INVESTIGADORES
JUSTEL Nadia Romina
congresos y reuniones científicas
Título:
Use of novelty as a way of modulates cSNC expression: implications of the adrenergic system.
Autor/es:
JUSTEL, N., PSYRDELLIS, M., PAUTASSI, R., & MUSTACA, A.
Reunión:
Congreso; XVII CONGRESO SOCIEDAD INTERNACIONAL DE PSICOLOGIA COMPARADA - 17th Biennial Meeting of the International Society; 2014
Resumen:
When
the subjects are exposed to a novel situation pre training or pre testing in a
specific learning situation, its retrieval is modulated (Izquierdo
& McGaugh, 1985, 1987, Justel, Pautassi & Mustaca, 2014). This
phenomenon involves a complex series of neurobiological and psychological
mechanisms (Thiel,Huston & Schwarting, 1998). On the other hand, animal´s behavior depends on their
previous experience with different reward values. One way to study this
phenomenon is with the incentive downshift paradigm through the consummatory
successive negative contrast. Thus, the aim of this work is to evaluate if the
presentation of an open field exposure disturbs the incentive downshift and the
role of the noradrenergic system in this phenomenon. For that purpose we submitted male rats to a
32% sucrose solution and then it was change it to a 4% one. Previously to the
first or second contact with the downshifted sucrose solution the animals
explored an open field. We found that the exposition to the open field
interfered with the aversive memory of the event. Through the propranolol´s
administration (an antagonist of the β-adrenergic system) or a vehicle
substance to the animals, given in trials 1 or 2 of the devaluation phase, it
was founded that this drug blocked the effect of open field. In a theoretical
level we want to understand the neurobiological processes involved in emotional
memory. The implications for the applied science are to provide research to
achieve better interventions for subjects who are vulnerable to loss situations
o deceptions.