INVESTIGADORES
BIRNBAUMER Lutz
artículos
CHOI, JUNG-MI; ACHARYA, RAKSHYA; BIRNBAUMER, LUTZ; SUH-KIM, HAEYOUNG
CB1R activates the epilepsy-associated protein Go to regulate neurotransmitter release and synaptic plasticity in the cerebellum
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2024 vol. 121
SUN, ZHI CHUAN; HAN, WEN JUAN; DOU, ZHI WEI; LU, NA; WANG, XU; WANG, FU DONG; MA, SUI BIN; TIAN, ZHI CHENG; XIAN, HANG; LIU, WAN NENG; LIU, YING YING; WU, WEN BIN; CHU, WEN GUANG; GUO, HUAN; WANG, FEI; DING, HUI; LIU, YUAN YING; TAO, HUI REN; FREICHEL, MARC; BIRNBAUMER, LUTZ; LI, ZHEN ZHEN; XIE, ROU GANG; WU, SHENG XI; LUO, CENG
TRPC3/6 Channels Mediate Mechanical Pain Hypersensitivity via Enhancement of Nociceptor Excitability and of Spinal Synaptic Transmission
Advanced Science; Año: 2024 vol. 11
BRÖKER-LAI, JENNY; REGO TEROL, JOSÉ; RICHTER, CHRISTIN; MATHAR, ILKA; WIRTH, ANGELA; KOPF, STEFAN; MORENO-PÉREZ, ANA; BÜTTNER, MICHAEL; TAN, LINETTE LIQI; MAKKE, MAZEN; POSCHET, GERNOT; HERMANN, JULIA; TSVILOVSKYY, VOLODYMYR; HABERKORN, UWE; WARTENBERG, PHILIPP; SUSPERREGUY, SEBASTIAN; BERLIN, MICHAEL; OTTENHEIJM, ROGER; PHILIPPAERT, KOENRAAD; WU, MOYA; WIEDEMANN, TOBIAS; HERZIG, STEPHAN; BELKACEMI, ANOUAR; LEVINSON, REBECCA T; AGARWAL, NITIN; CAMACHO LONDOÑO, JUAN E; KLEBL, BERT; DINKEL, KLAUS; ZUFALL, FRANK; NUSSBAUMER, PETER; BOEHM, ULRICH; HELL, RÜDIGER; NAWROTH, PETER; BIRNBAUMER, LUTZ; LEINDERS-ZUFALL, TRESE; KUNER, ROHINI; ZORN, MARKUS; BRUNS, DIETER; SCHWARZ, YVONNE; FREICHEL, MARC
TRPC5 controls the adrenaline-mediated counter regulation of hypoglycemia
The EMBO Journal; Año: 2024
CAO, QIUHUA; ZHAO, MINGRUI; SU, YALI; LIU, SILIANG; LIN, YANTING; BIRNBAUMER, LUTZ; YANG, YONG; DAI, BEIYING; GAO, XINGHUA
Chronic Stress Dampens Lactobacillus Johnsonii –Mediated Tumor Suppression to Enhance Colorectal Cancer Progression
CANCER RESEARCH; Año: 2024 vol. 84 p. 771 - 784
LUO, HAICHANG; ANDERSON, ALLISON; MASUHO, IKUO; MARRON FERNANDEZ DE VELASCO, EZEQUIEL; BIRNBAUMER, LUTZ; MARTEMYANOV, KIRILL A.; WICKMAN, KEVIN
Receptor-dependent influence of R7 RGS proteins on neuronal GIRK channel signaling dynamics
PROGRESS IN NEUROBIOLOGY; Año: 2024 vol. 243
CONTRERAS, ELY; BHOI, JACOB D; SONODA, TAKUMA; BIRNBAUMER, LUTZ; SCHMIDT, TIFFANY M
Melanopsin activates divergent phototransduction pathways in intrinsically photosensitive retinal ganglion cell subtypes
eLife; Año: 2023 vol. 12
PARK, DO-YANG; HEO, WOON; KANG, MIRAN; AHN, TAEYOUNG; KIM, DOHYEON; CHOI, AYEON; BIRNBAUMER, LUTZ; CHO, HYUNG-JU; KIM, JOO YOUNG
Role of TRPC3 in Right Ventricular Dilatation under Chronic Intermittent Hypoxia in 129/SvEv Mice
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; Año: 2023 vol. 24
RACHED, GAËLLE; SALIBA, YOUAKIM; MADDAH, DINA; HAJAL, JOELLE; SMAYRA, VIVIANE; BAKHOS, JULES JOEL; GROSCHNER, KLAUS; BIRNBAUMER, LUTZ; FARES, NASSIM
TRPC3 Regulates Islet Beta‐Cell Insulin Secretion
Advanced Science; Año: 2023 vol. 10
HERTZ, LAURA; FLORMANN, DANIEL; BIRNBAUMER, LUTZ; WAGNER, CHRISTIAN; LASCHKE, MATTHIAS W.; KAESTNER, LARS
Evidence of in vivo exogen protein uptake by red blood cells: a putative therapeutic concept
Blood Advances; Año: 2023 vol. 7 p. 1033 - 1039
TAKURO NUMAGA-TOMITA; TSUKASA SHIMAUCHI; YURI KATO ; KAZUHIRO NISHIYAMA; AKIYUKI NISHIMURA; KOSUKE SAKATA ; HIROYUKI INADA; SATOMI KITA; TAKAHIRO IWAMOTO ; JUNICHI NABEKURA; LUTZ BIRNBAUMER ; YASUO MORI; MOTOHIRO NISHIDA
Inhibition of transient receptor potential cation channel 6 promotes capillary arterialization during post-ischaemic blood flow recovery
BRITISH JOURNAL OF PHARMACOLOGY; Lugar: Londres; Año: 2023
PARMAR, JASNEET; VON JONQUIERES, GEORG; GORLAMANDALA, NAGARAJESH; CHUNG, BRANDON; CRAIG, AMANDA J.; PINYON, JEREMY L.; BIRNBAUMER, LUTZ; KLUGMANN, MATTHIAS; MOORHOUSE, ANDREW J.; POWER, JOHN M.; HOUSLEY, GARY D.
TRPC Channels Activated by G Protein-Coupled Receptors Drive Ca2+ Dysregulation Leading to Secondary Brain Injury in the Mouse Model
Translational Stroke Research; Año: 2023 vol. 15 p. 844 - 858
SCHRÖPER, TOBIAS; MEHRKENS, DENNIS; LEISS, VERONIKA; TELLKAMP, FREDERIK; ENGELHARDT, STEFAN; HERZIG, STEFAN; BIRNBAUMER, LUTZ; NÜRNBERG, BERND; MATTHES, JAN
Protective effects of Gαi3 deficiency in a murine heart-failure model of β1-adrenoceptor overexpression
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY; Lugar: Berlin; Año: 2023 vol. 397 p. 2401 - 2420
PARMAR, JASNEET; VON JONQUIERES, GEORG; GORLAMANDALA, NAGARAJESH; CHUNG, BRANDON; CRAIG, AMANDA J.; PINYON, JEREMY L.; BIRNBAUMER, LUTZ; KLUGMANN, MATTHIAS; MOORHOUSE, ANDREW J.; POWER, JOHN M.; HOUSLEY, GARY D.
TRPC Channels Activated by G Protein-Coupled Receptors Drive Ca2+ Dysregulation Leading to Secondary Brain Injury in the Mouse Model
Translational Stroke Research; Año: 2023 vol. 15 p. 844 - 858
MALKMUS, KATHRIN; BROSIEN, MONIKA; KNOEPP, FENJA; SCHAFFELHOFER, LISA; GRIMMINGER, FRIEDRICH; RUMMEL, CHRISTOPH; GUDERMANN, THOMAS; DIETRICH, ALEXANDER; BIRNBAUMER, LUTZ; WEISSMANN, NORBERT; KRAUT, SIMONE
Deletion of classical transient receptor potential 1, 3 and 6 alters pulmonary vasoconstriction in chronic hypoxia-induced pulmonary hypertension in mice
Frontiers in Physiology; Año: 2022 vol. 13
TIAN, JIN-BIN; YANG, JANE; JOSLIN, WILLIAM C.; FLOCKERZI, VEIT; PRESCOTT, STEVEN A.; BIRNBAUMER, LUTZ; ZHU, MICHAEL X.
