EMBRYONIC DEATH IN A MOUSE MODEL. OF BOVINE TRITRICOMONOSIS. RELATION WITH THE ENDOMETRIAL

WOUDWYK M, BARBEITO C, CACCIATO C, SOTO P, GIMENO E, MONTEAVARO C.

Huerta Grande. Córdoba

Congreso; I Reunión Conjunta de Sociedades de Biología de la República Argentina. Huerta Grande. Córdoba. Agosto 2007; 2007

Sociedades de Biología de la República Argentina

In a previous work we demonstrate that in a model in mouse BALB/ C of bovine tritricomonosis the embryonic death takes place during the second quarter of the gestation. In the present work the endometrial alterations are analyzed in mice with 5-10 days of pregnancy infected by Tritrichomonas foetus. The uterine horns were tried for its coloration with HE, Giemsa, Toluidina’s Blue and for the histochemistry tecniques of PAS and TUNNEL. Some animals already lost its pregnancy in the day 6. In most cases the animals of more than 8 days of pregnancy had lost the conceptus. Though in the endometrium some lesions were observed like exudate in the glandular light, expansion of this light and edema periglandular, the principal change is the great inflammatory infiltration that includes: neutrophils, eosinophils, lymphocytes, natural killer cells, plasmatic cells and macrophages. In the miometrium and perimetrium there were mast cells. These cells might be responsible for the embryonic death because alter the local immunological state necessary for the gestation. Also it was a notable find the great quantity of cells in apoptosis in the luminal and glandular epithelium and in the corion of the endometrium. The death of the luminal epithelium might alter the normal implantation and that of the glandular cells the production of histiotropho. Both processes also might participate in the embryonic early death. the endometrium some lesions were observed like exudate in the glandular light, expansion of this light and edema periglandular, the principal change is the great inflammatory infiltration that includes: neutrophils, eosinophils, lymphocytes, natural killer cells, plasmatic cells and macrophages. In the miometrium and perimetrium there were mast cells. These cells might be responsible for the embryonic death because alter the local immunological state necessary for the gestation. Also it was a notable find the great quantity of cells in apoptosis in the luminal and glandular epithelium and in the corion of the endometrium. The death of the luminal epithelium might alter the normal implantation and that of the glandular cells the production of histiotropho. Both processes also might participate in the embryonic early death. tried for its coloration with HE, Giemsa, Toluidina’s Blue and for the histochemistry tecniques of PAS and TUNNEL. Some animals already lost its pregnancy in the day 6. In most cases the animals of more than 8 days of pregnancy had lost the conceptus. Though in the endometrium some lesions were observed like exudate in the glandular light, expansion of this light and edema periglandular, the principal change is the great inflammatory infiltration that includes: neutrophils, eosinophils, lymphocytes, natural killer cells, plasmatic cells and macrophages. In the miometrium and perimetrium there were mast cells. These cells might be responsible for the embryonic death because alter the local immunological state necessary for the gestation. Also it was a notable find the great quantity of cells in apoptosis in the luminal and glandular epithelium and in the corion of the endometrium. The death of the luminal epithelium might alter the normal implantation and that of the glandular cells the production of histiotropho. Both processes also might participate in the embryonic early death. the endometrium some lesions were observed like exudate in the glandular light, expansion of this light and edema periglandular, the principal change is the great inflammatory infiltration that includes: neutrophils, eosinophils, lymphocytes, natural killer cells, plasmatic cells and macrophages. In the miometrium and perimetrium there were mast cells. These cells might be responsible for the embryonic death because alter the local immunological state necessary for the gestation. Also it was a notable find the great quantity of cells in apoptosis in the luminal and glandular epithelium and in the corion of the endometrium. The death of the luminal epithelium might alter the normal implantation and that of the glandular cells the production of histiotropho. Both processes also might participate in the embryonic early death.