ALIPERTI CAR, LUCIO; SÁNCHEZ, IGNACIO E.

Genomic AT Bias Coupled with Amino Acid Metabolism Modulates Codon Usage

JOURNAL OF MOLECULAR EVOLUTION; Año: 2025 vol. 93 p. 379 - 394

BORKOSKY, SILVIA S.; PERALTA-MARTÍNEZ, RAMÓN; ARMELLA-SIERRA, ALICIA; ESPERANTE, SEBASTIÁN A.; LIZÁRRAGA, LEONARDO; GARCÍA-PARDO, JAVIER; VENTURA, SALVADOR; SÁNCHEZ, IGNACIO E.; DE PRAT-GAY, GONZALO

Experimental kinetic mechanism of P53 condensation-amyloid aggregation

BIOPHYSICAL JOURNAL; Año: 2025 vol. 124 p. 1658 - 1673

COUSO, LUCIANA L.; RODRIGUEZ, PABLO E.; SANCHEZ, IGNACIO ENRIQUE

Bioartefactos vivos, alienados y resucitados

QUíMICA VIVA; Lugar: Buenos Aires; Año: 2025

PERALTA?MARTINEZ, RAMON; VISENTIN, ARACELI; SALGUEIRO, MARIANO; BORKOSKY, SILVIA SUSANA; ALEIXO, MARIANA ARAUJO AJALLA; PORTUGAL, RODRIGO VILLARES; SANCHEZ, IGNACIO ENRIQUE; PRAT?GAY, GONZALO

Protein– RNA condensation kinetics via filamentous nanoclusters

PROTEIN SCIENCE; Año: 2025 vol. 34

COUSO, LUCIANA L.; RODRÍGUEZ, PABLO E.; SANCHEZ, IGNACIO ENRIQUE

Sistemas vivos, semivivos y zombis

QUíMICA VIVA; Lugar: Buenos Aires; Año: 2024

HERNANDEZ-BERTHET AS; APTEKMANN AA; TEJERO J; SANCHEZ IE; NOGUERA ME; ROMAN EA

Associating protein sequence positions with the modulation of quantitative phenotypes

Archives of Biochemistry and Biophysics; Año: 2024 vol. 755

GARCIA-MONTOJO M; FATHI S; RASTEGAR C; SIMULA E; DOUCET-O'HARE T; CHENG YH; ABRAMS R; PASTERNACK N; MALIK N; BACHANI M; DISANZA B; MARIC D; LEE MH; WANG H; SANTAMARIA U; LI W; SAMPSON K; LORENZO R; SANCHEZ IE; MEZGHRANI A; LI Y; SECHI L; PINEDA S; HEIMAN M; KELLIS M; STEINER J; NATH A

TDP-43 proteinopathy in ALS is triggered by loss of ASRGL1 and associated with HML-2 expression

NATURE COMMUNICATIONS; Año: 2024 vol. 15

SANCHEZ IE; GALPERN EA; FERREIRO DU

Solvent constraints for biopolymer folding and evolution in extraterrestrial environments

Proceedings of the National Academy of Sciences of the United States of America; Año: 2024 vol. 121

MEDICI I; BARTROLI L; GUAIMAS F; MOLINA C; FULGENZI F; SANCHEZ IE; COMERCI D; MONGIARDINI E; SOLER-BISTUÉ, ALFONSO

The distinct cell physiology of Bradyrhizobium at the population and cellular level

BMC MICROBIOLOGY; Año: 2024 vol. 24

COUSO, LUCIANA L.; SOLER-BISTUÉ, ALFONSO; APTEKMANN, ARIEL A.; SÁNCHEZ, IGNACIO E.

Ecology theory disentangles microbial dichotomies

ENVIRONMENTAL MICROBIOLOGY; Año: 2023 vol. 25 p. 3052 - 3063

SOLER?BISTUÉ, ALFONSO; COUSO, LUCIANA L.; SÁNCHEZ, IGNACIO E.

