FOTINÓS, JERÓNIMO; MARKS, MARÍA PAULA; BARBERIS, LUCAS; VELLÓN, LUCIANO

Assessing the distribution of cancer stem cells in tumorspheres

Scientific Reports; Año: 2024 vol. 14

GIORELLO, MARÍA BELÉN; MARKS, MARÍA PAULA; OSINALDE, TIAGO MARTÍN; PADIN, MARÍA DEL ROSARIO; WERNICKE, ALEJANDRA; CALVO, JUAN CARLOS; CHASSEING, NORMA ALEJANDRA; VELLÓN, LUCIANO

Post-surgery statin use contributes to favorable outcomes in patients with early breast cancer

CANCER EPIDEMIOLOGY; Año: 2024 vol. 90

MARKS, MARÍA PAULA; GIMÉNEZ, CARLA ALEJANDRA; ISAJA, LUCIANA; VERA, MARIANA BELÉN; BORZONE, FRANCISCO RAÚL; PEREYRA-BONNET, FEDERICO; ROMORINI, LEONARDO; VIDELA-RICHARDSON, GUILLERMO AGUSTÍN; CHASSEING, NORMA ALEJANDRA; CALVO, JUAN CARLOS; VELLÓN, LUCIANO

Role of hydroxymethylglutharyl-coenzyme A reductase in the induction of stem-like states in breast cancer

Journal of Cancer Research and Clinical Oncology; Año: 2024 vol. 150

RODRIGUEZ, MARÍA JIMENA; PERRONE, MARÍA CECILIA; RIGGIO, MARINA; PALAFOX, MARTA; SALINAS, VALERIA; ELIA, ANDRÉS; SALGUEIRO, NATALI DAIANA; WERBACH, ANDREA EUGENIA; MARKS, MARÍA PAULA; KAUFFMAN, MARCELO A.; VELLÓN, LUCIANO; SERRA, VIOLETA; NOVARO, VIRGINIA

Targeting mTOR to overcome resistance to hormone and CDK4/6 inhibitors in ER-positive breast cancer models

Scientific Reports; Año: 2023 vol. 13

ESPINOZA, INGRID; YANG, LIN; STEEN, TRAVIS VANDER; VELLON, LUCIANO; CUYÀS, ELISABET; VERDURA, SARA; LAU, LESTER; MENENDEZ, JAVIER A.; LUPU, RUTH

Binding of the angiogenic/senescence inducer CCN1/CYR61 to integrin α6β1 drives endocrine resistance in breast cancer cells

Aging; Año: 2022 vol. 14 p. 1200 - 1213

MENENDEZ, JAVIER A.; PAPADIMITROPOULOU, ADRIANA; STEEN, TRAVIS VANDER; CUYÀS, ELISABET; OZA-GAJERA, BHARVI P.; VERDURA, SARA; ESPINOZA, INGRID; VELLON, LUCIANO; MEHMI, INDERJIT; LUPU, RUTH

Fatty acid synthase confers tamoxifen resistance to er+/her2+ breast cancer

Cancers; Año: 2021 vol. 13 p. 1 - 19

BENÍTEZ, LUCÍA; BARBERIS, LUCAS; VELLÓN, LUCIANO; CONDAT, CARLOS A.

Understanding the influence of substrate when growing tumorspheres

BMC CANCER; Año: 2021 vol. 21

MENENDEZ, JAVIER A.; PEIRCE, SUSAN K.; PAPADIMITROPOULOU, ADRIANA; CUYÀS, ELISABET; STEEN, TRAVIS VANDER; VERDURA, SARA; VELLON, LUCIANO; CHEN, WEN Y.; LUPU, RUTH

Progesterone receptor isoform-dependent cross-talk between prolactin and fatty acid synthase in breast cancer

Aging; Lugar: New York; Año: 2020 vol. 12 p. 24671 - 24692

PAPADIMITROPOULOU, ADRIANA; VELLON, LUCIANO; ATLAS, ELLA; STEEN, TRAVIS VANDER; CUYÀS, ELISABET; VERDURA, SARA; ESPINOZA, INGRID; MENENDEZ, JAVIER A.; LUPU, RUTH

Heregulin drives endocrine resistance by altering il-8 expression in er-positive breast cancer

