Antifungal activity of raw extracts and purified compounds from Lorantaceae against plant pathogens

SOBERÓN, J. R.; SGARIGLIA, M. A.; SAMPIETRO, D. A .; VATTUONE, M. A.

Tafi del Valle

Congreso; XXVII Annual scientific meeting of the Tucuman biology association; 2010

Tucuman biology association

Phytopathogenic fungi cause diseases that disminish harvest yields around the world, causing economic lossess harful effects on health through mycotoxin contamination. Tripodanthus acutifolius (Ruiz and Pav) Tiegh and Ligaria cuneifolia (Ruiz and Pav) Tiegh contain phenols with known antibacterial activities, although there are no data concerning their antifungal effects. The antifungal activities of L. cuneifolia methanolic extract from the aerial parts (MeOHL), the methanolic extract (MeOHT) and tripodanthoside (main constituent) from T. acutifolius infusion were assayed against phytopathogenic fungi. Fusarium strains from Graminearum and Gibberella fujikuroi complexes and other genera strains were tested. These strains are very resistant to commercial antifungals. Inhibition of hyphal radial growth was evaluated using sterile disks loaded with 1 to 5 mg  of samples. Ketoconazole was used as a reference drug MeOHL and tripodanthoside showed antifungal activity against F. graminearum and F. thapsinum, although other strains (F. verticillioides, F. proliferatum, and Macrophomina phaseolina) were not inhibited. The results justify further studies of these extracts as sources of antifungal compounds.