INVESTIGADORES
ABRAHAM Gustavo Abel
congresos y reuniones científicas
Título:
An in vitro set up for the assessment of electrospun nanofibrous vascular grafts
Autor/es:
D. SUAREZ BAGNASCO; L. CYMBERKNOP; F. MONTINI BALLARIN; G. BALAY; C. NEGREIRA; G.A. ABRAHAM; R.L. ARMENTANO
Lugar:
Paraná, Entre Ríos
Reunión:
Congreso; VI Congreso Latinoamericano de Ingeniería Biomédica (CLAIB 2014); 2014
Institución organizadora:
CLAIB
Resumen:
Introduction:
An experimental setup, using gold standard and high resolution ultrasound
techniques, was adapted to characterize electrospun vascular grafts in vitro. Materials
and Methods: Grafts were subjected to near physiologic pulsatile pressure conditions,
following the criteria stated in the international standard for cardiovascular
implants-tubular vascular prostheses. Results: Internal pressure and external diameter
variations of Poly(L-lactic acid) (PLLA) vascular grafts were obtained,
allowing the assessment of mechanical parameters. Dynamic compliance was
observed to decrease significantly in most cases, as transmural pressure
increases. Conclusion: Mechanical characterization of small diameter
electrospun PLLA vascular grafts was adequately achieved.