Neutrophils recruitment modulates T cell response in lymph nodes

CASTELL SD; HARMAN MF; GORLINO CV; MORÓN G; MALETTO BA; PISTORESI-PALENCIA MC

Buenos Aires

Congreso; II French-Argentine Immunology Congress y LXIII Reunión Anual de la Sociedad Argentina de Inmunología; 2015

SAI

Abstract: Previously we demonstrated that when mice were immunized with OVA emulsified in Freund?s complete adjuvant on day 0, boosted with OVA emulsified in Freund?s incomplete adjuvant on day 15, and 10 days after injected with OVA-FITC in the footpad, the main OVA-FITC+ cells recruited in draining popliteal lymph nodes (D-poLNs) were neutrophils whereas these cells were undetectable on control popliteal lymph nodes (ND-poLNs) corresponding to the footpad injected with saline solution (D-poLNs 9,9±2% vs. ND-poLNs 0,3±0,1%; p