TRPC4 and GIRK channels underlie neuronal coding of firing patterns that reflect Gq/11-Gi/o coincidence signals of variable strengths
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2022 vol. 119
CAVAL-HOLME, FRANKLIN S.; ARANDA, MARCOS L.; CHEN, ANDY Q.; TIRIAC, ALEXANDRE; ZHANG, YIZHEN; SMITH, BENJAMIN; BIRNBAUMER, LUTZ; SCHMIDT, TIFFANY M.; FELLER, MARLA B.
The Retinal Basis of Light Aversion in Neonatal Mice
JOURNAL OF NEUROSCIENCE; Año: 2022 vol. 42 p. 4101 - 4115
WU, HONGXI; LI, YAN; SHI, GUANGJIANG; DU, SHIJIA; WANG, XIAOBIN; YE, WANLI; ZHANG, ZIXUAN; CHU, YA; MA, SHUQIAN; WANG, DAJIA; LI, YUAN; CHEN, ZHEN; BIRNBAUMER, LUTZ; WANG, ZHUO; YANG, YONG
Hepatic interferon regulatory factor 8 expression suppresses hepatocellular carcinoma progression and enhances the response to anti–programmed cell death protein-1 therapy
HEPATOLOGY (BALTIMORE, MD.); Año: 2022 vol. 76 p. 1602 - 1616
ZHANG, YING; WANG, CONG; LI, WEISHUO; TIAN, WEI; TANG, CHUNMING; XUE, LINGJING; LIN, ZIMING; LIU, GUILAI; LIU, DONGFEI; ZHOU, YING; WANG, QIANQIAN; WANG, XU; BIRNBAUMER, LUTZ; YANG, YONG; LI, XIANJING; JU, CAOYUN; ZHANG, CAN
Neutrophil Cyto-Pharmaceuticals Suppressing Tumor Metastasis via Inhibiting Hypoxia-Inducible Factor-1α in Circulating Breast Cancer Cells
Advanced Healthcare Materials; Año: 2022 vol. 11
DUAN, JINGJING; WANG, ZHUO; DUAN, RAN; YANG, CHENXINHUI; ZHAO, RUOLIN; FENG, QI; QIN, YUANYUAN; JIANG, JINGWEI; GU, SHOUYONG; LV, KAIYAN; ZHANG, LIBO; HE, BIXIA; BIRNBAUMER, LUTZ; YANG, SONG; CHEN, ZHEN; YANG, YONG
Therapeutic targeting of hepatic ACSL4 ameliorates NASH in mice
HEPATOLOGY (BALTIMORE, MD.); Año: 2022 vol. 75 p. 140 - 153
NUMAGA TOMITA, TAKURO; SHIMAUCHI, TSUKASA; KATO, YURI; NISHIYAMA, KAZUHIRO; NISHIMURA, AKIYUKI; SAKATA, KOSUKE; INADA, HIROYUKI; KITA, SATOMI; IWAMOTO, TAKAHIRO; NABEKURA, JUNICHI; BIRNBAUMER, LUTZ; MORI, YASUO; NISHIDA, MOTOHIRO
Inhibition of transient receptor potential cation channel 6 promotes capillary arterialization during post‐ischaemic blood flow recovery
BRITISH JOURNAL OF PHARMACOLOGY; Año: 2022 vol. 180 p. 94 - 110
NUMAGA TOMITA, TAKURO; SHIMAUCHI, TSUKASA; KATO, YURI; NISHIYAMA, KAZUHIRO; NISHIMURA, AKIYUKI; SAKATA, KOSUKE; INADA, HIROYUKI; KITA, SATOMI; IWAMOTO, TAKAHIRO; NABEKURA, JUNICHI; BIRNBAUMER, LUTZ; MORI, YASUO; NISHIDA, MOTOHIRO
Inhibition of transient receptor potential cation channel 6 promotes capillary arterialization during post‐ischaemic blood flow recovery
BRITISH JOURNAL OF PHARMACOLOGY; Año: 2022 vol. 180 p. 94 - 110
NUMAGA TOMITA, TAKURO; SHIMAUCHI, TSUKASA; KATO, YURI; NISHIYAMA, KAZUHIRO; NISHIMURA, AKIYUKI; SAKATA, KOSUKE; INADA, HIROYUKI; KITA, SATOMI; IWAMOTO, TAKAHIRO; NABEKURA, JUNICHI; BIRNBAUMER, LUTZ; MORI, YASUO; NISHIDA, MOTOHIRO
Inhibition of transient receptor potential cation channel 6 promotes capillary arterialization during post‐ischaemic blood flow recovery
BRITISH JOURNAL OF PHARMACOLOGY; Año: 2022 vol. 180 p. 94 - 110
NUMAGA TOMITA, TAKURO; SHIMAUCHI, TSUKASA; KATO, YURI; NISHIYAMA, KAZUHIRO; NISHIMURA, AKIYUKI; SAKATA, KOSUKE; INADA, HIROYUKI; KITA, SATOMI; IWAMOTO, TAKAHIRO; NABEKURA, JUNICHI; BIRNBAUMER, LUTZ; MORI, YASUO; NISHIDA, MOTOHIRO
Inhibition of transient receptor potential cation channel 6 promotes capillary arterialization during post‐ischaemic blood flow recovery
BRITISH JOURNAL OF PHARMACOLOGY; Año: 2022 vol. 180 p. 94 - 110
WANG, YUE; QUAN, FEI; CAO, QIUHUA; LIN, YANTING; YUE, CHONGXIU; BI, RAN; CUI, XINMENG; YANG, HONGBAO; YANG, YONG; BIRNBAUMER, LUTZ; LI, XIANJING; GAO, XINGHUA
Quercetin alleviates acute kidney injury by inhibiting ferroptosis
Journal of Advanced Research; Año: 2021 vol. 28 p. 231 - 243
HU, WEIWEI; ZHENG, SHUFANG; GUO, HAIXIN; DAI, BEIYING; NI, JIAPING; SHI, YAOHONG; BIAN, HANRUI; LI, LANXIN; SHEN, YUMENG; WU, MO; TIAN, ZHOUTONG; LIU, GUILAI; HOSSAIN, MD AMIR; YANG, HONGBAO; WANG, DUOWEI; ZHANG, QIN; YU, JUN; BIRNBAUMER, LUTZ; FENG, JIFENG; YU, DECAI; YANG, YONG
PLAGL2-EGFR-HIF-1/2α Signaling Loop Promotes HCC Progression and Erlotinib Insensitivity
HEPATOLOGY (BALTIMORE, MD.); Año: 2021 vol. 73 p. 674 - 691
HE, DONGXU; MAO, AIQIN; LI, YOURAN; TAM, SIUCHEUNG; ZHENG, YONGTANG; YAO, XIAOQIANG; BIRNBAUMER, LUTZ; AMBUDKAR, INDU S.; MA, XIN
TRPC1 participates in the HSV-1 infection process by facilitating viral entry
Science Advances; Año: 2021 vol. 6
HOSSAIN, MD AMIR; LIU, GUILAI; DAI, BEIYING; SI, YAXUAN; YANG, QITAO; WAZIR, JUNAID; BIRNBAUMER, LUTZ; YANG, YONG
Reinvigorating exhausted CD8+ cytotoxic T lymphocytes in the tumor microenvironment and current strategies in cancer immunotherapy
MEDICINAL RESEARCH REVIEWS; Año: 2021 vol. 41 p. 156 - 201
ZHANG, YE; YANG, XUE; YAN, WENCHAO; LI, RUI; YE, QIAN; YOU, LINJUN; XIE, WENHAO; MO, KUN; FU, RUIFENG; WANG, YANXIANG; CHEN, YUFEI; HOU, HUI; YANG, YONG; BIRNBAUMER, LUTZ; DI, QIN; LI, XIANJING
Thymopentin improves the survival of septic mice by promoting the production of 15-deoxy-prostaglandin J2 and activating the PPARγ signaling pathway
FASEB JOURNAL; Año: 2020 vol. 34 p. 11772 - 11785
LEISS, VERONIKA; SCHÖNSIEGEL, ANNIKA; GNAD, THORSTEN; KERNER, JOHANNES; KAUR, JYOTSNA; SARTORIUS, TINA; MACHANN, JÜRGEN; SCHICK, FRITZ; BIRNBAUMER, LUTZ; HÄRING, HANS-ULRICH; PFEIFER, ALEXANDER; NÜRNBERG, BERND
Lack of Gαi2 proteins in adipocytes attenuates diet-induced obesity
Molecular Metabolism; Año: 2020 vol. 40
SMITH, ANDREW H.; PUTTA, PRIYA; DRISCOLL, ERIN C.; CHAUDHURI, PINAKI; BIRNBAUMER, LUTZ; ROSENBAUM, MICHAEL A.; GRAHAM, LINDA M.
