INVESTIGADORES
RABINOVICH Gabriel Adrian
capítulos de libros
Título:
GALECTINS
Autor/es:
RICHARD D. CUMMINGS; FU-TONG LIU; GABRIEL RABINOVICH; SEAN R. STOWELL; GERARDO R. VASTA
Libro:
ESSENTIALS OF GLYCOBIOLOGY
Editorial:
Cold Spring Harbor Laboratory Press
Referencias:
Lugar: New York; Año: 2022; p. 400 - 420
Resumen:
Galectins are among the most widely expressed class of lectins in all organisms. They typically bind β-galactose-containing glycoconjugates and share primary structural homology in their carbohydrate-recognition domains (CRDs). Galectins have many biological functions, including roles in development, regulation of immune cell activities, and microbial recognition as part of the innate immune system. This chapter describes the diversity of the galectin family and presents an overview of what is known about their biosynthesis, secretion, and biological roles.