BALSA, LUCÍA M.; SANTA MARIA DE LA PARRA, LUCÍA; FERRETTI, VALERIA; LEÓN, IGNACIO E.

Deciphering the Effect of a Cu(II)‐hydrazone Complex on Intracellular Cell Signalling Pathways in a Human Osteosarcoma 2D and 3D Models

CHEMBIOCHEM; Año: 2024 vol. 25

SANTA MARIA DE LA PARRA, LUCÍA; BALSA, LUCÍA M.; LEÓN, IGNACIO E.

Metallocompounds as anticancer agents against osteosarcoma

DRUG DISCOVERY TODAY; Año: 2024 vol. 29

BALSA, LUCIA M.; VALERIA FERRETTI; MARCO SOTTILE; PATRIQUE NUNES; JOÃO COSTA PESSOA; ISABEL CORREIA; IGNACIO E. LEÓN

New copper(ii) and oxidovanadium(iv) complexes with a vitamin B6 Schiff base: mechanism of action and synergy studies on 2D and 3D human osteosarcoma cell models

Dalton Transactions; Año: 2023 vol. 53 p. 3039 - 3051

BALSA, LUCIA M.; RODRIGUEZ, MARÍA R.; FERRARESI-CUROTTO, VERÓNICA; PARAJÓN-COSTA, BEATRIZ S.; GONZALEZ-BARÓ, ANA C.; LEÓN, IGNACIO E.

Finding New Molecular Targets of Two Copper(II)-Hydrazone Complexes on Triple-Negative Breast Cancer Cells Using Mass-Spectrometry-Based Quantitative Proteomics

International Journal of Molecular Sciences; Lugar: Basel; Año: 2023 vol. 24

BALSA, LUCIA M.; BARAN, ENRIQUE. J.; LEÓN, IGNACIO E.

Copper Complexes as Antitumor Agents: In vitro and In vivo Evidence

CURRENT MEDICINAL CHEMISTRY.; Año: 2023 vol. 30 p. 510 - 557

KLJUN, JAKOB; REBERNIK, MIHAELA; BALSA, LUCÍA M.; KLADNIK, JERNEJA; RAPU?, URO?; TROBEC, TOMA?; SEP?I?, KRISTINA; FRANGE?, ROBERT; LEÓN, IGNACIO E.; TUREL, IZTOK

Exploring pta Alternatives in the Development of Ruthenium–Arene Anticancer Compounds

MOLECULES; Año: 2023 vol. 28

BALSA, LUCIA M.; SOLERNÓ, LUISINA M.; RODRIGUEZ, MARIA R.; PARAJÓN-COSTA, BEATRIZ S.; GONZALEZ-BARÓ, ANA C.; ALONSO, DANIEL F.; GARONA, JUAN; LEÓN, IGNACIO E.

Cu(II)-acylhydrazone complex, a potent and selective antitumor agent against human osteosarcoma: Mechanism of action studies over in vitro and in vivo models

CHEMICO-BIOLOGICAL INTERACTIONS; Año: 2023 vol. 384

BURGOS-LÓPEZ, YACELIS; BALSA, LUCIA M.; PIRO, OSCAR E.; LEÓN, IGNACIO E.; GARCÍA-TOJAL, JAVIER; ECHEVERRÍA, GUSTAVO A.; GONZÁLEZ-BARÓ, ANA C.; PARAJÓN-COSTA, BEATRIZ S.

Tridentate acylhydrazone copper(II) complexes with heterocyclic bases as coligands. Synthesis, spectroscopic studies, crystal structure and cytotoxicity assays

POLYHEDRON; Año: 2022 vol. 213

BALSA, LUCIA M.; FERRARESI-CUROTTO, VERÓNICA; LAVECCHIA, MARTIN J.; ECHEVERRÍA, GUSTAVO A.; PIRO, OSCAR E.; GARCÍA-TOJAL, JAVIER; PIS-DIEZ, REINALDO; GONZÁLEZ-BARÓ, ANA C.; LEÓN, IGNACIO E.

Anticancer activity of a new copper( ii ) complex with a hydrazone ligand. Structural and spectroscopic characterization, computational simulations and cell mechanistic studies on 2D and 3D breast cancer cell models

DALTON TRANSACTIONS; Año: 2021 vol. 50 p. 9812 - 9826

RODRÍGUEZ, MARÍA R.; BALSA, LUCÍA M.; PIRO, OSCAR E.; ETCHEVERRÍA, GUSTAVO A.; GARCÍA-TOJAL, JAVIER; PIS-DIEZ, REINALDO; LEÓN, IGNACIO E.; PARAJÓN-COSTA, BEATRIZ P.; GONZÁLEZ-BARÓ, ANA C.

