Magnetic Nanoparticles for Immune System Related Diseases Treatment

BOUDOU, F.G.; GIORGI, E.D.; DÍAZ, M.E.; ROCHA, G.F.; CONTI, F.S.; GENOVÉS, S.; DE DIEGO, G.A.; GUERRA, L.N.; DE MARZI, M.C.

Magnetic Nanoparticles for Biomedical Applications

Materials Research Forum LLC

Lugar: Millersville; Año: 2023; p. 253 - 277

Nanotechnology is a continuously rising field with different and varied purposes.Nanoparticles (NPs) are defined as particles between 1 and 100 nanometers in diameter,but within this classification larger particles can be incorporated up to 500 nm. MagneticNPs (MNPs) are generally composed with magnetic elements such as nickel, cobalt andiron, and have the ability to be manipulated through a magnetic field. Recently, these havebeen the subject of numerous studies because their attractive properties for several potentialapplications. Among them, we can include its use for diagnosis and medical treatment(theragnosis). Due to their properties, MNPs could be used with the aim of developingimmunomodulatory therapies and deal with infectious diseases, cancer, allergies,autoimmune diseases, etc. The use of MNPs provides a novel tool to manipulate theimmune response towards a profile according to the proposed objectives. That is why thischapter describes the interaction of MNPs with the immune system as well as its possibleapplications in immunomodulatory therapies.