Canonical transient receptor potential 6 channel deficiency promotes smooth muscle cells dedifferentiation and increased proliferation after arterial injury
JVS: Vascular Science; Año: 2020 vol. 1 p. 136 - 150
ANDERSON, ALLISON; MASUHO, IKUO; DE VELASCO, EZEQUIEL MARRON FERNANDEZ; NAKANO, ATSUSHI; BIRNBAUMER, LUTZ; BIRNBAUMER, LUTZ; MARTEMYANOV, KIRILL A.; WICKMAN, KEVIN
GPCR-dependent biasing of GIRK channel signaling dynamics by RGS6 in mouse sinoatrial nodal cells
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2020 vol. 117 p. 14522 - 14531
FORMOSO, KARINA; SUSPERREGUY, SEBASTIAN; FREICHEL, MARC; BIRNBAUMER, LUTZ
RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways
Scientific Reports; Año: 2020 vol. 10
TSVILOVSKYY, VOLODYMYR; SOLIS-LOPEZ, ALEJANDRA; ALMERING, JULIA; RICHTER, CHRISTIN; BIRNBAUMER, LUTZ; DIETRICH, ALEXANDER; FREICHEL, MARC
Analysis of Mrgprb2 Receptor-Evoked Ca2+ Signaling in Bone Marrow Derived (BMMC) and Peritoneal (PMC) Mast Cells of TRPC-Deficient Mice
Frontiers in Immunology; Año: 2020 vol. 11
CAMACHO LONDOÑO, JUAN E.; MARX, ANDRÉ; KRAFT, AXEL E.; SCHÜRGER, ALEXANDER; RICHTER, CHRISTIN; DIETRICH, ALEXANDER; LIPP, PETER; BIRNBAUMER, LUTZ; FREICHEL, MARC
Angiotensin-II-Evoked Ca2+ Entry in Murine Cardiac Fibroblasts Does Not Depend on TRPC Channels
Cells; Año: 2020 vol. 9
PALLÉ, ANNA; MONTERO, MARTA; FERNÁNDEZ, SILVIA; TEZANOS, PATRICIA; DE LAS HERAS, JUAN A.; LUSKEY, VALERIE; BIRNBAUMER, LUTZ; ZUFALL, FRANK; CHAMERO, PABLO; TREJO, JOSÉ LUIS
Gαi2+ vomeronasal neurons govern the initial outcome of an acute social competition
Scientific Reports; Año: 2020 vol. 10
COZART, MICHAEL A.; PHELAN, KEVIN D.; WU, HONG; MU, SHENGYU; BIRNBAUMER, LUTZ; RUSCH, NANCY J.; ZHENG, FANG
Vascular smooth muscle TRPC3 channels facilitate the inverse hemodynamic response during status epilepticus
Scientific Reports; Año: 2020 vol. 10
TOMILIN, VIKTOR N.; MAMENKO, MYKOLA; ZAIKA, OLEG; REN, GUOHUI; MARRELLI, SEAN P.; BIRNBAUMER, LUTZ; POCHYNYUK, OLEH
TRPC3 determines osmosensitive [Ca2+]i signaling in the collecting duct and contributes to urinary concentration
PLOS ONE; Año: 2019 vol. 14
GREENBERG, HARRY Z.E.; CARLTON-CAREW, SIMONETTE R.E.; ZARGARAN, ALEXANDER K.; JAHAN, KAZI S.; BIRNBAUMER, LUTZ; ALBERT, ANTHONY P.
Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced relaxations and nitric oxide production in mesenteric arteries: comparative study using wild-type and TRPC1−/- mice
CHANNELS; Año: 2019 vol. 13 p. 410 - 423
CAO, QIUHUA; GAO, XINGHUA; LIN, YANTING; YUE, CHONGXIU; WANG, YUE; QUAN, FEI; ZHANG, ZIXUAN; LIU, XIAOXUAN; LU, YUAN; ZHAN, YANLING; YANG, HONGBAO; LI, XIANJING; QIN, DI; BIRNBAUMER, LUTZ; HAO, KUN; YANG, YONG
Thymopentin ameliorates dextran sulfate sodium-induced colitis by triggering the production of IL-22 in both innate and adaptive lymphocytes
Theranostics; Año: 2019 vol. 9 p. 7490 - 7505
FARMER, LOUISE K.; ROLLASON, RUTH; WHITCOMB, DANIEL J.; NI, LAN; GOODLIFF, ALEXANDER; LAY, ABIGAIL C.; BIRNBAUMER, LUTZ; HEESOM, KATE J.; XU, SHANG-ZHONG; SALEEM, MOIN A.; WELSH, GAVIN I.
TRPC6 Binds to and activates calpain, independent of its channel activity, and regulates podocyte cytoskeleton, cell adhesion, and motility
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY; Año: 2019 vol. 30 p. 1910 - 1924
CHA, HYE LIM; CHOI, JUNG-MI; OH, HUY-HYEN; BASHYAL, NARAYAN; KIM, SUNG-SOO; BIRNBAUMER, LUTZ; SUH-KIM, HAEYOUNG
Deletion of the α subunit of the heterotrimeric Go protein impairs cerebellar cortical development in mice
Molecular Brain; Año: 2019 vol. 12
NUMAGA-TOMITA, TAKURO; SHIMAUCHI, TSUKASA; ODA, SAYAKA; TANAKA, TOMOHIRO; NISHIYAMA, KAZUHIRO; NISHIMURA, AKIYUKI; BIRNBAUMER, LUTZ; MORI, YASUO; NISHIDA, MOTOHIRO
TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential-dependent coupling with PTEN
FASEB JOURNAL; Año: 2019 vol. 33 p. 9785 - 9796
EGOROV, ALEXEI V.; SCHUMACHER, DAGMAR; MEDERT, REBEKKA; BIRNBAUMER, LUTZ; FREICHEL, MARC; DRAGUHN, ANDREAS
TRPC channels are not required for graded persistent activity in entorhinal cortex neurons
HIPPOCAMPUS; Año: 2019 vol. 29 p. 1038 - 1048
TIAPKO, OLEKSANDRA; SHRESTHA, NIROJ; LINDINGER, SONJA; GUEDES DE LA CRUZ, GEMA; GRAZIANI, ANNARITA; KLEC, CHRISTIANE; BUTORAC, CARMEN; GRAIER, WOLFGANG. F.; KUBISTA, HELMUT; FREICHEL, MARC; BIRNBAUMER, LUTZ; ROMANIN, CHRISTOPH; GLASNOV, TOMA; GROSCHNER, KLAUS
Lipid-independent control of endothelial and neuronal TRPC3 channels by light
Chemical Science; Año: 2019 vol. 10 p. 2837 - 2842
IBEH, CLIFF-LAWRENCE; YIU, ALLEN J.; KANARAS, YIANNI L.; PAAL, EDINA; BIRNBAUMER, LUTZ; JOSE, PEDRO A.; BANDYOPADHYAY, BIDHAN C.
