UTERINE INVOLUTION DURING EARLY POSTPARTUM IN SUCKLED BEEF COWS IN GRAZING CONDITIONS

VICTOR LEAVI DE ASIS; KAREN D. MORAN; LUISINA CHAPERO; MARÍA FLORENCIA FARCEY; JUAN PABLO PICCINI; EVELIN MARIEL ELIA; VALERIA ANALÍA SANDER; JULIÁN A. BARTOLOMÉ; MARÍA GUILLERMINA BILBAO

Mar del Plata

Congreso; Reunión Anual de Sociedades de Biociencias; 2023

la Sociedad Argentina de Investigación Clínica (SAIC), la Sociedad Argentina de Biología (SAB), la Asociación Argentina de Farmacología Experimental (AAFE) y la Asociación Argentina de Ciencia y Tecnología de Animales de Laboratorio (AACYTAL)

Cow-calf profitability depends on maintaining one-year calving intervals, underscoring the value of calving-conception reduction. This study aimed to assess endometrial status in the initial 60 days post-calving. Fifteen cows were enrolled in this trial. Glucose (mg/dL), Urea (g/L), Progesterone (ng/mL), vaginal discharge (VD, scale from 0 to 3), and polymorphonuclear cell count (%PMN) were evaluated at 30, 45, and 60 days postpartum (DPP). Relative expression of antioxidant defenses (CAT, SOD, GPx) and inflammation markers (TNFα, IL-6, IL-1β) using RPL19 as a housekeeping gene was evaluated in a subset (n=5). Marginal models were employed to analyze repeated measures, with time as a fixed effect and the individual cow as a random effect. The association was evaluated using the McNear test, and the Friedman test was used if normality was lacking. Antioxidant defenses correlation was assessed using the Pearson test. No variation was observed in Glucose (P=0.612) and Urea (P=0.235). A total of 73.34% (11/15) of cows resumed cyclicity. The proportion of cows with VD=0 was 73.33%, 80.00%, and 73.33% at 30, 45, and 60 DPP, respectively, without any association between these time points. No variation in %PMN was detected (P=0.983). SOD exhibited variation across DPP (P=0.010). Decreased expression was noted between 30 and 45 DPP (P=0.009), as well as between 30 and 60 DPP (P=0.041), with no difference between 45 and 60 DPP (P=0.950). No effect of DPP on the other two antioxidant defenses was observed (GPx: P=0.173; CAT: P=0.369). However, the expression of all three enzymes showed a strong correlation (SOD-CAT: r=0.564, P