GALLO, FACUNDO N.; AGOSTINA B. MARQUEZ; FIDALGO, DANIELA M.; ALEJANDRO, DANA; MARIANO DELLAROLE; GARCÍA, CYBELE C.; MARIELA BOLLINI

Antiviral drug discovery: Pyrimidine entry inhibitors for Zika and dengue viruses

EUROPEAN JOURNAL OF MEDICAL CHEMISTRY; Año: 2024

FABIANI, MATÍAS; CASTRO, ELIANA F.; BATTINI, LEANDRO; ROSAS, ROCÍO A.; GÄRTNER, BENJAMIN; BOLLINI, MARIELA; CAVALLARO, LUCÍA V.

Two thiosemicarbazones derived from 1-indanone as potent non-nucleoside inhibitors of bovine viral diarrhea virus of different genotypes and biotypes

VIROLOGY; Año: 2024 vol. 598

EMILSE S. LEAL; MARÍA JOSÉ PASCUAL; ADLER, NATALIA S.; NICOLAS ARRUPE; FERNANDO MERWAISS; LUCIANA GIORDANO; FIDALGO, DANIELA M.; ALVAREZ, DIEGO E.; BOLLINI, MARIELA

Unveiling tetrahydroquinolines as promising BVDV entry inhibitors: Targeting the envelope protein

Virology; Año: 2024 vol. 590

SACERDOTI, MARIANA; GROSS, LISSY Z F; RILEY, ANDREW M.; ZEHNDER, KARIN; GHODE, ABHIJEET; KLINKE, SEBASTIÁN; ANAND, GANESH SRINIVASAN; PARIS, KRISTINA; WINKEL, ANGELIKA; HERBRAND, AMANDA K.; GODAGE, H YASMIN; COZIER, GYLES E.; SÜß, EVELYN; SCHULZE, JÖRG O; PASTOR-FLORES, DANIEL; BOLLINI, MARIELA; CAPPELLARI, MARÍA VICTORIA; SVERGUN, DMITRI; GRÄWERT, MELISSA A.; ARAMENDIA, PEDRO F.; LEROUX, ALEJANDRO E.; POTTER, BARRY V L; CAMACHO, CARLOS J.; BIONDI, RICARDO M.

Modulation of the substrate specificity of the kinase PDK1 by distinct conformations of the full-length protein

SCIENCE SIGNALING; Año: 2023 vol. 16

MONTEMURRO, MILAGROS; ENDERLE, ANA G.; GUTIERREZ, FABIANA; LIZARRAGA, LEONARDO; ALVAREZ, IRENE; GOICOECHEA, HÉCTOR C.; COLLINS, SEBASTIÁN E.; BOLLINI, MARIELA; CULZONI, MARÍA J.

A novel optimized polyoxometalate-modified silver nanocomposite. Application to the development of antibacterial textiles

Materials Today Communications; Año: 2023 vol. 35

FREY, KATHLEEN M.; BERTOLETTI, NICOLE; CHAN, ALBERT H.; IPPOLITO, JOSEPH A.; BOLLINI, MARIELA; SPASOV, KRASIMIR A.; JORGENSEN, WILLIAM L.; ANDERSON, KAREN S.

Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase

Frontiers in Molecular Biosciences; Año: 2022 vol. 9

UMANSKY, CARLA; MORELLATO, AGUSTÍN E.; RIECKHER, MATTHIAS; SCHEIDEGGER, MARCO A.; MARTINEFSKI, MANUELA R.; FERNÁNDEZ, GABRIELA A.; PAK, OLEG; KOLESNIKOVA, KSENIA; REINGRUBER, HERNÁN; BOLLINI, MARIELA; CROSSAN, GERRY P.; SOMMER, NATASCHA; MONGE, MARÍA EUGENIA; SCHUMACHER, BJÖRN; PONTEL, LUCAS B.

Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity

NATURE COMMUNICATIONS; Año: 2022 vol. 13

ENDERLE, ANA G.; FRANCO-CASTILLO, ISABEL; ATRIÁN-BLASCO, ELENA; MARTÍN-RAPÚN, RAFAEL; LIZARRAGA, LEONARDO; CULZONI, MARÍA J.; BOLLINI, MARIELA; DE LA FUENTE, JESÚS M.; SILVA, FILOMENA; STREB, CARSTEN; MITCHELL, SCOTT G.