Evidence for a regulated ca2+ entry in proximal tubular cells and its implication in calcium stone formation
JOURNAL OF CELL SCIENCE; Año: 2019 vol. 132
LI, ZHI-WEI; SUN, BEICHENG; GONG, TING; GUO, SHENG; ZHANG, JIANHUA; WANG, JUNLONG; SUGAWARA, ATSUSHI; JIANG, MEISHENG; YAN, JUNJUN; GURARY, ALEXANDRA; ZHENG, XIN; GAO, BIFENG; XIAO, SHU-YUAN; CHEN, WENLIAN; MA, CHI; FARRAR, CHRISTINE; ZHU, CHENJUN; CHAN, OWEN T.M.; XIN, CAN; WINNICKI, ANDREW; WINNICKI, JOHN; TANG, MINGXIN; PARK, RYAN; WINNICKI, MARY; DIENER, KATRINA; WANG, ZHANWEI; LIU, QICAI; CHU, CATHERINE H.; ARTER, ZHAOHUI L.; YUE, PEIBIN; ALPERT, LINDSAY; HUI, GEORGE S.; FEI, PEIWEN; TURKSON, JAMES; YANG, WENTIAN; WU, GUANGYU; TAO, AILIN; RAMOS, JOE W.; MOISYADI, STEFAN; HOLCOMBE, RANDALL F.; JIA, WEI; BIRNBAUMER, LUTZ; ZHOU, XIQIAO; CHU, WEN-MING
GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2
GASTROENTEROLOGY; Año: 2019 vol. 156 p. 2297 - 2312
TROUILLET, ANNE-CHARLOTTE; KELLER, MATTHIEU; WEISS, JAN; LEINDERS-ZUFALL, TRESE; BIRNBAUMER, LUTZ; ZUFALL, FRANK; CHAMERO, PABLO
Central role of G protein Gαi2 and Gαi2 + vomeronasal neurons in balancing territorial and infant-directed aggression of male mice
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2019 vol. 116 p. 5135 - 5143
SALIBA, YOUAKIM; JEBARA, VICTOR; HAJAL, JOELLE; MAROUN, RICHARD; CHACAR, STÉPHANIE; SMAYRA, VIVIANE; ABRAMOWITZ, JOEL; BIRNBAUMER, LUTZ; FARÈS, NASSIM
Transient Receptor Potential Canonical 3 and Nuclear Factor of Activated T Cells C3 Signaling Pathway Critically Regulates Myocardial Fibrosis
ANTIOXIDANTS & REDOX SIGNALING; Año: 2019 vol. 30 p. 1851 - 1879
WU, JUN; RYSKAMP, DANIEL; BIRNBAUMER, LUTZ; BEZPROZVANNY, ILYA
Inhibition of TRPC1-Dependent Store-Operated Calcium Entry Improves Synaptic Stability and Motor Performance in a Mouse Model of Huntington’s Disease
Journal of Huntington's Disease; Año: 2018 vol. 7 p. 35 - 50
BARON, JENS; BILBAO, AINHOA; HÖRTNAGL, HEIDE; BIRNBAUMER, LUTZ; LEIXNER, SARAH; SPANAGEL, RAINER; AHNERT-HILGER, GUDRUN; BRUNK, IRENE
Balance of Go1α and Go2α expression regulates motor function via the striatal dopaminergic system
JOURNAL OF NEUROCHEMISTRY; Año: 2018 vol. 146 p. 374 - 389
YAMAGUCHI, YOHEI; IRIBE, GENTARO; KANEKO, TOSHIYUKI; TAKAHASHI, KEN; NUMAGA-TOMITA, TAKURO; NISHIDA, MOTOHIRO; BIRNBAUMER, LUTZ; NARUSE, KEIJI
TRPC3 participates in angiotensin II type 1 receptor-dependent stress-induced slow increase in intracellular Ca2+ concentration in mouse cardiomyocytes
JOURNAL OF PHYSIOLOGICAL SCIENCES; Año: 2018 vol. 68 p. 153 - 164
DUBE, PRABHATCHANDRA R.; CHIKKAMENAHALLI, LAKSHMIKANTH L.; BIRNBAUMER, LUTZ; VAZQUEZ, GUILLERMO
Reduced calcification and osteogenic features in advanced atherosclerotic plaques of mice with macrophage-specific loss of TRPC3
ATHEROSCLEROSIS; Año: 2018 vol. 270 p. 199 - 204
NOBLES, MURIEL; MONTAIGNE, DAVID; SEBASTIAN, SONIA; BIRNBAUMER, LUTZ; TINKER, ANDREW
Differential effects of inhibitory G-protein isoforms on G-protein gated inwardly rectifying K + currents in adult murine atria
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY; Año: 2018
SACHDEVA, ROBIN; SCHLOTTERER, ANDREA; SCHUMACHER, DAGMAR; MATKA, CHRISTIN; MATHAR, ILKA; DIETRICH, NADINE; MEDERT, REBEKKA; KRIEBS, ULRICH; LIN, JIHONG; NAWROTH, PETER; BIRNBAUMER, LUTZ; FLEMING, THOMAS; HAMMES, HANS-PETER; FREICHEL, MARC
TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation
Molecular Metabolism; Año: 2018 vol. 9 p. 156 - 167
MARSHALL, JOHN; ZHOU, XIAO-ZHONG; CHEN, GANG; YANG, SU-QING; LI, YA; WANG, YIN; ZHANG, ZHI-QING; JIANG, QIN; BIRNBAUMER, LUTZ; CAO, CONG
Antidepression action of BDNF requires and is mimicked by Gαi1/3 expression in the hippocampus
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2018
GAO, XINGHUA; CAO, QIUHUA; CHENG, YAN; ZHAO, DANDAN; WANG, ZHUO; YANG, HONGBAO; WU, QIJIN; YOU, LINJUN; WANG, YUE; LIN, YANTING; LI, XIANJING; WANG, YUN; BIAN, JIN-SONG; SUN, DONGDONG; KONG, LINGYI; BIRNBAUMER, LUTZ; YANG, YONG
Chronic stress promotes colitis by disturbing the gut microbiota and triggering immune system response
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2018 vol. 115 p. 2960 - 2969
ILATOVSKAYA, DARIA V.; BLASS, GREGORY; PALYGIN, OLEG; LEVCHENKO, VLADISLAV; PAVLOV, TENGIS S.; GRZYBOWSKI, MICHAEL N.; WINSOR, KRISTEN; SHUYSKIY, LEONID S.; GEURTS, ARON M.; COWLEY, ALLEN W.; BIRNBAUMER, LUTZ; STARUSCHENKO, ALEXANDER
A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY; Año: 2018 vol. 29 p. 1917 - 1927
MARCOTT, PAMELA F.; GONG, SHENG; DONTHAMSETTI, PRASHANT; GRINNELL, STEVEN G.; NELSON, MELISSA N.; NEWMAN, AMY H.; BIRNBAUMER, LUTZ; MARTEMYANOV, KIRILL A.; JAVITCH, JONATHAN A.; FORD, CHRISTOPHER P.
