Electrostatic Analysis of the Aggregation of TrV Viral Particles.

MARCELO D. COSTABEL; MARÍA J. AMUNDARAIN; FERNANDO ZAMARREÑO; RUBÉN SÁNCHEZ-EUGENIA; JON AGUIRRE; DIEGO M.A. GUÉRIN

Baltimore

Congreso; Biophysical Society 55th Annual Meeting.; 2011

Biophysical Society

Triatoma virus (TrV) is a member of the insect virus family Dicistroviridae, a family similar to the vertebrate picornaviruses. TrV virions consist of a non-enveloped capsid that encloses the viral genome, a molecule of linear positive sense single-stranded RNA of about 9000 bases. The atomic structure of the capsid is an icosahedron (T=1, pseudo-equivalence p=3) of about 30 nm in diameter that encloses 60 repeats of three structural proteins VP1, VP2, and VP3 (MWs of about 39 kDa, 37 kDa, and 33 kDa; RCSB PDB code 3NAP).