Luteolin: cyto-genotoxic effects on normal cells

CARIDDI LN; MONTIRONI I; SABINI MC

Luteolin: Natural Occurrences, Therapeutic Applications and Health Effects. Series: Plant Science Research and Practices

Nova Science Publishers Inc

Lugar: Nueva York; Año: 2015; p. 101 - 107

Luteolin belongs to a group of naturally occurring compounds called flavonoids that are found widely in the plant kingdom. Different studies are focused on their beneficial properties of luteolin but little is known about the damage of this flavone in normal host cells. The studies conducted in order to evaluate the cyto-genotoxic effects of luteolin on normal animal and human cells showed diverse results that reveal that this flavone could have toxic effects depending on diverse factors as concentration, test carried out (in vitro or in vivo), time and mode of administration and type of cell. Because there are many biological