Regional Heterogeneity of D2-Receptor Signaling in the Dorsal Striatum and Nucleus Accumbens
NEURON; Año: 2018 vol. 98 p. 575 - 587
CHENG, YAN; GAO, XING-HUA; LI, XIAN-JING; CAO, QIU-HUA; ZHAO, DAN-DAN; ZHOU, JIN-RONG; WU, HONG-XI; WANG, YUN; YOU, LIN-JUN; YANG, HONG-BAO; HE, YUN-LONG; LI, YONG-REN; BIAN, JIN-SONG; ZHU, QING-YI; BIRNBAUMER, LUTZ; YANG, YONG
Depression promotes prostate cancer invasion and metastasis via a sympathetic-cAMP-FAK signaling pathway
ONCOGENE; Año: 2018 vol. 37 p. 2953 - 2966
HOU, XIN; XIAO, HAITAO; ZHANG, YANHONG; ZENG, XIXI; HUANG, MENGJUN; CHEN, XIAOYUN; BIRNBAUMER, LUTZ; LIAO, YANHONG
Transient receptor potential channel 6 knockdown prevents apoptosis of renal tubular epithelial cells upon oxidative stress via autophagy activation
Cell Death and Disease; Año: 2018 vol. 9
CHAUHAN, ARUN; SUN, YUYANG; SUKUMARAN, PRAMOD; QUENUM ZANGBEDE, FREDICE O.; JONDLE, CHRISTOPHER N.; SHARMA, ATUL; EVANS, DUSTIN L.; CHAUHAN, POOJA; SZLABICK, RANDOLPH E.; AALAND, MARY O.; BIRNBAUMER, LUTZ; SHARMA, JYOTIKA; SINGH, BRIJ B.; MISHRA, BIBHUTI B.
M1 Macrophage Polarization Is Dependent on TRPC1-Mediated Calcium Entry
iScience; Año: 2018 vol. 8 p. 85 - 102
CAO H1,; QADRI SM2,3, ; LANG E4,; PELZL L1, ; UMBACH AT1, ; LEISS V5,; BIRNBAUMER L6,; NÜRNBERG B5,; PIESKE B; VOELKL J; GAWAZ M11; BISSINGER R11,; LANG F
Heterotrimeric G-protein subunit Gαi2 contributes to agonist-sensitive apoptosis and degranulation in murine platelets
Physiological Reports; Año: 2018
SONODA, TAKUMA; LEE, SEUL KI; BIRNBAUMER, LUTZ; SCHMIDT, TIFFANY M.
Melanopsin Phototransduction Is Repurposed by ipRGC Subtypes to Shape the Function of Distinct Visual Circuits
NEURON; Año: 2018 vol. 99 p. 754 - 767
SHI, JIAN; MIRALLES, FRANCESC; KINET, JEAN-PIERRE; BIRNBAUMER, LUTZ; LARGE, WILLIAM A.; ALBERT, ANTHONY P.
Evidence that Orai1 does not contribute to store-operated TRPC1 channels in vascular smooth muscle cells
CHANNELS; Año: 2017 p. 1 - 11
ODA, SAYAKA; NUMAGA-TOMITA, TAKURO; KITAJIMA, NAOYUKI; TOYAMA, TAKASHI; HARADA, ERI; SHIMAUCHI, TSUKASA; NISHIMURA, AKIYUKI; ISHIKAWA, TATSUYA; KUMAGAI, YOSHITO; BIRNBAUMER, LUTZ; NISHIDA, MOTOHIRO
TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice
Scientific Reports; Año: 2017 vol. 7
HE, XIJU; LI, SHOUTIAN; LIU, BENJU; SUSPERREGUY, SEBASTIAN; FORMOSO, KARINA; YAO, JINGHONG; KANG, JINSONG; SHI, ANBING; BIRNBAUMER, LUTZ; LIAO, YANHONG
Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2017
SUN, YUYANG; ZHANG, HAOPENG; SELVARAJ, SENTHIL; SUKUMARAN, PRAMOD; LEI, SAOBO; BIRNBAUMER, LUTZ; SINGH, BRIJ B.
Inhibition of L-type Ca2+ channels by TRPC1-STIM1 complex is essential for the protection of dopaminergic neurons
JOURNAL OF NEUROSCIENCE; Año: 2017 vol. 37 p. 3364 - 3377
SOLANKI, SUMEET; DUBE, PRABHATCHANDRA R.; BIRNBAUMER, LUTZ; VAZQUEZ, GUILLERMO
Reduced Necrosis and Content of Apoptotic M1 Macrophages in Advanced Atherosclerotic Plaques of Mice With Macrophage-Specific Loss of Trpc3
Scientific Reports; Año: 2017 vol. 7
YAMAGUCHI, YOHEI; IRIBE, GENTARO; KANEKO, TOSHIYUKI; TAKAHASHI, KEN; NUMAGA-TOMITA, TAKURO; NISHIDA, MOTOHIRO; BIRNBAUMER, LUTZ; NARUSE, KEIJI
TRPC3 participates in angiotensin II type 1 receptor-dependent stress-induced slow increase in intracellular Ca2+ concentration in mouse cardiomyocytes
JOURNAL OF PHYSIOLOGICAL SCIENCES; Año: 2017 p. 1 - 12
DALTON, GEORGE; AN, SUNG-WAN; AL-JUBOORI, SAIF I.; NISCHAN, NICOLE; YOON, JOONHO; DOBRINSKIKH, EVGENIA; HILGEMANN, DONALD W.; XIE, JIAN; LUBY-PHELPS, KATE; KOHLER, JENNIFER J.; BIRNBAUMER, LUTZ; HUANG, CHOU-LONG
Soluble klotho binds monosialoganglioside to regulate membrane microdomains and growth factor signaling
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2017 vol. 114 p. 752 - 757
KUMARASAMY, SIVARAJAN; SOLANKI, SUMEET; ATOLAGBE, OLUWATOMISIN T.; JOE, BINA; BIRNBAUMER, LUTZ; VAZQUEZ, GUILLERMO
Deep Transcriptomic Profiling of M1 Macrophages Lacking Trpc3
Scientific Reports; Año: 2017 vol. 7
PHELAN, KEVIN D.; SHWE, U THAUNG; COZART, MICHAEL A.; WU, HONG; MOCK, MATTHEW M.; ABRAMOWITZ, JOEL; BIRNBAUMER, LUTZ; ZHENG, FANG
TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice
EPILEPSIA; Año: 2017 vol. 58 p. 247 - 254
WU, YUEH-LIN; XIE, JIAN; AN, SUNG-WAN; OLIVER, NOELYNN; BARREZUETA, NESTOR X.; LIN, MEI-HSIANG; BIRNBAUMER, LUTZ; HUANG, CHOU-LONG
Inhibition of TRPC6 channels ameliorates renal fibrosis and contributes to renal protection by soluble klotho
KIDNEY INTERNATIONAL; Año: 2017 vol. 91 p. 830 - 841
CHRÉTIEN, CHLOÉ; FENECH, CLAIRE; LIÉNARD, FABIENNE; GRALL, SYLVIE; CHEVALIER, CHARLÈNE; CHAUDY, SYLVIE; BRENACHOT, XAVIER; BERGES, RAYMOND; LOUCHE, KATIE; STARK, ROMANA; NÉDÉLEC, EMMANUELLE; LADERRIÈRE, AMÉLIE; ANDREWS, ZANE B.; BENANI, ALEXANDRE; FLOCKERZI, VEIT; GASCUEL, JEAN; HARTMANN, JANA; MORO, CÉDRIC; BIRNBAUMER, LUTZ; LELOUP, CORINNE; PÉNICAUD, LUC; FIORAMONTI, XAVIER
Transient receptor potential canonical 3 (TRPC3) channels are required for hypothalamic glucose detection and energy homeostasis
DIABETES; Año: 2017 vol. 66 p. 314 - 324
SHI, JIAN; MIRALLES, FRANCESC; BIRNBAUMER, LUTZ; LARGE, WILLIAM A.; ALBERT, ANTHONY P.