Synthesis, crystal structure, spectroscopic characterization, DFT calculations and cytotoxicity assays of a new cu(II) complex with an acylhydrazone Ligand derived from thiophene

Inorganics; Lugar: Basel; Año: 2021 vol. 9 p. 1 - 15

BALSA, LUCIA M.; RODRIGUEZ, MARIA R.; PARAJÓN?COSTA, BEATRIZ S.; GONZÁLEZ?BARÓ, ANA C.; LAVECCHIA, MARTIN J.; LEÓN, IGNACIO E.

Anticancer Activity and Mechanism of Action Evaluation of an Acylhydrazone Cu(II) Complex toward Breast Cancer Cells, Spheroids, and Mammospheres

CHEMMEDCHEM; Año: 2021 vol. 17

LEVÍN, PEDRO; BALSA, LUCÍA M.; SILVA, CARLOS P.; HERZOG, AUSTIN E.; VEGA, ANDRÉS; PAVEZ, JORGE; LEÓN, IGNACIO E.; LEMUS, LUIS

Artificial Chemical Nuclease and Cytotoxic Activity of a Mononuclear Copper(I) Complex and a Related Binuclear Double‐Stranded Helicate

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY; Año: 2021 vol. 2021 p. 4103 - 4112

FABRA, DAVID; MATESANZ, ANA I.; HERRERO, JORGE M.; ALVAREZ, CRISTINA; BALSA, LUCIA M.; LEON, IGNACIO E.; QUIROGA, ADORACION G.

Two Different Thiosemicarbazone Tauto‐Conformers Coordinate to Palladium (II). Stability and Biological Studies of the Final Complexes

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY; Año: 2021 vol. 2021 p. 1041 - 1049

BALSA, LUCIA M.; RUIZ, MARIA C.; SANTA MARIA DE LA PARRA, LUCIA; BARAN, ENRIQUE J.; LEÓN, IGNACIO E.

Anticancer and antimetastatic activity of copper(II)-tropolone complex against human breast cancer cells, breast multicellular spheroids and mammospheres

JOURNAL OF INORGANIC BIOCHEMISTRY; Año: 2020 vol. 204

BALSA, LUCIA M; QUISPE, PATRICIA; BARAN, ENRIQUE J; LAVECCHIA, MARTIN J; LEÓN, IGNACIO E

In silico and in vitro analysis of FAK/MMP signaling axis inhibition by VO-clioquinol in 2D and 3D human osteosarcoma cancer cells

METALLOMICS; Año: 2020 vol. 12 p. 1931 - 1940

RODRÍGUEZ, MARÍA R.; BALSA, LUCÍA M.; DEL PLÁ, JULIÁN; GARCÍA-TOJAL, JAVIER; PIS-DIEZ, REINALDO; PARAJÓN-COSTA, BEATRIZ S.; LEÓN, IGNACIO E.; GONZÁLEZ-BARÓ, ANA C.

Synthesis, characterization, DFT calculations and anticancer activity of a new oxidovanadium(iv) complex with a ligand derived from O-vanillin and thiophene

NEW JOURNAL OF CHEMISTRY; Año: 2019 vol. 43 p. 11784 - 11794

RODRÍGUEZ, MARÍA R.; DEL PLÁ, JULIÁN; BALSA, LUCÍA M.; LEÓN, IGNACIO E.; PIRO, OSCAR E.; ECHEVERRÍA, GUSTAVO A.; GARCÍA-TOJAL, JAVIER; PIS-DIEZ, REINALDO; PARAJÓN-COSTA, BEATRIZ S.; GONZÁLEZ-BARÓ, ANA C.

Cu(ii) and Zn(ii) complexes with a poly-functional ligand derived from: O -vanillin and thiophene. Crystal structure, physicochemical properties, theoretical studies and cytotoxicity assays against human breast cancer cells

NEW JOURNAL OF CHEMISTRY; Año: 2019 vol. 43 p. 7120 - 7129

BURGOS-LOPEZ, Y.; DEL PLÁ, J.; BALSA, L.M.; LEÓN, I.E.; ECHEVERRÍA, G.A.; PIRO, O.E.; GARCÍA-TOJAL, J.; PIS-DIEZ, R.; GONZÁLEZ-BARÓ, A.C.; PARAJÓN-COSTA, B.S.

Synthesis, crystal structure and cytotoxicity assays of a copper(II) nitrate complex with a tridentate ONO acylhydrazone ligand. Spectroscopic and theoretical studies of the complex and its ligand

INORGANICA CHIMICA ACTA; Año: 2018 vol. 487 p. 31 - 40

MATESANZ, ANA I.; JIMENEZ-FARACO, EVA; RUIZ, MARÍA C.; BALSA, LUCIA M.; NAVARRO-RANNINGER, CARMEN; LEÓN, IGNACIO E.; QUIROGA, ADORACION G.

Mononuclear Pd(II) and Pt(II) complexes with an α-N-heterocyclic thiosemicarbazone: Cytotoxicity, solution behaviour and interaction: Versus proven models from biological media

Inorganic Chemistry Frontiers; Año: 2018 vol. 5 p. 73 - 83