PHASE BEHAVIOR OF ASCORBYL PALMITATE IN PEG400 SOLUTION

LUCIANO BENEDINI ; PAULA V. MESSINA; PABLO C. SCHULZ; DANIEL ALLEMANDI; SANTIAGO D. PALMA

Congreso; 1º Reunión Internacional de Ciencias Farmaceuticas (RICiFA; 2010

Liquid crystals (LC) have a high degree of internal order and symmetry, combined with a large interfacial area and balanced hydrophobic and hydrophilic domains content. These properties make the LC excellent universal drug carriers, with numerous advantages over most other systems currently used20. That is the reason why phase behavior of Ascorbyl Palmitate (Asc16) in solution of polietileneglycol 400 (PEG 400) have been developed. The knowledge of phase behaviors is important to describe possible zones where mesophases are present. Stabilization of these phases may carry out to new drug carrier.