CONICET | Buscador de Institutos y Recursos Humanos

Osteoporosis, osteopenia and periodontal disease have in common several risk factors, among them hyperthyroidism and smoking habits. There is scarce information in the literature about the association between periodontal disease and osteoporosis and/or osteopenia. Some works suggest that osteoporotic women are propend to a higher loss of periodontal insertion, alveolar bones, and teeth. Since osteoporosis and osteopenia produce similar alterations to bone density and metabolism than periodontal disease, elemental analysis of the mineral content of oral fluids (i.e. saliva and gingival crevice fluid) could establish a correlation with the severity of those pathologies. Thirty adult women coming from a gynecologic service were studied. All he patients were coursing post-menopause; some of them were healthy (control group) and the others were undergoing some stage of osteoporosis or osteopenia. They were systemic healthy, non smoker, with no dental implants, and suffering certain degree of periodontal disease (CPI>1). Samples of saliva and gingival crevice fluid were extracted with micro-capillaries and deposited on Si reflectors. Known amounts of Ga were added to the samples in order to act as internal standard. The samples were analyzed by TXRF using beam guides. The spectrometer consists of a 3 kW x-ray tube with a Mo target, an angular sample stage to align the beam guides, an 8K multichannel analyzer. The spectra were analyzed with standard programs for spectrum analysis. Elemental concentrations of several elements, from P to Zn, were determined. The concentration of some elements in saliva showed different behavior as compared to gingival crevice fluid. Possible correlations among concentrations, the degree of periodontal disease, and the severity of osteopenia/osteoporosis illness are suggested.

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