Hybrid Antimicrobial Films Containing a Polyoxometalate-Ionic Liquid

ACS Applied Polymer Materials; Lugar: washington DC; Año: 2022 vol. 4 p. 4144 - 4153

BATTINI, LEANDRO; FIDALGO, DANIELA M.; ÁLVAREZ, DIEGO E.; BOLLINI, MARIELA

Discovery of a Potent and Selective Chikungunya Virus Envelope Protein Inhibitor through Computer-Aided Drug Design

ACS Infectious Diseases; Año: 2021

JUAN I. DI FILIPPO; . MARIELA BOLLINI; CAVASOTTO, CLAUDIO N.

A machine learning model to predict drug transfer across the human placenta barrier

Frontiers in chemistry; Año: 2021

SCARDINO, VALERIA; BOLLINI, MARIELA; CAVASOTTO, CLAUDIO N.

Combination of pose and rank consensus in docking-based virtual screening: The best of both worlds

RSC Advances; Año: 2021 vol. 11 p. 35383 - 35391

ENDERLE, ANA G.; BOSSO, MATTEO; GROß, RÜDIGER; HEILAND, MAGDALENA; BOLLINI, MARIELA; CULZONI, MARÍA J.; KIRCHHOFF, FRANK; MÜNCH, JAN; STREB, CARSTEN

Increased in vitro Anti-HIV Activity of Caffeinium-Functionalized Polyoxometalates

CHEMMEDCHEM; Año: 2021

GALLO, FACUNDO N.; ENDERLE, ANA G.; PARDO, LUCAS A.; LEAL, EMILSE S.; BOLLINI, MARIELA

Challenges and perspectives in the discovery of dengue virus entry inhibitors

CURRENT MEDICINAL CHEMISTRY.; Año: 2021 vol. 28

SELEEM, MOHAMED A.; RODRIGUES DE ALMEIDA, NATHALIA; CHHONKER, YASHPAL SINGH; MURRY, DARYL J.; GUTERRES, ZAIRA DA ROSA; BLOCKER, AMANDA M.; KUWABARA, SHIOMI; FISHER, DEREK J.; LEAL, EMILSE S.; MARTINEFSKI, MANUELA R.; BOLLINI, MARIELA; MONGE, MARÍA EUGENIA; OUELLETTE, SCOT P.; CONDA-SHERIDAN, MARTIN

Synthesis and Antichlamydial Activity of Molecules Based on Dysregulators of Cylindrical Proteases

JOURNAL OF MEDICINAL CHEMISTRY; Lugar: Washington; Año: 2020 vol. 63 p. 4370 - 4387

FERNÁNDEZ, GABRIELA A.; CASTRO, ELIANA F.; ROSAS, ROCÍO A.; FIDALGO, DANIELA M.; ADLER, NATALIA S.; BATTINI, LEANDRO; ESPAÑA DE MARCO, MARIA J.; FABIANI, MATIAS; BRUNO, ANA M.; BOLLINI, MARIELA; CAVALLARO, LUCIA V.

Design and Optimization of Quinazoline Derivatives: New Non-nucleoside Inhibitors of Bovine Viral Diarrhea Virus

Frontiers in Chemistry; Año: 2020 vol. 8

LEAL, EMILSE S.; ADLER, NATALIA S.; FERNÁNDEZ, GABRIELA A.; GEBHARD, LEOPOLDO G.; BATTINI, LEANDRO; AUCAR, MARIA G.; VIDELA, MARIELA; MONGE, MARÍA EUGENIA; HERNÁNDEZ DE LOS RÍOS, ALEJANDRO; ACOSTA DÁVILA, JOHN ALEJANDRO; MORELL, MARÍA L.; CORDO, SANDRA M.; GARCÍA, CYBELE C.; GAMARNIK, ANDREA V.; CAVASOTTO, CLAUDIO N.; BOLLINI, MARIELA

De novo design approaches targeting an envelope protein pocket to identify small molecules against dengue virus

EUROPEAN JOURNAL OF MEDICAL CHEMISTRY; Año: 2019 vol. 182

BOLLINI, MARIELA; BRUNO, ANA M.; NIÑO, MARÍA E; CASAL, JUAN J.; SASIAMBARRENA, LEANDRO D.; VALDEZ, DAMIÁN A G; BATTINI, LEANDRO; PUENTE, VANESA R.; LOMBARDO, MARÍA E

Synthesis, 2D-QSAR Studies and Biological Evaluation of Quinazoline Derivatives as Potent Anti-Trypanosoma cruzi Agents

Medicinal chemistry (Shariqah (United Arab Emirates)); Año: 2019 vol. 15 p. 265 - 276

