Study of cardiac function in pulmonary hypertension by nuclear magnetic resonance

CARRIZO ALVARO; GUSTAVO ANDRÉS SOCOLSKY; ORELLANA S; JOO TURONI CLAUDIO

New Orleans (online)

Congreso; AARS 2022 Annual Meeting; 2022

American Roentgen Ray Society

Pulmonary hypertension (PHT) is a disease with a high morbimortality. Physiopathologically, PHT produces an increase in volumes and a decrease in the systolic function of the right ventricle (RV) that leads to right heart failure due to overload, which is difficult to assess, since, although the function of the left ventricle (LV) is very well studied by Doppler echocardiography, this method has limitations in the evaluation of the RV. Thus, Cardiac Magnetic Resonance (CMR) arises for the functional study of the RV, duet to its spatial and temporal resolution and its multiplanar capacity. Therefore, the objective of present study was to evaluate cardiac function (RV and LV) in patients with PHT using CMR.MATERIAL AND METHOD: 9 patients with severe PHT (age 52±5 years, 5 women) referred for evaluation by CMR (Philips Achieva 1.5 Tesla Resonator) were studied, performing Cines Balanced FFE sequences for the study of cardiac anatomy and volumes, and IR-ETFE late sequence 10 minutes after Gadolinium administration, to assess late enhancement (myocardial fibrosis / necrosis study). This group was compared with a control group of patients without PHT of similar age and distribution by sex (n = 9). Exclusion criteria: patients with ischemic heart disease or RV injury from another cause. RV and LV end-diastolic (VTD) and end-systolic (VTS) volumes, area of the right atrium (RA) and left (LA), trunk diameter, right and left pulmonary artery (PA) branch, abnormal movement of the septum were measured. interventricular (IVT) and presence of late enhancement. Ejection fraction (EF) of RV and LV was calculated. The VTD and VTS of both ventricles were indexed to the patient's body surface.The results were presented as a number n of determinations ± standard error. Student's t test or Pearson's correlation were performed. A difference less than 5% (p