Influence of Inter and Intramolecular Hydrogen Bondd on the tautoomersim of beta-ketoamides: and NMR and theoretical study

SERGIO LAURELLA; AGUSTÍN SPALTRO; DANILA RUIZ; PATRICIA E. ALLEGRETTI

Congreso; 13th Latin Conference on Physical Organic Chemistry; 2015

beta- ketoamides appears to be affected by solvent polarity, subsituents (electronics and steric effects), concetration and temperature. We have determined enthaply and entropy for all eleven compounds. We have suggested that equilibrium shifts an thermodynamic parameters are strongly affected by intramoleular hydrogen bonds, which can be established only in ceto/ enol isomers