CASTRO, ELIANA F.; CASAL, JUAN J.; DE MARCO, MARÍA J. ESPAÑA; BATTINI, LEANDRO; FABIANI, MATÍAS; FERNÁNDEZ, GABRIELA A.; BRUNO, ANA M.; CAVALLARO, LUCÍA V.; BOLLINI, MARIELA

Identification of potent bovine viral diarrhea virus inhibitors by a structure-based virtual screening approach

BIORGANIC AND MEDICINAL CHEMISTRY LETTERS; Año: 2019 vol. 29 p. 262 - 266

BATTINI, LEANDRO; BOLLINI, MARIELA

Challenges and approaches in the discovery of human immunodeficiency virus type-1 non-nucleoside reverse transcriptase inhibitors

MEDICINAL RESEARCH REVIEWS; Año: 2019

PASCUAL, MARÍA JOSÉ; MERWAISS, FERNANDO; LEAL, EMILSE; QUINTANA, MARÍA EUGENIA; CAPOZZO, ALEJANDRA V.; CAVASOTTO, CLAUDIO N.; BOLLINI, MARIELA; ALVAREZ, DIEGO E.

Structure-based drug design for envelope protein E2 uncovers a new class of bovine viral diarrhea inhibitors that block virus entry

ANTIVIRAL RESEARCH; Año: 2018 vol. 149 p. 179 - 190

BOLLINI, MARIELA; LEAL, EMILSE S.; ADLER, NATALIA S.; AUCAR, MARÍA G.; FERNÁNDEZ, GABRIELA A.; PASCUAL, MARÍA J.; MERWAISS, FERNANDO; ALVAREZ, DIEGO E.; CAVASOTTO, CLAUDIO N.

Discovery of Novel Bovine Viral Diarrhea Inhibitors Using Structure-Based Virtual Screening on the Envelope Protein E2

Frontiers in Chemistry; Año: 2018 vol. 6

LEAL, EMILSE S.; AUCAR, M. GABRIELA; GEBHARD, LEOPOLDO G.; IGLESIAS, NESTOR G.; PASCUAL, MARÍA J.; CASAL, JUAN J.; GAMARNIK, ANDREA V.; CAVASOTTO, CLAUDIO N.; BOLLINI, MARIELA

Discovery of novel dengue virus entry inhibitors via a structure-based approach

BIORGANIC AND MEDICINAL CHEMISTRY LETTERS; Año: 2017

LANTAÑO, BEATRIZ; AGUIRRE, JOSÉ M.; DRAGO, ELEONORA V.; BOLLINI, MARIELA; DE LA FABA, DIEGO J.; MUFATO, JORGE D.

Synthesis of benzylidenecycloalkan-1-ones and 1,5-diketones under Claisen–Schmidt reaction: Influence of the temperature and electronic nature of arylaldehydes

SYNTHETIC COMMUNICATIONS; Año: 2017 vol. 47 p. 2202 - 2214

JUAN JOSE CASAL; MARIELA BOLLINI; MARIA ELISA LOMBARDO; ANA MARIA BRUNO

?Thalidomide analogues: Tumor necrosis factor-alphainhibitors and their evaluation as anti-inflammatory agents.?

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES; Lugar: Amsterdam; Año: 2016

MARIELA BOLLINI; JUAN JOSE CASAL; SILVIA E ASIS; EMILSE S LEAL; ANA MARIA BRUNO

Antimalarial activity of novel Imidazoisoquinolinone derivatives correlates with heme binding affinity

MEDICINAL CHEMISTRY RESEARCH; Año: 2015

FREY, KATHLEEN; PULEO, DAVID; SPASOV, KRASIMIR; BOLLINI, MARIELA; JORGENSEN, WILLIAM; ANDERSON KAREN

Toward the Development of Non-nucleoside Catechol Diether Inhibitors with Improved Activity for HIV Reverse Transcriptase Variants

JOURNAL OF MEDICINAL CHEMISTRY; Lugar: Washington; Año: 2015

FREY, KATHLEEN; PULEO, DAVID; SPASOV, KRASIMIR; BOLLINI, MARIELA; JORGENSEN, WILLIAM; ANDERSON KAREN

Structure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants

JOURNAL OF MEDICINAL CHEMISTRY; Lugar: Washington; Año: 2015

WILLIAM T GRAY; KATHLEEN M. FREY,; SARAH B. LASKEY,; ANDREA C. MISLAK,; KRASIMIR A. SPASOV,; WON-GIL LEE,; MARIELA BOLLINI,; ROBERT F SILICIANO,; WILLIAM L JORGENSEN,; KAREN S. ANDERSON

