Comparative genomics of the transition to life on land across mollusks

ARÍSTIDE, LEANDRO; SIMÓN GUERRERO, CAROLINA; TONZO, VANINA; FERNÁNDEZ, ROSA

Vigo

Congreso; VIII Congreso de la Sociedad Española de Biología Evolutiva; 2022

Sociedad Española de Biología Evolutiva

Theexpansion of the ecological niche of animals from purely aquatic environmentsinto land constitutes one of the most dramatic ecological and evolutionaryevents in Earth´s history. Noticeably, this transition occurred repeatedlyacross numerous animal lineages, providing the opportunity to study the genomicunderpinnings of such convergent adaptive processes. Here we performed acomparative genomic analysis of the Mollusca radiation, a highly diverse groupof invertebrates, to explore lineage-specific genomic changes associated withtransitions to life on land. To do so, we de novo assembled high-qualitytranscriptomic and genomic data from 107 species, encompassing all majormolluscan clades (i.e. orders) and several evolutionary independent transitionsout of marine environments. We reconstructed the evolutionary dynamics of genefamilies along the phylogeny of the phylum, and estimated gene gain and lossrates across these gene families. We identified several gene families withsignificantly elevated rates of change in size in lineages where transitions tolife on land have occurred. Here we present, explore and discuss the potentialfunctional and adaptive significance of these findings. Our results set theroad towards understanding the genomic underpinnings of molluskterrestrialization at a deeper level.@font-face{font-family:"Cambria Math";panose-1:2 4 5 3 5 4 6 3 2 4;mso-font-charset:0;mso-generic-font-family:roman;mso-font-pitch:variable;mso-font-signature:-536870145 1107305727 0 0 415 0;}@font-face{font-family:Calibri;panose-1:2 15 5 2 2 2 4 3 2 4;mso-font-charset:0;mso-generic-font-family:swiss;mso-font-pitch:variable;mso-font-signature:-536859905 -1073732485 9 0 511 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal{mso-style-unhide:no;mso-style-qformat:yes;mso-style-parent:"";margin-top:0cm;margin-right:0cm;margin-bottom:10.0pt;margin-left:0cm;line-height:115%;mso-pagination:widow-orphan;mso-hyphenate:none;font-size:11.0pt;font-family:"Calibri",sans-serif;mso-ascii-font-family:Calibri;mso-ascii-theme-font:minor-latin;mso-fareast-font-family:Calibri;mso-fareast-theme-font:minor-latin;mso-hansi-font-family:Calibri;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-bidi;}p.MsoBodyText, li.MsoBodyText, div.MsoBodyText{mso-style-unhide:no;mso-style-link:"Body Text Char";margin-top:0cm;margin-right:0cm;margin-bottom:7.0pt;margin-left:0cm;line-height:115%;mso-pagination:widow-orphan;mso-hyphenate:none;font-size:11.0pt;font-family:"Calibri",sans-serif;mso-ascii-font-family:Calibri;mso-ascii-theme-font:minor-latin;mso-fareast-font-family:Calibri;mso-fareast-theme-font:minor-latin;mso-hansi-font-family:Calibri;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-bidi;}span.BodyTextChar{mso-style-name:"Body Text Char";mso-style-unhide:no;mso-style-locked:yes;mso-style-link:"Body Text";mso-ansi-font-size:11.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri",sans-serif;mso-ascii-font-family:Calibri;mso-ascii-theme-font:minor-latin;mso-fareast-font-family:Calibri;mso-fareast-theme-font:minor-latin;mso-hansi-font-family:Calibri;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:EN-US;}.MsoChpDefault{mso-style-type:export-only;mso-default-props:yes;font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;mso-ansi-language:EN-GB;mso-fareast-language:EN-GB;}.MsoPapDefault{mso-style-type:export-only;mso-hyphenate:none;}div.WordSection1{page:WordSection1;}