The evolving copiotrophic/oligotrophic dichotomy: From Winogradsky to physiology and genomics

ENVIRONMENTAL MICROBIOLOGY; Año: 2023

ALIPERTI, LUCIO; APTEKMANN, ARIEL A.; FARFAÑUK, GONZALO; COUSO, LUCIANA L.; SOLER-BISTUÉ, ALFONSO; SÁNCHEZ, IGNACIO E.

r/K selection of GC content in prokaryotes

ENVIRONMENTAL MICROBIOLOGY; Año: 2023 vol. 25 p. 3255 - 3268

GONZÁLEZ-FOUTEL, NICOLÁS S.; GLAVINA, JULIANA; BORCHERDS, WADE M.; SAFRANCHIK, MATÍAS; BARRERA-VILARMAU, SUSANA; SAGAR, AMIN; ESTAÑA, ALEJANDRO; BAROZET, AMELIE; GARRONE, NICOLÁS A.; FERNANDEZ-BALLESTER, GREGORIO; BLANES-MIRA, CLARA; SÁNCHEZ, IGNACIO E.; DE PRAT-GAY, GONZALO; CORTÉS, JUAN; BERNADÓ, PAU; PAPPU, ROHIT V.; HOLEHOUSE, ALEX S.; DAUGHDRILL, GARY W.; CHEMES, LUCÍA B.

Conformational buffering underlies functional selection in intrinsically disordered protein regions

Nature Structural and Molecular Biology; Año: 2022 vol. 29 p. 781 - 790

GLAVINA, JULIANA; RODRÍGUEZ DE LA VEGA, RICARDO C.; RISSO, VALERIA A.; LEONETTI, CÉSAR O.; CHEMES, LUCÍA B.; SÁNCHEZ, IGNACIO E.

Host diversification is concurrent with linear motif evolution in a Mastadenovirus hub protein

JOURNAL OF MOLECULAR BIOLOGY; Año: 2022 vol. 434

SÁNCHEZ, IGNACIO E.; GALPERN, EZEQUIEL A.; GARIBALDI, MARTÍN M.; FERREIRO, DIEGO U.

Molecular Information Theory Meets Protein Folding

JOURNAL OF PHYSICAL CHEMISTRY B - (Print); Año: 2022

APTEKMANN, ARIEL A.; BULAVKA, DENYS; NADRA, ALEJANDRO D.; SÁNCHEZ, IGNACIO E.

Transcription factor specificity limits the number of DNA-binding motifs

PLOS ONE; Año: 2022 vol. 17

COBOS, EVA S.; SÁNCHEZ, IGNACIO E.; CHEMES, LUCÍA B.; MARTINEZ, JOSE C.; MURCIANO-CALLES, JAVIER

A thermodynamic analysis of the binding specificity between four human pdz domains and eight host, viral and designed ligands

Biomolecules; Año: 2021 vol. 11

BULAVKA D; APTEKMANN AA; MENDEZ NA; KRICK T; SANCHEZ IE

Thousands of protein linear motif classes may still be undiscovered

PLOS ONE; Lugar: San Francisco; Año: 2021

LORENZO, RAMIRO; DEFELIPE, LUCAS A.; ALIPERTI, LUCIO; NIEBLING, STEPHAN; CUSTÓDIO, TÂNIA F.; LÖW, CHRISTIAN; SCHWARZ, JENNIFER J.; REMANS, KIM; CRAIG, PATRICIO O.; OTERO, LISANDRO H.; KLINKE, SEBASTIÁN; GARCÍA-ALAI, MARÍA; SÁNCHEZ, IGNACIO E.; ALONSO, LEONARDO G.

Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif

JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2021 vol. 279

NADRA, ALEJANDRO D.; RODRÍGUEZ, PABLO E.; GRUNBERG, RAIK; OLALDE, LAURA G.; SÁNCHEZ, IGNACIO E.

Developing synthetic biology in Argentina: the Latin American TECNOx community as an alternative way for growth of the field

CRITICAL REVIEWS IN BIOTECHNOLOGY; Año: 2020 vol. 40 p. 357 - 364

LORENZO JR; LEONETTI CO; ALONSO LG; SÁNCHEZ IE

NGOME-Lite: Proteome-wide prediction of spontaneous protein deamidation highlights differences between taxa

METHODS; Lugar: Amsterdam; Año: 2020

ALVAREZ-PAGGI, DAMIÁN; LORENZO, JUAN RAMIRO; CAMPOREALE, GABRIELA; MONTERO, LUCIANO; SÁNCHEZ, IGNACIO E; DE PRAT GAY, GONZALO; ALONSO, LEONARDO G

Topology Dictates Evolution of Regulatory Cysteines in a Family of Viral Oncoproteins