Potent Inhibitors Active Against HIV Reverse Transcriptase with K101P, A Mutation Conferring Rilpivirine Resistance

acs medicinal chemistry letters; Año: 2015 p. 1 - 6

KATHLEEN M. FREY, WILLIAM T. GRAY, KRASIMIR A. SPASOV, MARIELA BOLLINI, RICARDO GALLARDO-MACIAS2, WILLIAM L. JORGENSEN, KAREN S. ANDERSON

Structure-Based Evaluation of C5 Derivatives in the

CHEMICAL BIOLOGY & DRUG DESIGN; Lugar: Londres; Año: 2014 p. 1 - 9

WON-GIL LEE; KATHLEEN M FREY; RICARDO GALLARDO-MACIAS; KRASIMIR A. SPASOV; MARIELA BOLLINI; KAREN S. ANDERSON; WILLIAM L. JORGENSEN

Picomolar Inhibitors of HIV-1 Reverse Transcriptase: Design and Crystallography of Naphthyl Phenyl Ethers

ACS med chem lett; Año: 2014 vol. 5 p. 1259 - 1262

ANDREA C. MISLAK; KATHLEEN M. FREY; MARIELA BOLLINI; WILLIAM L JORGENSEN; KAREN S ANDERSON

A mechanistic and structural invesitagation of modified derivatives of the diaryltriazine class of NNRTIs targeting HIV-1 reverse transcriptase

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS; Lugar: Amsterdam; Año: 2014

WON-GIL LEE, RICARDO GALLARDO-MACIAS, KATHLEEN M. FREY, KRASIMIR A. SPASOV, MARIELA BOLLINI, KAREN S. ANDERSON , WILLIAM L. JORGENSEN

Picomolar Inhibitors of HIV Reverse Transcriptase Featuring Bicyclic

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY; Lugar: Washington; Año: 2013 p. 16705 - 16713

MARIELA BOLLINI, KATHLEEN M. FREY, JOSÉ A. CISNEROS, KRASIMIR A. SPASOV, KALYAN DAS,

Extension into the entrance channel of HIV-1 reverse

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; Lugar: Amsterdam; Año: 2013 vol. 23 p. 5209 - 5212

MARIELA BOLLINI, RICARDO GALLARDO-MACIAS, KRASIMIR A. SPASOV, JULIAN TIRADO-RIVES, KAREN S. ANDERSON, WILLIAM L. JORGENSEN

Optimization of benzyloxazoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase to enhance Y181C potency

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; Lugar: Amsterdam; Año: 2013 p. 1110 - 1113

FERNANDA M. FRANK, ALEJANDRA B. CICCARELLI, MARIELA BOLLINI, ANA M. BRUNO, ALCIRA BATLLE, MARIA E. LOMBARDO

Trypanocidal Activity of Thioamide-Substituted Imidazoquinolinone: Electrochemical Properties and Biological Effects

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE; Lugar: Oxford; Año: 2013 vol. 2013 p. 1 - 10

MARIELA BOLLINI, JOSÉ A. CISNEROS, KRASIMIR A. SPASOV, KAREN S. ANDERSON, WILLIAM L. JORGENSEN

Optimization of diarylazines as anti-HIV agents with dramatically

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; Lugar: Amsterdam; Año: 2013 vol. 23 p. 5213 - 5216

ANIL R. EKKATI, MARIELA BOLLINI, ROBERT A. DOMAOAL, KRASIMIR A. SPASOV, KAREN S. ANDERSON, WILLIAM L. JORGENSEN

Discovery of dimeric inhibitors by extension into the entrance channel of HIV-1 reverse transcriptase

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; Año: 2012 vol. 22 p. 1565 - 1568

2. KATHLEEN M. FREY, MARIELA BOLLINI, ANDREA C. MISLAK, JOSÉ A. CISNEROS, RICARDO GALLARDO-MACIAS, WILLIAM L. JORGENSEN, AND KAREN S. ANDERSON

Crystal Structures of HIV-1 Reverse Transcriptase with Picomolar Inhibitors Reveal Key Interactions for Drug Design

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY; Lugar: Washington; Año: 2012 p. 19501 - 19503

MARIELA BOLLINI, ROBERT A. DOMAOAL, VINAY V. THAKUR, RICARDO GALLARDO-MACIAS, KRASIMIR A. SPASOV, KAREN S. ANDERSON, WILLIAM L. JORGENSEN