International Journal of Molecular Sciences; Año: 2020 vol. 21 p. 1 - 15

MENENDEZ, JAVIER A.; MEHMI, INDERJIT; PAPADIMITROPOULOU, ADRIANA; STEEN, TRAVIS VANDER; CUYÀS, ELISABET; VERDURA, SARA; ESPINOZA, INGRID; VELLON, LUCIANO; ATLAS, ELLA; LUPU, RUTH

Fatty acid synthase is a key enabler for endocrine resistance in heregulin-overexpressing luminal b-like breast cancer

International Journal of Molecular Sciences; Año: 2020 vol. 21 p. 1 - 14

LI, YUJING; PARK, CHANGWON; JIANG, HONG; LI, XUEKUN; VELLÓN, LUCIANO

Noncoding RNAs and Base Modifications: Epigenomic Players Implicated in Neurological Disorders and Tumorigenesis

International Journal of Genomics; Año: 2018 vol. 2018

VERDURA, SARA; CUYÀS, ELISABET; LOZANO-SÁNCHEZ, JESÚS; BASTIDAS-VELEZ, CRISTIAN; LLORACH-PARÉS, LAURA; FERNÁNDEZ-ARROYO, SALVADOR; HERNÁNDEZ-AGUILERA, ANNA; JOVEN, JORGE; NONELL-CANALS, ALFONS; BOSCH-BARRERA, JOAQUIM; MARTIN-CASTILLO, BEGOÑA; VELLON, LUCIANO; SANCHEZ-MARTINEZ, MELCHOR; SEGURA-CARRETERO, ANTONIO; MENENDEZ, JAVIER A

An olive oil phenolic is a new chemotype of mutant isocitrate dehydrogenase 1 (IDH1) inhibitors

CARCINOGENESIS; Año: 2018

COROMINAS-FAJA B; VELLÓN L; CUYÁS E; BUXÓ M ; MARTÍN-CASTILLO B; SERRA D; GARCÍA J; MENENDEZ JA; LUPU R

Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer.

HISTOLOGY AND HISTOPATHOLOGY; Lugar: Madrid; Año: 2017

MENENDEZ JA; VELLÓN L; ESPINOZA I; LUPU R

The metastasis inducer CCN1 (CYR61) activates the fatty acid synthase (FASN)-driven lipogenic phenotype in breast cancer cells.

Oncoscience; Año: 2016 vol. 3 p. 242 - 257

LI Y; PARK C; VELLÓN L; LI X

iPSCs: From Bench to Clinical Bed

Stem Cells International; Año: 2016

MENENDEZ JA; BENBOUDJEMA L; VELLÓN L; RUBIO MA; ESPINOZA I; CAMPISI J; LUPU R

Heregulin, a new interactor of the telosome/shelterin complex in human telomeres

Oncotarget; Año: 2015 vol. 6 p. 39408 - 39421

MENENDEZ JA; SCHOEDER B; PEIRCE SK; VELLÓN L; PAPADIMITROPOULOU A; ESPINOZA I; LUPU R

Blockade of a Key Region in the Extracellular Domain Inhibits HER2 Dimerization and Signaling.

JOURNAL OF THE NATIONAL CANCER INSTITUTE.; Lugar: Oxford; Año: 2015 vol. 107

MENENDEZ JA; ALARCON T; COROMINAS-FAJA B; CUYÁS E; LOPEZ-BONET E; GARCÍA-MARTÍN A; VELLON L

Xenopatients 2.0: reprogramming the epigenetic landscapes of patient-derived cancer genomes.

CELL CYCLE; Lugar: Austin, Texas; Año: 2014 vol. 13 p. 358 - 370

VAZQUEZ MARTIN A; CUFÍ S; LOPEZ-BONET E; COROMINAS-FAJA B; CUYÁS E; VELLÓN L; IGLESIAS JM; LEIS O; GARCÍA-MARTÍN A; MENENDEZ JA

Reprogramming of non-genomic estrogen signaling by the stemness factor SOX2 enhances the tumor-initiating capacity of breast cancer cells.

CELL CYCLE; Lugar: Austin, Texas; Año: 2013 vol. 12 p. 3471 - 3477

COROMINAS-FAJA B; CUFÍ S; OLIVERAS-FERRARÓS C; CUYÁS E; LOPEZ-BONET E; LUPU R; ALARCON T; VELLON L; IGLESIAS JM; LEIS O; GARCÍA-MARTÍN A; VAZQUEZ-MARTIN A; MENENDEZ JA

Nuclear reprogramming of luminal-like breast cancer cells generates Sox2-overexpressing cancer stem-like cellular states harboring transcriptional activation of the mTOR pathway.