MOLECULAR BIOLOGY AND EVOLUTION; Año: 2019 vol. 36 p. 1521 - 1532

GLAVINA J; ROMAN EA; ESPADA R; DE PRAT GAY G; CHEMES LB; SÁNCHEZ IE

Interplay between sequence, structure and linear motifs in the adenovirus E1A hub protein

VIROLOGY; Lugar: Amsterdam; Año: 2018

CAMPOREALE, GABRIELA; LORENZO, JUAN R.; THOMAS, MARIA G.; SALVATIERRA, EDGARDO; BORKOSKY, SILVIA S.; RISSO, MARIKENA G.; SÁNCHEZ, IGNACIO E.; DE PRAT GAY, GONZALO; ALONSO, LEONARDO G.

Degenerate cysteine patterns mediate two redox sensing mechanisms in the papillomavirus E7 oncoprotein

Redox Biology; Año: 2017 vol. 11 p. 38 - 50

BORKOSKY, SILVIA S.; CAMPOREALE, GABRIELA; CHEMES, LUCÍA B.; RISSO, MARIKENA; NOVAL, MARÍA GABRIELA; SÁNCHEZ, IGNACIO E.; ALONSO, LEONARDO G.; DE PRAT GAY, GONZALO

Hidden Structural Codes in Protein Intrinsic Disorder

BIOCHEMISTRY; Año: 2017 vol. 56 p. 5560 - 5569

ESPADA, ROCÍO; SÁNCHEZ, IGNACIO E.; FERREIRO, DIEGO U.

Detailing Protein Landscapes under Pressure

BIOPHYSICAL JOURNAL; Año: 2016 vol. 111 p. 2339 - 2341

SANCHEZ IE

Optimal threshold estimation for binary classifiers using game theory

F1000Research; Año: 2016

FERREIRO DU; SÁNCHEZ IE

El pinball proteico

QUíMICA VIVA; Lugar: Buenos Aires; Año: 2015 vol. 14

SÁNCHEZ IE

Disfunción, actividad y disactividad proteica: estudios de la proteína E7 del virus del papiloma mediante biología molecular reversa

QUíMICA VIVA; Lugar: Buenos Aires; Año: 2015 vol. 14

PRETEL, E; SÁNCHEZ IE; FASSOLARI, M; CHEMES LB; DE PRAT GAY G

Conformational heterogeneity determined by folding and oligomer assembly routes of the interferon response inhibitor NS1 protein, unique to human respiratory syncytial virus

BIOCHEMISTRY; Lugar: Washington; Año: 2015

CHEMES LB; DE PRAT GAY G; SÁNCHEZ IE

Convergent evolution and mimicry of protein linear motifs in host-pathogen interactions

CURRENT OPINION IN STRUCTURAL BIOLOGY; Lugar: Londres; Año: 2015

BUSH A; GIMÉNEZ M; GRANDE A; MOROSI LG; PARASCO V; PARREÑO MA; RUGIERO M; SABIO G; COLMAN-LERNER A; NADRA AD; SÁNCHEZ IE

Synthetic Crossfeeding Cocultures in Yeast: Computational Model of Autoregulation and Design of a Tryptophan Export Device

Journal of Synthetic Biology; Año: 2015

VAZQUEZ DS; SÁNCHEZ IE; GARROTE A; SICA MP; SANTOS J

The E. coli Thioredoxin Folding Mechanism: The Key Role of the C-terminal Helix

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS; Lugar: Amsterdam; Año: 2015

LORENZO, JR; ALONSO, LG; SÁNCHEZ IE

Prediction of spontaneous protein deamidation from sequence-derived secondary structure and intrinsic disorder

PLOS ONE; Lugar: San Francisco; Año: 2015

KRICK T; VERSTRAETE N; ALONSO, LG; SHUB DA; FERREIRO DU; SHUB M; SÁNCHEZ IE

Amino acid metabolism conflicts with protein diversity

MOLECULAR BIOLOGY AND EVOLUTION; Lugar: Oxford; Año: 2014 vol. 31 p. 2905 - 2912

DINKEL H; VAN ROEY K; MICHAEL S; DAVEY NE; WEATHERITT RJ; BORN D; SPECK T; KRÜGER D; GREBNEV G; KUBAN M; STRUMILLO M; UYAR B; BUDD A; ALTENBERG B; SEILER M; CHEMES LB; GLAVINA J; SÁNCHEZ IE; DIELLA F; GIBSON TJ

The eukaryotic linear motif resource ELM: 10 years and counting.