Store-operated interactions between plasmalemmal STIM1 and TRPC1 proteins stimulate PLCβ1 to induce TRPC1 channel activation in vascular smooth muscle cells
THE JOURNAL OF PHYSIOLOGY; Año: 2017 vol. 595 p. 1039 - 1058
DUBE, PRABHATCHANDRA R.; BIRNBAUMER, LUTZ; VAZQUEZ, GUILLERMO
Evidence for constitutive bone morphogenetic protein-2 secretion by M1 macrophages: Constitutive auto/paracrine osteogenic signaling by BMP-2 in M1 macrophages
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 2017 vol. 491 p. 154 - 158
DANIELCZOK, JENS; HERTZ, LAURA; RUPPENTHAL, SANDRA; KAISER, ELISABETH; PETKOVA-KIROVA, POLINA; BOGDANOVA, ANNA; KRAUSE, ELMAR; LIPP, PETER; FREICHEL, MARC; KAESTNER, LARS; BIRNBAUMER, LUTZ
Does Erythropoietin Regulate TRPC Channels in Red Blood Cells?
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY : INTERNATIONAL JOURNAL OF EXPERIMENTAL CELLULAR PHYSIOLOGY, BIOCHEMISTRY, AND PHARMACOLOGY.; Año: 2017 vol. 41 p. 1219 - 1228
LI, WEIZU; DING, YANFENG; SMEDLEY, CRYSTAL; WANG, YANXIA; CHAUDHARI, SARIKA; BIRNBAUMER, LUTZ; MA, RONG
Increased glomerular filtration rate and impaired contractile function of mesangial cells in TRPC6 knockout mice
Scientific Reports; Lugar: New York; Año: 2017 vol. 7
BELKACEMI, THABET; NIERMANN, ALEXANDER; HOFMANN, LAURA; WISSENBACH, ULRICH; BIRNBAUMER, LUTZ; LEIDINGER, PETRA; BACKES, CHRISTINA; MEESE, ECKART; KELLER, ANDREAS; BAI, XIANSHU; SCHELLER, ANJA; KIRCHHOFF, FRANK; PHILIPP, STEPHAN E.; WEISSGERBER, PETRA; FLOCKERZI, VEIT; BECK, ANDREAS
TRPC1- and TRPC3-dependent Ca2+ signaling in mouse cortical astrocytes affects injury-evoked astrogliosis in vivo
GLIA; Lugar: New York; Año: 2017
BENJU LIU; XIJU HE; SHOUTIAN LI; BENKE XU; LUTZ BIRNBAUMER; YANHONG LIAO
Deletion of diacylglycerol-responsive TRPC genes attenuates diabetic nephropathy by inhibiting activation of the TGFβ1 signaling pathway
American Journal of Translational Research; Año: 2017
CHAUDHURI, PINAKI; ROSENBAUM, MICHAEL A.; BIRNBAUMER, LUTZ; GRAHAM, LINDA M.
Integration of TRPC6 and NADPH oxidase activation in lysophosphatidylcholine-induced TRPC5 externalization
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY; Año: 2017 vol. 313 p. 541 - 555
CHEN, XIAOYUN; LU, MIN; HE, XIJU; MA, LE; BIRNBAUMER, LUTZ; LIAO, YANHONG
TRPC3/6/7 Knockdown Protects the Brain from Cerebral Ischemia Injury via Astrocyte Apoptosis Inhibition and Effects on NF-кB Translocation
MOLECULAR NEUROBIOLOGY; Año: 2017 vol. 54 p. 7555 - 7566
WOOD JN; SEXTON JE; DESMONDS T; BIRNBAUMER L
The contribution of TRPC1, TRPC3, TRPC5 and TRPC6 to touch and hearing.
NEUROSCIENCE LETTERS; Lugar: Amsterdam; Año: 2016
CHAUDHURI P; ROSENBAUM MA; BIRNBAUMER L,; GRAHAM LM
Membrane translocation of TRPC6 channels and endothelial migration are regulated by calmodulin and PI3 kinase activation
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2016
SHI, JIAN; MIRALLES, FRANCESC; BIRNBAUMER, LUTZ; LARGE, WILLIAM A.; ALBERT, ANTHONY P.
Storedepletion induces Galphaq-mediated PLCbeta1 activity to stimulate TRPC1 channels in vascular smooth muscle cells
FASEB JOURNAL; Año: 2016 vol. 30 p. 702 - 715
BISSINGER, ROSI; LANG, ELISABETH; GHASHGHAEINIA, MEHRDAD; SINGH, YOGESH; ZELENAK, CHRISTINE; FEHRENBACHER, BIRGIT; HONISCH, SABINA; CHEN, HONG; FAKHRI, HAJAR; UMBACH, ANJA T.; LIU, GUILAI; REXHEPAJ, REXHEP; LIU, GUOXING; SCHALLER, MARTIN; MACK, ANDREAS F.; LUPESCU, ADRIAN; BIRNBAUMER, LUTZ; LANG, FLORIAN; QADRI, SYED M.
Blunted apoptosis of erythrocytes in mice deficient in the heterotrimeric G-protein subunit Galphai2.
Scientific Reports; Año: 2016 vol. 6
CHEN, XIAOYUN; LU, MIN; HE, XIJU; MA, LE; BIRNBAUMER, LUTZ; LIAO, YANHONG
TRPC3/6/7 Knockdown Protects the Brain from Cerebral Ischemia Injury via Astrocyte Apoptosis Inhibition and Effects on NF-kB Translocation
MOLECULAR NEUROBIOLOGY; Lugar: New York; Año: 2016 p. 1 - 12
XU Y; ORLANDI C; VARDI N; BIRNBAUMER L
The TRPM1 channel in ON-bipolar cells is gated by both the alpha; and the beta-gamma subunits of the G-protein Go
SCIENTIFIC RESEARCH AND ESSAYS; Lugar: New York; Año: 2016
SHI J; MIRALLES F; BIRNBAUMER L,; ALBERT AP
Store depletion induces Galphaq-mediated PLCbeta1 activityto stimulate TRPC1 channels in vascular smooth muscle cells
FASEB JOURNAL; Lugar: Bethesda; Año: 2016
KITAJIMA, NAOYUKI; NUMAGA-TOMITA, TAKURO; WATANABE, MASAHIKO; KURODA, TAKUYA; NISHIMURA, AKIYUKI; MIYANO, KEI; YASUDA, SATOSHI; KUWAHARA, KOICHIRO; SATO, YOJI; IDE, TOMOMI; BIRNBAUMER, LUTZ; SUMIMOTO, HIDEKI; MORI, YASUO; NISHIDA, MOTOHIRO
TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling
Scientific Reports; Lugar: London; Año: 2016 vol. 6
NUMAGA-TOMITA, TAKURO; KITAJIMA, NAOYUKI; KURODA, TAKUYA; NISHIMURA, AKIYUKI; MIYANO, KEI; YASUDA, SATOSHI; KUWAHARA, KOICHIRO; SATO, YOJI; IDE, TOMOMI; BIRNBAUMER, LUTZ; SUMIMOTO, HIDEKI; MORI, YASUO; NISHIDA, MOTOHIRO
TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis
Scientific Reports; Año: 2016 vol. 6
CHOI, JUNG-MI; KIM, SUNG-SOO; CHOI, CHAN-IL; LIM, HYE; OH, HUY-HYEN; GHIL, SUNGHO; LEE, YOUNG-DON; BIRNBAUMER, LUTZ; SUH-KIM, HAEYOUNG
Development of the main olfactory system and main olfactory epithelium-dependent male mating behavior are altered in Go -deficient mice
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2016 vol. 113 p. 10974 - 10979
HAN, JUNG WOO; LEE, YOUNG HO; YOEN, SU-IN; ABRAMOWITZ, JOEL; BIRNBAUMER, LUTZ; LEE, MIN GOO; KIM, JOO YOUNG
Resistance to pathologic cardiac hypertrophy and reduced expression of CaV1.2 in Trpc3-depleted mice
MOLECULAR AND CELLULAR BIOCHEMISTRY; Año: 2016 vol. 421 p. 55 - 65
BIRNBAUMER, LUTZ
From GTP and G proteins to TRPC channels: a personal account
JOURNAL OF MOLECULAR MEDICINE (BERLIN, GERMANY); Lugar: Berlin; Año: 2016 vol. 93 p. 941 - 953
KELLER K; MATTHES J; BIRNBAUMER L,; ANNALA S
Lack of Gαi2 leads to dilative cardiomyopathy and increased mortality in β1-adrenoceptor overexpressing mice
CARDIOVASCULAR RESEARCH; Lugar: Oxford; Año: 2015
NEUNER SM; WILMOTT LA; HOPE KA; HOFFMANN B; CHONG JA; ABRAMOWITZ J; BIRNBAUMER L; O'CONNELL KM; SAVIO CHAN C; KACZOROWSKI CC.
