for the Study of Reproduction (SSR),

Cystic ovarian disease (COD) is one of the most common reproductive disorders in cattle, and the mechanism leading to their development was proposed to be of multifactorial etiology. Although it is widely accepted that a neuroendocrinological dysfunction of the hypothalamic-pituitary-gonadal axis is an important etiological factor, several reports have discussed the association between COD and growth factors in different species. Our hypothesis states that variations in members of the IGF superfamily are involved in follicular cyst development.