INVESTIGADORES
FERESIN Gabriela Egly
congresos y reuniones científicas
Título:
NITRIC OXIDE SYNTHASE (NOS) EXPRESSION IN THE HIPPOCAMPUS FROM THE PROGENY OF EXPERIMENTAL DIABETES MOTHERS. EFFECT OF THE INTAKE OF VEGETABLE OILS
Autor/es:
MAGRINI HUAMAN RN; REY M; COIRINI E; DELGADO JF; VEGA MC; IGHANI M; TAPIA A; FERESIN GE; COIRINI H
Lugar:
Buenos Aires
Reunión:
Jornada; XVIII Jornadas Anuales Multidisciplinarias; 2016
Institución organizadora:
SOCIEDAD ARGENTINA DE BIOLOGIA
Resumen:
Uncontrolled maternal hyperglycemia during pregnancy produces alterations in thedeveloping nervous system of the offspring. In previous studies, we showed that pistachio oil (PS) increases exploratory activity in the open field test. The aim of this study was to:1) Evaluate the expression of hippocampal NOS in adult rats (SD, male/female, 8 months old) born from control mothers (CO) or mothers with experimental diabetes (streptozotocin, 30 mg /Kg iv; DO) and 2) Study the effect of early dietary supplementation with corn oil (MZ), extra virgin olive oil (OL) and PS. The oils were administered from day 2 to 62 of age (8μl /15g). NOS expression was analyzed by western blot. In males NOS level was ignificantly higher in the DO than in CO (ANOVA, p