TRPC3 channels critically regulate hippocampal excitability and contextual fear memory.
BEHAVIOURAL BRAIN RESEARCH; Lugar: Amsterdam; Año: 2015
SMEDLUND KB; BIRNBAUMER L; VAZQUEZ G.
Increased size and cellularity of advanced atherosclerotic lesions in mice with endothelial overexpression of the human TRPC3 channel.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2015
LI X; WANG D; CHEN Z; LU E; BIRNBAUMER L; YANG Y.
Galphai1 and Galphai3 regulate macrophage polarization by forming a complex containing CD14 and Gab1.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2015
SUN Y; BIRNBAUMER L; SINGH BB.
TRPC1 Regulates Calcium-Activated Chloride Channels in Salivary Gland Cells.
JOURNAL OF CELLULAR PHYSIOLOGY; Lugar: New York; Año: 2015
WEBER EW; MULLER WA; BIRNBAUMER L; HAN F
TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response
JOURNAL OF EXPERIMENTAL MEDICINE; Lugar: New York; Año: 2015
BIRNBAUMER L,
From GTP and G proteins to TRPC channels: a personal account
JOURNAL OF MOLECULAR MEDICINE (BERLIN, GERMANY); Lugar: Berlin; Año: 2015
VILLANUEVA H; LEWIS MT; PLUMMER NW; BIRNBAUMER L
An essential role for Gα(i2) in Smoothened-stimulated epithelial cell proliferation in the mammary gland
SCIENCE SIGNALING; Año: 2015
PÉREZ-GÓMEZ A; BLEYMEHL K; BIRNBAUMER L; MUNGER SD
Innate Predator Odor Aversion Driven by Parallel Olfactory Subsystems that Converge in the Ventromedial Hypothalamus
CURRENT BIOLOGY; Lugar: United States; Año: 2015
LIPP P; CAMACHO LONDOÑO JE; TIAN Q; BIRNBAUMER L
A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling
EUROPEAN HEART JOURNAL; Lugar: Oxford; Año: 2015
DEVANATHAN V; NÜRNBERG B; BIRNBAUMER L
Platelet Gi protein Gαi2 is an essential mediator of thrombo-inflammatory organ damage in mice.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2015
SUN, YUYANG; BIRNBAUMER, LUTZ; SINGH, BRIJ B.
TRPC1 regulates calcium-activated chloride channels in salivary gland cells
JOURNAL OF CELLULAR PHYSIOLOGY; Año: 2015 vol. 230 p. 2848 - 2856
PÉREZ-GÓMEZ, ANABEL; BLEYMEHL, KATHERIN; STEIN, BENJAMIN; PYRSKI, MARTINA; BIRNBAUMER, LUTZ; MUNGER, STEVEN D.; LEINDERS-ZUFALL, TRESE; ZUFALL, FRANK; CHAMERO, PABLO
Innate predator odor aversion driven by parallel olfactory subsystems that converge in the ventromedial hypothalamus
CURRENT BIOLOGY; Año: 2015 vol. 25 p. 1340 - 1346
ZHOU, XIKUN; YE, YAN; SUN, YUYANG; LI, XUEFENG; WANG, WENXUE; PRIVRATSKY, BREANNA; TAN, SHIRUI; ZHOU, ZONGGUANG; HUANG, CANHUA; WEI, YU-QUAN; BIRNBAUMER, LUTZ; SINGH, BRIJ B.; WU, MIN
Transient receptor potential channel 1 deficiency impairs host defense and proinflammatory responses to bacterial infection by regulating protein kinase Cα signaling
MOLECULAR AND CELLULAR BIOLOGY; Año: 2015 vol. 35 p. 2729 - 2739
RIAZANSKI V; GABDOULKHAKOVA AG; BIRNBAUMER L,; NELSON DJ
TRPC6 channel translocation into phagosomal membrane augments phagosomal function.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2015
KELLER, KIRSTEN; MAASS, MARTINA; DIZAYEE, SARA; LEISS, VERONIKA; ANNALA, SUVI; KÖTH, JESSICA; SEEMANN, WIEBKE K.; MÜLLER-EHMSEN, JOCHEN; MOHR, KLAUS; NÜRNBERG, BERND; ENGELHARDT, STEFAN; HERZIG, STEFAN; BIRNBAUMER, LUTZ; MATTHES, JAN
Lack of Gαi2 leads to dilative cardiomyopathy and increased mortality in β1-adrenoceptor overexpressing mice
CARDIOVASCULAR RESEARCH; Año: 2015 vol. 108 p. 348 - 356
OBOTI L; PÉREZ-GÓMEZ A; KELLER M; JACOBI E; BIRNBAUMER L; LEINDERS-ZUFALL T; ZUFALL F; CHAMERO P
A wide range of pheromone-stimulated sexual and reproductive behaviors in female mice depend on G protein Galfa-o
BMC BIOLOGY; Lugar: Londres; Año: 2014
MINETTI GC; FEIGE JN; BOMBARD F; HEIER A; MORVAN F; NÜRNBERG B.; LEISS V; BIRNBAUMER L; GLASS DJ; FORNARO M
Galfa-i2 signaling is required for skeletal muscle growth, regeneration, and satellite cell proliferation and differentiation.
MOLECULAR AND CELLULAR BIOLOGY; Lugar: Washington; Año: 2014
KINYA SEO; PETER P. RAINER ; VIRGINIA SHALKEY HAHN; DONG-IK LEE; SU-HYUN JO; ASGER ANDERSEN; TING LIU; XIAOPING XU; ROBERT N. WILLETTE; JOHN J. LEPORE; JOSEPH P. MARINO, J; LUTZ BIRNBAUMER; CHRISTINE G. SCHNACKENBERG; DAVID A. KASS
Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2014
KINYA SEO ; PETER P RAINER; DONG I LEE; SCARLETT HAO; DJAHIDA BEDJA; LUTZ BIRNBAUMER; OSCAR H CINGOLANI; DAVID A KASS
yperactive Adverse Mechanical-Stress Responses in Dystrophic Heart are Coupled to TRPC6 and Blocked by cGMP-PKG Modulation
CIRCULATION RESEARCH; Lugar: Philadelphia; Año: 2014
ZHANWEI WANG; RICA DELA CRUZ; FANG JI; SHENG GUO; JIANHUA ZHANG; GEN-SHENG FENG; LUTZ BIRNBAUMER; MEISHENG JIANG; WEN-MING CHU
Gi-alfa proteins exhibit functional differences in the activation of ERK1/2, Akt and mTORC1 by growth factors in normal and breast cancer cells
CELL COMMUNICATION AND SIGNALING; Lugar: Londres; Año: 2014
CHRISTOPHER B. BALL; KARINA F. RODRIGUEZ; DEBORAH J. STUMPO; FERNANDO RIBEIRO-NETO ; KENNETH S. KORACH ; PERRY J. BLACKSHEAR; LUTZ BIRNBAUMER; SILVIA B. V. R
The RNA-Binding Protein, ZFP36L2, Influences Ovulation and Oocyte Maturation
PLOS ONE; Lugar: San Francisco; Año: 2014
SOLANKI S; DUBE PR,; TANO JY; BIRNBAUMER L, ; VAZQUEZ G.
