Exploration of heavy metal resistance in the yeast Wickerhamomyces anomalus: Implications for bioremediation

GAROLERA, B; PAJOT, HIPÓLITO F.; FERNANDEZ, P

Congreso; XIII Argentine Congress of Bioinformatics and Computational Biology (XIII CAB2C); 2023

The inadequate disposal of wastewater containing toxic heavy metals and industrial contaminants has become a critical issue today, posing serious risks to the health of humans, animals, and the environment. Numerous studies have investigated how heavy metals are absorbed, accumulated, and transformed using microorganisms (1). The yeast strain WickerhamomycesanomalusM10 has demonstrated notable resistance to several heavy metals, showing promising potential for bioremediation (2). Therefore, through computational methods (In Silico studies) to investigate metal resistance mechanisms, relevant genes related to this resistance were identified. Specialized databases like BacMetand InterProwere used (3), compiling genes from bacteria and fungi that enhance survival under environmental stress,