NUCLEIC ACIDS RESEARCH; Lugar: Oxford; Año: 2014 vol. 42 p. 259 - 266

CHEMES LB; CAMPOREALE G; SÁNCHEZ IE; DE PRAT GAY G; ALONSO, LG

Cysteine-rich positions outside the structural zinc motif of human papillomavirus e7 provide conformational modulation and suggest functional redox roles.

BIOCHEMISTRY; Lugar: Washington; Año: 2014 vol. 53 p. 1680 - 1696

FASSOLARI, M; CHEMES LB; GALLO M; SMAL C; SÁNCHEZ IE; DE PRAT GAY G

Minute-timescale prolyl isomerization governs antibody recognition of an intrinsically disordered immunodominant epitope.

JOURNAL OF BIOLOGICAL CHEMISTRY (ONLINE); Año: 2013

PARRA RG; ESPADA R; SÁNCHEZ IE; SIPPL MJ; FERREIRO DU

Detecting Repetitions and Periodicities in Proteins by Tiling the Structural Space

JOURNAL OF PHYSICAL CHEMISTRY B; Año: 2013

CHEMES LB; NOVAL MG; SÁNCHEZ IE; DE PRAT GAY G

Folding of a cyclin box: linking multitarget binding to marginal stability, oligomerization and aggregation of the retinoblastoma tumor suppressor AB pocket domain

JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda, Maryland; Año: 2013 vol. 288 p. 18923 - 18938

CHEMES LB; GLAVINA J; FAIVOVICH J; DE PRAT GAY G; SÁNCHEZ IE

Evolution of linear motifs within the papillomavirus E7 oncoprotein

JOURNAL OF MOLECULAR BIOLOGY; Lugar: Amsterdam; Año: 2012 vol. 422 p. 336 - 346

CHEMES LB; GLAVINA J; ALONSO, LG; MARINO-BUSLJE C; DE PRAT GAY G; SÁNCHEZ IE

Sequence evolution of the intrinsically disordered and globular domains of a model viral oncoprotein.

PLOS ONE; Lugar: San Francisco; Año: 2012 p. 1 - 10

CHEMES LB; SÁNCHEZ IE; DE PRAT GAY G

Kinetic recognition of the retinoblastoma tumor suppressor by a specific protein target.

JOURNAL OF MOLECULAR BIOLOGY; Lugar: Amsterdam; Año: 2011 vol. 412 p. 267 - 284

ESPERANTE SA; CHEMES LB; SÁNCHEZ IE; DE PRAT GAY G

The respiratory syncytial virus transcription antiterminator M(2-1) is a highly stable, zinc binding tetramer with strong pH-dependent dissociation and a monomeric unfolding intermediate

BIOCHEMISTRY; Lugar: Washington; Año: 2011 vol. 50 p. 8529 - 8539

SÁNCHEZ IE; FERREIRO DU; DE PRAT GAY G

Mutational analysis of kinetic partitioning in protein folding and protein-DNA binding

PROTEIN ENGINEERING DESIGN & SELECTION; Año: 2011 vol. 24 p. 179 - 184

DEVRIES I; FERREIRO DU; SÁNCHEZ IE; KOMIVES EA

Folding kinetics of the cooperatively folded subdomain of the IκBα ankyrin repeat domain

JOURNAL OF MOLECULAR BIOLOGY; Año: 2011 vol. 408 p. 163 - 176

SÁNCHEZ IE; FERREIRO DU; DELLAROLE M; DE PRAT GAY G

Experimental snapshots of a protein-DNA binding landscape.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2010 vol. 107 p. 7751 - 7756

CHEMES LB; SÁNCHEZ IE; SMAL C; DE PRAT GAY G

Targeting mechanism of the retinoblastoma tumor suppressor by a prototypical viral oncoprotein. Structural modularity, intrinsic disorder and phosphorylation of human papillomavirus E7.

FEBS JOURNAL; Año: 2010 vol. 277 p. 973 - 988

DELLAROLE M; SÁNCHEZ IE; DE PRAT GAY G

Thermodynamics of cooperative DNA recognition at a replication origin and transcription regulatory site

BIOCHEMISTRY; Año: 2010 vol. 49 p. 10277 - 10286

ENCINAR JA; FERNÁNDEZ-BALLESTER G; SÁNCHEZ IE; HURTADO-GÓMEZ E; STRICHER F; BELTRAO P; SERRANO L

ADAN: a database for prediction of protein-protein interaction of modular domains mediated by linear motifs.