CELL CYCLE; Lugar: Austin, Texas; Año: 2013 vol. 12 p. 3109 - 3124

MANTEROLA L; HERNANDO-RODRÍGUEZ M; RUIZ A; APRAIZ A; ARRIZABALAGA O; VELLÓN L; ALBERDI E; CAVALIERE E; LACERDA HM; JIMENEZ S; PARADA LA; MATUTE C; ZUGAZA JL

1-42 beta-Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death

TRANSLATIONAL PSYCHIATRY; Lugar: Londres; Año: 2013 vol. 3 p. 1 - 11

VÁZQUEZ-MARTÍN A; COROMINAS-FAJA B; CUFÍ S; VELLÓN L; OLIVERAS-FERRARÓS C; MENENDEZ OJ; JOVEN J; LUPU R; MENENDEZ JA

The mitochondrial H (+) -ATP synthase and the lipogenic switch: New core components of metabolic reprogramming in induced pluripotent stem (iPS) cells.

CELL CYCLE; Lugar: Austin, Texas; Año: 2013 vol. 12 p. 207 - 218

VÁZQUEZ-MARTÍN A; CUFÍ S; COROMINAS-FAJA B; OLIVERAS-FERRARÓS C; VELLÓN L; MENENDEZ JA

Mitochondrial fusion by pharmacological manipulation impedes somatic cell reprogramming to pluripotency: new insight into the role of mitophagy in cell stemness.

Aging; Año: 2012 vol. 4 p. 393 - 401

CUFÍ S; VÁZQUEZ-MARTÍN A; OLIVERAS-FERRARÓS C; QUIRANTES R; SEGURA-CARRETERO A; MICOL V; JOVEN J; BOSCH-BARRERA J; DEL BARCO S; MARTÍN-CASTILLO B; VELLÓN L; MENENDEZ JA

Metformin lowers the threshold for stress-induced senescence: a role for the microRNA-200 family and miR-205.

CELL CYCLE; Lugar: Austin, Texas; Año: 2012 vol. 11 p. 1235 - 1246

VÁZQUEZ-MARTÍN A; VELLÓN L; QUIRÓS PM; CUFÍ S; RUIZ DE GALARRETA E; OLIVERAS-FERRARÓS C; GARCÍA-MARTÍN A; MARTÍN-CASTILLO B; LÓPEZ-OTÍN C; MENENDEZ JA

Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells.

CELL CYCLE; Lugar: Austin, Texas; Año: 2012 vol. 11 p. 974 - 989

VÁZQUEZ-MARTÍN A; FERNÁNDEZ-ARROYO S; CUFÍ S; OLIVERAS-FERRARÓS C; LOZANO-SÁNCHEZ J; VELLÓN L; MICOL V; JOVEN J; SEGURA-CARRETERO A; MENENDEZ JA

Phenolic secoiridoids in extra virgin olive oil impede fibrogenic and oncogenic epithelial-to-mesenchymal transition: extra virgin olive oil as a source of novel antiaging phytochemicals.

REJUVENATION RESEARCH; Lugar: New York; Año: 2012 vol. 15 p. 3 - 21

MENENDEZ JA; CUFÍ S; OLIVERAS-FERRARÓS C; VELLÓN L; JOVEN J; VAZQUEZ-MARTÍN A

Gerosuppressant metformin: less is more.

Aging; Año: 2011 vol. 3 p. 348 - 362

MENENDEZ JA; VELLÓN L; OLIVERAS-FERRARÓS C; CUFÍ S; VÁZQUEZ-MARTÍN A

mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to stem cell renewal and aging.

CELL CYCLE; Lugar: Austin, Texas; Año: 2011 vol. 3 p. 348 - 362

CUFÍ S; VÁZQUEZ-MARTÍN A; OLIVERAS-FERRARÓS C; MARTÍN-CASTILLO B; VELLÓN L; MENENDEZ JA

Autophagy positively regulates the CD44(+) CD24(-/low) breast cancer stem-like phenotype.

