Treatment planning assessment of a 9Be(d,n)-based neutron source for a real Glioblastoma Multiforme case

MARIA S. HERRERA; EUGENIA CAPOULAT; SARA J. GONZÁLEZ; DANIEL M. MINSKY; ANDRÉS J. KREINER

Congreso; 15th International Congress on Neutron Capture Therapy; 2012

Our previous studies based on a Snyder head phantom showed that 30mA deuteron beam of 1.45 MeV on a 8 micron-thick Be target could provide a suitable epithermal neutron source to treat brain tumors with BNCT. In this work, we evaluate the dose performance of such neutron source for the treatment of a real patient with diagnosed glioblastoma multiforme. The results are compared to those obtained with an optimized BSA neutron source based on the 7Li(p,n) reaction. Preliminary results show that a significant mean tumor dose of 42 Gy-Eq can be delivered with the proposed scheme while keeping the average whole brain dose lower than 4 Gy-Eq for an irradiation time of about 60 minutes.