BIOINFORMATICS (OXFORD, ENGLAND); Año: 2009 vol. 25 p. 2418 - 2424

ELISEO T; SÁNCHEZ IE; NADRA AD; DELLAROLE M; PACI M; DE PRAT GAY G; CICERO DO

Indirect DNA readout on the protein side: coupling between histidine protonation, global structural cooperativity, dynamics, and DNA binding of the human papillomavirus type 16 E2C domain.

JOURNAL OF MOLECULAR BIOLOGY; Año: 2009 vol. 388 p. 327 - 344

WETZLER DE; GALLO M; MELIS R; ELISEO T; NADRA AD; FERREIRO DU; PACI M; SÁNCHEZ IE; CICERO DO; DE PRAT-GAY G

A strained DNA binding helix is conserved for site recognition, folding nucleation, and conformational modulation.

BIOPOLYMERS; Año: 2009 vol. 91 p. 432 - 443

FERREIRO DU; SÁNCHEZ IE; DE PRAT GAY G

Transition state for protein-DNA recognition

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2008 vol. 105 p. 10803 - 10808

SÁNCHEZ IE; DELLAROLE M; GASTON K; DE PRAT GAY G

Comprehensive comparison of the interaction of the E2 master regulator with its cognate target DNA sites in 73 human papillomavirus types by sequence statistics

NUCLEIC ACIDS RESEARCH; Año: 2008 vol. 36 p. 756 - 769

SÁNCHEZ IE; BELTRAO P; STRICHER F; SCHYMKOWITZ J; FERKINGHOFF-BORG J; ROUSSEAU F; SERRANO L

Genome-wide prediction of SH2 domain targets using structural information and the FoldX algorithm

PLoS Computational Biology; Año: 2008 vol. 4 p. 52 - 61

SÁNCHEZ IE

Protein folding transition states probed by loop extension

PROTEIN SCIENCE; Año: 2008 vol. 17 p. 183 - 186

DELLAROLE M; SÁNCHEZ IE; FREIRE E; DE PRAT GAY G

Increased stability and DNA site discrimination of "single chain" variants of the dimeric beta-barrel DNA binding domain of the human papillomavirus E2 transcriptional regulator.

BIOCHEMISTRY; Año: 2007 vol. 46 p. 12441 - 12450

SÁNCHEZ IE; TEJERO J; GÓMEZ-MORENO C; MEDINA M; SERRANO L

Point mutations in protein globular domains: contributions from function, stability and misfolding

JOURNAL OF MOLECULAR BIOLOGY; Año: 2006 vol. 363 p. 422 - 432

BOLLEN YJ; SÁNCHEZ IE; VAN MIERLO CP

Formation of on- and off-pathway intermediates in the folding kinetics of Azotobacter vinelandii apoflavodoxin

BIOCHEMISTRY; Año: 2004 vol. 43 p. 10475 - 10489

SÁNCHEZ IE; KIEFHABER T

Fast folding of the two-domain semliki forest virus capsid protein explains co-translational proteolytic activity

JOURNAL OF MOLECULAR BIOLOGY; Año: 2004 vol. 338 p. 159 - 167

SÁNCHEZ IE; KIEFHABER T

Origin of unusual phi-values in protein folding: evidence against specific nucleation sites

JOURNAL OF MOLECULAR BIOLOGY; Año: 2003 vol. 334 p. 1077 - 1085

SÁNCHEZ IE; KIEFHABER T

Evidence for sequential barriers and obligatory intermediates in apparent two-state protein folding

JOURNAL OF MOLECULAR BIOLOGY; Año: 2003 vol. 325 p. 367 - 376

SÁNCHEZ IE; KIEFHABER T

Non-linear rate-equilibrium free energy relationships and Hammond behavior in protein folding

BIOPHYSICAL CHEMISTRY; Año: 2003 vol. 100 p. 397 - 407

SÁNCHEZ IE; KIEFHABER T

Hammond behavior versus ground state effects in protein folding: evidence for narrow free energy barriers and residual structure in unfolded states

JOURNAL OF MOLECULAR BIOLOGY; Año: 2003 vol. 327 p. 867 - 884