CELL CYCLE; Lugar: Austin, Texas; Año: 2011 vol. 10 p. 3871 - 3885

VELLÓN L; GARCÍA-MARTÍN A

Stem Cells Biobanks for Research

DILEMATA; Año: 2011 p. 1 - 16

MENENDEZ JA; CUFÍ S; OLIVERAS-FERRARÓS C; MARTÍN-CASTILLO B; VELLÓN L; JOVEN J; VAZQUEZ MARTIN A

Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer.

Aging; Año: 2011 vol. 3 p. 1063 - 1077

VELLÓN L; ROYO F; MATHIESSEN R; TORRES-FUENZALIDA J; LLORENTI A; PARADA LA

Functional blockade of alpha(5) beta(1) integrin induces scattering and genomic landscape remodeling of hepatic progenitor cells.

BMC CELL BIOLOGY; Lugar: Londres; Año: 2010 vol. 11 p. 1 - 16

ROYO F; PAZ N; ESPINOSA L; MCQUEEN PG; VELLÓN L; PARADA LA

Spatial link between nucleoli and expression of the Zac1 gene.

CHROMOSOMA; Lugar: Berlin; Año: 2009 vol. 118 p. 711 - 722

COLOMER R; LUPU R; PAPADIMITROPOULOU A; VELLÓN L; VÁZQUEZ-MARTÍN A; BRUNET J; FERNÁNDEZ-GUTIÉRREZ A; SEGURA-CARRETERO A; MENENDEZ JA

Giacomo Castelvetro's salads. Anti-HER2 oncogene nutraceuticals since the 17th century?

CLINICAL & TRANSLATIONAL ONCOLOGY; Lugar: Berlin; Año: 2008 vol. 10 p. 30 - 34

VELLÓN L; MENENDEZ JA; LIU H; LUPU R

Up-regulation of alphavbeta3 integrin expression is a novel molecular response to chemotherapy-induced cell damage in a heregulin-dependent manner.

DIFFERENTIATION; Lugar: Amsterdam; Año: 2007 vol. 75 p. 819 - 830

MENENDEZ JA; PAPADIMITROPOULOU A; VELLÓN L; LUPU R

A genomic explanation connecting "Mediterranean diet", olive oil and cancer: oleic acid, the main monounsaturated fatty acid of olive oil, induces formation of inhibitory "PEA3 transcription factor-PEA3 DNA binding site" complexes at the Her-2/neu (erbB-2

EUROPEAN JOURNAL OF CANCER; Lugar: Amsterdam; Año: 2006 vol. 42 p. 2425 - 2432

MENENDEZ JA; VELLÓN L; LUPU R

DNA topoisomerase IIalpha (TOP2A) inhibitors up-regulate fatty acid synthase gene expression in SK-Br3 breast cancer cells: in vitro evidence for a 'functional amplicon' involving FAS, Her-2/neu and TOP2A genes.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE; Lugar: Atenas; Año: 2006 vol. 18 p. 1081 - 1087

VELLÓN L; MENENDEZ JA; LUPU R

A bidirectional "alpha(v)beta(3) integrin-ERK1/ERK2 MAPK" connection regulates the proliferation of breast cancer cells.

MOLECULAR CARCINOGENESIS.; Lugar: New York; Año: 2006 vol. 45 p. 795 - 804

MENENDEZ JA; VELLÓN L; LUPU R

The antiobesity drug Orlistat induces cytotoxic effects, suppresses Her-2/neu (erbB-2) oncogene overexpression, and synergistically interacts with trastuzumab (Herceptin) in chemoresistant ovarian cancer cells.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER; Lugar: Philadelphia; Año: 2006 vol. 16 p. 219 - 221

MENENDEZ JA; VELLÓN L; LUPU R

Antitumoral actions of the anti-obesity drug orlistat (XenicalTM) in breast cancer cells: blockade of cell cycle progression, promotion of apoptotic cell death and PEA3-mediated transcriptional repression of Her2/neu (erbB-2) oncogene.

ANNALS OF ONCOLOGY; Lugar: Oxford; Año: 2005 vol. 16 p. 1253 - 1267

VELLÓN L; MENENDEZ JA; LUPU R

AlphaVbeta3 integrin regulates heregulin (HRG)-induced cell proliferation and survival in breast cancer.

