EFFECTS OF NATIVE PLANTS DECOCTION FROM CUYO ON SERUM PARAMETERS OF RATS WITH EXPERIMENTAL DIABETES

REY M; MAGRINI HUAMÁN RN; DELGADO JF; TAPIA A.; FERESIN GE; COIRINI H

Buenos Aires

Jornada; XVIII Jornadas Anuales Multidisciplinarias; 2016

Sociedad Argentina de Biología

Diabetes mellitus is a chronic disease with great global distribution, thus the search of new therapeutic alternatives is constant. Several studies indicate that 85% of world population still uses ?medicinal plants? to be healthy. In particular, in the region of Cuyo (Argentine), Oxalis erythrorhiza (Oe) and Tessaria absinthiodes (Ta) species are consumed to regulate the glycaemia (Glu) and the cholesterol level (Chol), although those effects lack of scientific support. Male rats (SD) of 42 days, controls (C, i.p. vehicle) or with experimental diabetes (D, i.p. streptozotocin 30mg/Kg) received 10% decoctions of Oe (DOe and COe), Ta (DTa and CTa), or water (DW and CW) like only drink for 4 weeks. Glu, Chol and triglycerides (TG) were determined on samples obtained weekly with colorimetric kits. At the end of the treatment, Glu and TG were higher in the D than the C (200% and 170% respectively; p