“Aflatoxin B1 adsorption by yeast cell from commercial origin”

KELLER K., ; ALMEIDA T., ; CASTRO R., ; PEREYRA C., ; DALCERO A., ; CAVAGLIERI L., ; ROSA C.A.R.

Merida, Yucatán.

Congreso; VI Latin America Congress of Mycotoxicology. II International Symposium on fungal and algal toxins in industry; 2010

Among more than 300 mycotoxins described as yet, aflatoxin B1 (AFB1) and the group of fumonisins (FBs) are the toxins of major concern in tropical and subtropical regions. Aflatoxins are toxic secondary metabolites produced by species of Aspergillus genus, mainly A. flavus and A. parasiticus and its effects are carcinogenic, mutagenic, teratogenic and hepatoxic. Aflatoxin B1 is one of the most potent known hepatocarcinogens. Mycotoxin contamination of feed is a serious problem because they reduce feed consumption, decrease growth rate and reduce immunity. Besides the health aspects, which involves the presence of toxins or toxic metabolic products in food and / or by-products such as meat intended for human consumption, its presence in animal feed has also important economic connotations causing losses by increasing mortality and production (Rosa et al., 2001, 2006). One of the most effective methods to control risks of mycotoxins in animal husbandry is based on the use of specific materials that adsorb mycotoxins. These substances adsorb the toxins in the gastrointestinal tract to form insoluble complexes that are eliminated in the feces. Thus, the toxic effects are diminished by reducing the bioavailability of mycotoxins. In particular, the use yeast cell â-glucans and mannans- walls (PL), mainly composed of oligosaccharides. They are usually introduced as a food additive in the animal production industry since the 90s. To evaluate the efficacy of a commercial yeast cell wall to adsorb AFB1.