CONICET | Buscador de Institutos y Recursos Humanos

Correlations between data derived from the Fourier spectrum and bone mass and bone mineral density. Puche RC, Rigalli A, Moreno H, Miguel JC. Vertebral trabecular bone. Bone. 41(6) S1,2007. Elsevier. The sheridam Press. Pennsylvania. USA This work correlates variables derived from the Fourier spectrum of vertebral trabecular bone with its bone mass and bone mineral density. Vertebral bodies had no compression fractures or wedging greater than 8 º. Midsagital sections of dry and defatted human vertebrae (T11 to L5, n=13), 1.65+0.2 mm thick were obtained with the aid of low speed metalographic saw. Sections were weighed in air and submerged into ethanol to measure the volume of bone tissue through the Archimede´s Principle. Section area were measured in mm2 and their volume calculated multiplying the latter by the thickness. Bone mass is the fraction of the section volume occupied by bone tissue. The weight of section ashes (obtained by incineration) allowed to determine the BMD expressed as grams/cm3 of trabecular bone or as grams/cm3 of vertebral tissue. Digital images of the section were obtained using transillumination. Simmetry of Fourier spectra was assessed through the autocorrelation function. Six eig envalues (ratio between the craneocaudal and anteroposterior diameters) were calculated at the low frequencies zone. The vertebrae had bone masses of 11.6 to 31.4% (v/v) and BMD of 0.1-0.3 g/cm3 of trabecular bone and 1.33 - 2.33 g/cm2 of vertebral tissue. The eigenvalues ranged between 0.4 (low bone mass) to 0.9 (high bone mass). The correlation between eigenvalues and bone mass was highly significant (r=0.795, P<0.001). Bone mass correlated positively with BMD of vertebral tissue (p = 0.05) and negatively with BMD pf trabecular bone (p = 0.07). The data supports the hypothesis that along the course of agaeing (reduction in bone mass), the mineral is redistributed within bone matrix, increasing the strength of the structure

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