Reduced endoplasmic reticulum stress-induced apoptosis and impaired unfolded protein response in TRPC3-deficient M1 macrophages.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY; Lugar: Bethesda; Año: 2014
PHELAN KD BIRNBAUMER L; SHWE UT; ABRAMOWITZ J; BIRNBAUMER L; ZHENG F.
Critical role of canonical transient receptor potential channel 7 in initiation of seizures.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2014
DU J; MA X; SHEN B; HUANG Y; BIRNBAUMER L; YAO X.
TRPV4, TRPC1, and TRPP2 assemble to form a flow-sensitive heteromeric channel.
FASEB JOURNAL; Lugar: Bethesda; Año: 2014
KOCHUKOV MY; BALASUBRAMANIAN A; ABRAMOWITZ J; BIRNBAUMER L; MARRELLI SP.
Activation of endothelial transient receptor potential C3 channel is required for small conductance calcium-activated potassium channel activation and sustained endothelial hyperpolarization and vasodilation of cerebral artery.
Journal of the American Heart Association; Año: 2014
LEISS V; FLOCKERZIE K,; NOVAKOVIC A; RATH M; SCHÖNSIEGEL A; BIRNBAUMER L; SCHÜRMANN A; HARTENECK C; NÜRNBERG B.
Insulin secretion stimulated by L-arginine and its metabolite L-ornithine depends on Gα(i2).
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM; Lugar: Bethesda; Año: 2014
YEON SI; KIM JY; YEON DS; ABRAMOWITZ J; BIRNBAUMER L; MUALLEM S; LEE YH.
Transient receptor potential canonical type 3 channels control the vascular contractility of mouse mesenteric arteries. Yeon SI, Kim JY, Yeon DS, Abramowitz J, Birnbaumer L, Muallem S, Lee YH.
PLOS ONE; Lugar: San Francisco; Año: 2014
LUTAS A; BIRNBAUMER L; YELLEN G.
Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels.
JOURNAL OF NEUROSCIENCE; Lugar: Washington; Año: 2014
SALIBA Y; KARAM R; SMAYRA V; AFTIMOS G; ABRAMOWITZ J; BIRNBAUMER L; FARÈS N.
Evidence of a Role for Fibroblast Transient Receptor Potential Canonical 3 Ca2+ Channel in Renal Fibrosis.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY; Año: 2014
DOMES K; PATRUCCO E; LOGA F; DIETRICH A; BIRNBAUMER L; WEGENER JW; HOFMANN F
Murine cardiac growth, TRPC channels, and cGMP kinase I.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY; Lugar: Berlin; Año: 2014
DAVID KOHLER ; VASUDHARANI DEVANATHAN; CLAUDIA BERNARDO DE OLIVEIRA FRANZ; THERESE ELDH; ANA NOVAKOVIC; JUDITH M. ROTH ; TIAGO GRANJA; LUTZ BIRNBAUMER ; PETER ROSENBERGER; SANDRA BEERHAMMER; BERND NURNBERG
Gai2- and Gai3-Deficient Mice Display Opposite Severity of Myocardial Ischemia Reperfusion Injury
PLOS ONE; Lugar: San Francisco; Año: 2014
CHAN-IL CHOI ; SANG-PHIL YOON ; JUNG-MI CHOI; SUNG-SOO KIM ; YOUNG-DON LEE; LUTZ BIRNBAUMER ; HAEYOUNG SUH-KIM
Simultaneous deletion of floxed genes mediated by CaMKIIa-Cre in the brain and in male germ cells: application to conditional and conventional disruption of Go-alfa
EXPERIMENTAL AND MOLECULAR MEDICINE EMM; Año: 2014
DARIA V. ILATOVSKAYA; OLEG PALYGIN; VLADISLAV CHUBINSKIY-NADEZHDIN; YURI A. NEGULYAEV; RONG MA; LUTZ BIRNBAUMER; ALEXANDER STARUSCHEN
Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli
KIDNEY INTERNATIONAL; Lugar: Londres; Año: 2014
DASARI S; BIRNBAUMER L,; ABRAMOWITZ J; GULLEDGE AT
Do canonical transient receptor potential channels mediate cholinergic excitation of cortical pyramidal neurons?
NEUROREPORT; Lugar: Philadelphia; Año: 2013
PHELAN KD ; BIRNBAUMER L,; ZHENG F.; GOTTSCHALL PE
Canonical Transient Receptor Channel 5 (TRPC5) and TRPC1/4 Contribute to Seizure and Excitotoxicity by Distinct Cellular Mechanisms
MOLECULAR PHARMACOLOGY; Lugar: Baltimore; Año: 2013
MEDIC N; BIRNBAUMER L,; DESAI A; METCALFE DD
Knockout of the Trpc1 gene reveals that TRPC1 can promote recovery from anaphylaxis by negatively regulating mast cell TNF- production
CELL CALCIUM.; Lugar: ESCOCIA; Año: 2013
FENG S; BIRNBAUMER L,; HUANG J; WANG Y
Canonical transient receptor potential 3 channels regulate mitochondrial calcium uptake
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2013
BOUDES M; BIRNBAUMER L,; PINTO S; VENNEKENS R
Crucial role of TRPC1 and TRPC4 in cystitis-induced neuronal sprouting and bladder overactivity
PLOS ONE; Lugar: San Francisco; Año: 2013
LOGA F; BIRNBAUMER L,; DOMES K; WEGENER JW
The role of cGMP/cGKI signalling and Trpc channels in regulation of vascular tone
CARDIOVASCULAR RESEARCH; Lugar: Oxford; Año: 2013
SEBASTIAN S; TINKER A; BIRNBAUMER L,; ANG R
The in-vivo regulation of heart rate in the murine sinoatrial node by stimulatory and inhibitory heterotrimeric G-proteins
THE AMERICAN JOURNAL OF PHYSIOLOGY.; Lugar: Bethesda; Año: 2013
SEKERKOVÁ G; LUTZ BIRNBAUMER; KIM JA; MARTINA M
Early onset of ataxia in moonwalker mice is accompanied by complete ablation of type II unipolar brush cells and Purkinje cell dysfunction
JOURNAL OF NEUROSCIENCE; Lugar: Washington; Año: 2013
ONG EC; TSIOKAS L; NESIN V; BIRNBAUMER L,
A TRPC1 protein-dependent pathway regulates osteoclast formation and function
JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda, Maryland; Año: 2013
YEO M; BERGLUND K; BIRNBAUMER L,; LIEDTKE WB
Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2013
HARPER MT; BIRNBAUMER L,; LONDOÑO JE; POOLE AW
Transient Receptor Potential Channels Function as a Coincidence Signal Detector Mediating Phosphatidylserine Exposure
SCIENCE SIGNALING; Año: 2013
BLEX C; LUTZ BIRNBAUMER ; BARON J; BRUNK I
The α-subunit of the trimeric GTPase Go2 regulates axonal growth
JOURNAL OF NEUROCHEMISTRY; Lugar: Londres; Año: 2013
WONG AC; HOUSLEY GD.; BIRNBAUMER L,
Canonical transient receptor potential channel subtype 3-mediated hair cell Ca(2+) entry regulates sound transduction and auditory neurotransmission
EUROPEAN JOURNAL OF NEUROSCIENCE; Lugar: Londres; Año: 2013