ONCOGENE; Lugar: Londres; Año: 2005 vol. 24 p. 3759 - 3773

MENENDEZ JA; VELLÓN L; LUPU R

Orlistat: from antiobesity drug to anticancer agent in Her-2/neu (erbB-2)-overexpressing gastrointestinal tumors?

EXPERIMENTAL BIOLOGY AND MEDICINE; Lugar: Maywood; Año: 2005 vol. 230 p. 151 - 154

VELLÓN L; GONZÁLEZ-CID M; NEBEL MDEC; LARRIPA I

Additive apoptotic effect of STI571 with the cytoprotective agent amifostine in K-562 cell line.

CANCER CHEMOTHERAPY AND PHARMACOLOGY; Lugar: Berlin; Año: 2005 vol. 55 p. 602 - 608

MENENDEZ JA; VELLÓN L; OZA BP; LUPU R

Does endogenous fatty acid metabolism allow cancer cells to sense hypoxia and mediate hypoxic vasodilatation? Characterization of a novel molecular connection between fatty acid synthase (FAS) and hypoxia-inducible factor-1alpha (HIF-1alpha)-related expre

JOURNAL OF CELLULAR BIOCHEMISTRY; Lugar: New York; Año: 2005 vol. 94 p. 857 - 863

MENENDEZ JA; VELLÓN L; COLOMER R; LUPU R

Oleic acid, the main monounsaturated fatty acid of olive oil, suppresses Her-2/neu (erbB-2) expression and synergistically enhances the growth inhibitory effects of trastuzumab (Herceptin) in breast cancer cells with Her-2/neu oncogene amplification.

ANNALS OF ONCOLOGY; Lugar: Oxford; Año: 2005 vol. 16 p. 359 - 371

MENENDEZ JA; VELLÓN L; COLOMER R; LUPU R

Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene.

JOURNAL OF THE NATIONAL CANCER INSTITUTE.; Lugar: Oxford; Año: 2005 vol. 97 p. 1611 - 1615

MENENDEZ JA; VELLÓN L; COLOMER R; LUPU R

Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity.

INTERNATIONAL JOURNAL OF CANCER. JOURNAL INTERNATIONAL DU CANCER.; Lugar: New York; Año: 2005 vol. 115 p. 19 - 35

MENENDEZ JA; VELLÓN L; MEHMI I; TENG PK; GRIGGS DW; LUPU R

A novel CYR61-triggered 'CYR61-alphavbeta3 integrin loop' regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ERK2 MAPK signaling pathway.

ONCOGENE; Lugar: Londres; Año: 2005 vol. 24 p. 761 - 779

MENENDEZ JA; VELLÓN L; LUPU R

Targeting fatty acid synthase-driven lipid rafts: a novel strategy to overcome trastuzumab resistance in breast cancer cells.

MEDICAL HYPOTHESES; Lugar: ESCOCIA; Año: 2004 vol. 64 p. 997 - 1001

MENENDEZ JA; VELLÓN L; MEHMI I; OZA BP; ROPERO S; COLOMER R; LUPU R

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2004 vol. 101 p. 10715 - 10720

VELLÓN L; GONZÁLEZ-CID M; KARARA A; NEBEL MDEC; CUELLO MT; LARRIPA I

Enhanced uptake of antisense oligonucleotides using cationic liposomes and the apoptotic effect of idarubicin in K-562 cell line.

LEUKEMIA RESEARCH; Lugar: Amsterdam; Año: 2002 vol. 26 p. 669 - 676

SMOLEWSKI P; RUAN Q; VELLÓN L; DARZYNKIEWICZ Z.

Micronuclei assay by laser scanning cytometry

CYTOMETRY; Año: 2001 vol. 45 p. 19 - 26

LOPES EC; GARCÍA MG; VELLÓN L; ALVAREZ E; HAJOS SE

Correlation Between Decreased Apoptosis and Multidrug Resistance (MDR) in Murine Leukemic T Cell Lines Read More: http://informahealthcare.com/doi/abs/10.3109/10428190109099340

LEUKEMIA AND LYMPHOMA; Lugar: Londres; Año: 2001 vol. 42 p. 775 - 787

VELLÓN L; CUELLO T; GARGALLO P ; LARRIPA I

Antisense oligonucleotides increase the apoptotic effect of idarubicin in K-562 cell line

MEDICINA (BUENOS AIRES); Lugar: Buenos Aires; Año: 1999 vol. 60 p. 143 - 145