Computationally-Guided Optimization of a Docking Hit to Yield Catechol Diethers as Potent Anti-HIV Agents

JOURNAL OF MEDICINAL CHEMISTRY; Año: 2011 vol. 54 p. 8582 - 8591

WILLIAM L. JORGENSEN, MARIELA BOLLINI, VINAY V. THAKUR, ROBERT A. DOMAOAL, KRASIMIR A. SPASOV, AND KAREN S. ANDERSON

Efficient Discovery of Potent Anti-HIV Agents Targeting the Tyr181Cys Variant of HIV Reverse Transcriptase

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY; Año: 2011 vol. 2011 p. 15686 - 15696

CHERYL S. LEUNG, JACOB G. ZEEVAART, ROBERT A. DOMAOAL, MARIELA BOLLINI, VINAY V. THAKUR, KRASIMIR A. SPASOV, KAREN S. ANDERSON, AND WILLIAM L. JORGENSEN

Eastern extension of azoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase; cyano group alternatives

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; Año: 2010 vol. 20 p. 2485 - 2488

ALEJANDRA GERPE, MARIELA BOLLINI, MERCEDES GONZÁLEZ, HUGO CERECETTO

Convenient Route to Primary (Z)-Allyl Amines and Homologs

SYNTHETIC COMMUNICATIONS; Año: 2009 vol. 39 p. 29 - 47

MARIELA BOLLINI; MARIANGELES GONZÁLEZ; ANA MARÍA BRUNO

Microwave-assisted rapid and efficient synthesis of C-alkyl imidazoisoquinolinone derivatives

TETRAHEDRON LETTERS; Año: 2009 vol. 50 p. 1507 - 1509

MARIELA BOLLINI, JUAN JOSÉ CASAL, DIEGO ALVAREZ, LUCÍA BOIANI, MERCEDES GONZÁLEZ, HUGO CERECETTO, ANA M. BRUNO

New potent imidazoisoquinolinone derivatives as anti-Trypanosoma cruzi agents: Biological evaluation and structure-activity relationships

BIOORGANIC & MEDICINAL CHEMISTRY.; Año: 2009 vol. 17 p. 1437 - 1444

GISELA C. MUSCIA, JUAN P. CARNEVALE, MARIELA BOLLINI, SILVIA E. ASÍS

Microwave-assisted Döbner Síntesis of 2-Phenylquinoline-4 carboxilic Acids and their antiparasitc Activities.

JOURNAL OF HETEROCYCLIC CHEMISTRY; Año: 2008 vol. 45 p. 611 - 614

. MARIELA BOLLINI, JUAN JOSÉ CASAL, ANA MARÍA BRUNO

Design, Synthesis and Antitumor Activity of new bis-aminomethylnaphthalenes.

BIOORGANIC & MEDICINAL CHEMISTRY.; Año: 2008 vol. 16 p. 8003 - 8010

G. C. MUSCIA, M. BOLLINI, A. M. BRUNO, S. E. ASÍS

Evaluation of Antiparasitic, Antituberculosis and Antiangiogenic Activities of 3-Aminoquinolin-2-one Derivatives

Journal of the Chilean Chemical Society; Año: 2006 vol. 51 p. 859 - 863

C. MUSCIA, MARIELA BOLLINI, JUAN P. CARNEVALE, ANA M. BRUNO, SILVIA E. ASÍS

Microwave-assisted Friedländer synthesis of quinolines derivatives as potential antimalarial agents.

TETRAHEDRON LETTERS; Año: 2006 vol. 47 p. 8811 - 8815

. MARIELA BOLLINI, SILVIA E. ASÍS, ANA MARÍA BRUNO

Synthesis of 2,3-dihydroimidazo[1,2-b]isoquinoline-5(1H)-one and derivatives.

SYNTHESIS-STUTTGART; Año: 2006 p. 237 - 242

SILVIA E. ASÍS; ANA M. BRUNO; DIEGO A. DOMINICI; MARIELA BOLLINI, CARLOS H. GAOZZA

Chemical Transformations of 3-Amino-2-quinolones.

JOURNAL OF HETEROCYCLIC CHEMISTRY; Lugar: Londres; Año: 2003 vol. 40 p. 107 - 112

ANA MARÍA BRUNO, MARIELA BOLLINI, CARLOS H. GAOZZA

Química de derivados de benzo[g]quinoxalina generadores de posibles nuevas drogas antineoplásicas

Revista Farmaceutica; Año: 2001 vol. 143 p. 35 - 42