INVESTIGADORES
SASIAIN Maria Del Carmen
artículos
HUGO A VALDEZ; JOSE L MARIN-FRANCO; JUAN P GORGOJO; JIMENA ALVAREZ HAYES; BALBOA LUCIANA; MARCELO FERNANDEZ LAHORE; MARIA C SASIAIN; MARIA EUGENIA RODRIGUEZ
Human macrophage polarization shapes B. pertussis intracellular persistence
JOURNAL OF LEUKOCYTE BIOLOGY; Lugar: Bethesda; Año: 2022 vol. 112 p. 173 - 184
IMPERIALE, B.R.; GARCÍA, A.; MINOTTI, A.; GONZÁLEZ MONTANER, P.; MORACHO, L.; MORCILLO, N.S.; PALMERO, D.J.; SASIAIN, M. DEL CARMEN; DE LA BARRERA, S.
Th22 response induced by Mycobacterium tuberculosis strains is closely related to severity of pulmonary lesions and bacillary load in patients with multi-drug-resistant tuberculosis
CLINICAL AND EXPERIMENTAL IMMUNOLOGY; Año: 2021 vol. 203 p. 267 - 280
DUPONT, MAEVA; SOURIANT, SHANTI; BALBOA, LUCIANA; MANH, THIEN-PHONG VU; PINGRIS, KARINE; ROUSSET, STELLA; COUGOULE, CÉLINE; ROMBOUTS, YOANN; POINCLOUX, RENAUD; NEJI, MYRIAM BEN; ALLERS, CAROLINA; KAUSHAL, DEEPAK; KURODA, MARCELO J.; BENET, SUSANA; MARTINEZ-PICADO, JAVIER; IZQUIERDO-USEROS, NURIA; SASIAIN, MARIA DEL CARMEN; MARIDONNEAU-PARINI, ISABELLE; NEYROLLES, OLIVIER; VÉROLLET, CHRISTEL; LUGO-VILLARINO, GEANNCARLO
Tuberculosis-associated IFN-I induces Siglec-1 on tunneling nanotubes and favors HIV-1 spread in macrophages
eLife; Año: 2020 vol. 9
MELANIE GENOULA; JOSÉ LUIS MARÍN FRANCO; MARIANO MAIO; BELÉN DOLOTOWICZ; MALENA FERREYRA; M. AYELÉN MILILLO; RÈMI MASCARAU; EDUARDO JOSÉ MORAÑA; DOMINGO PALMERO; MARIO MATTEO; FEDERICO FUENTES; BEATRIZ LÓPEZ; PAULA BARRIONUEVO; OLIVIER NEYROLLES; CÈLINE COUGOULE; GEANNCARLO LUGO- VILLARINO; CHRISTEL VÉROLLET; MARÍA DEL CARMEN SASIAIN.; LUCIANA BALBOA
Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but Mycobacterium tuberculosis counteracts this process via HIF-1α activation
PLOS PATHOGENS; Lugar: San Francisco; Año: 2020
MARÍN FRANCO, JOSÉ LUIS; GENOULA, MELANIE ; CORRAL, DAN; DUETTE, GABRIEL; FERREYRA, MALENA; MAIO, MARIANO; DOLOTOWICZ, MARÍA BELÉN; APARICIO-TREJO, OMAR EMILIANO; PATIÑO-MARTÍNEZ, EDUARDO; CHARTON, ALISON; MÉTAIS, ARNAUD; FUENTES, FEDERICO; SOLDAN, VANESSA; MORAÑA, EDUARDO JOSÉ; PALMERO, DOMINGO; OSTROWSKI, MATÍAS; SCHIERLOH, PABLO; SÁNCHEZ-TORRES, CARMEN; HERNÁNDEZ-PANDO, ROGELIO; PEDRAZA-CHAVERRI, JOSÉ; ROMBOUTS, YOANN; HUDRISIER, DENIS; LAYRE, EMILIE; VÉROLLET, CHRISTEL; MARIDONNEAU-PARINI, ISABELLE; NEYROLLES, OLIVIER; SASIAIN, MARÍA DEL CARMEN; LUGO-VILLARINO, GEANNCARLO; BALBOA, LUCIANA
Host-Derived Lipids from Tuberculous Pleurisy Impair Macrophage Microbicidal-Associated Metabolic Activity
Cell Reports; Año: 2020 vol. 33
SOURIANT, SHANTI; BALBOA, LUCIANA; DUPONT, MAEVA; PINGRIS, KARINE; KVIATCOVSKY, DENISE; COUGOULE, CÉLINE; LASTRUCCI, CLAIRE; BAH, AICHA; GASSER, ROMAIN; POINCLOUX, RENAUD; RAYNAUD-MESSINA, BRIGITTE; AL SAATI, TALAL; INWENTARZ, SANDRA; POGGI, SUSANA; MORAÑA, EDUARDO JOSE; GONZÁLEZ-MONTANER, PABLO; CORTI, MARCELO; LAGANE, BERNARD; VERGNE, ISABELLE; ALLERS, CAROLINA; KAUSHAL, DEEPAK; KURODA, MARCELO J.; SASIAIN, MARIA DEL CARMEN; NEYROLLES, OLIVIER; MARIDONNEAU-PARINI, ISABELLE; LUGO-VILLARINO, GEANNCARLO; VÉROLLET, CHRISTEL
Tuberculosis Exacerbates HIV-1 Infection through IL-10/STAT3-Dependent Tunneling Nanotube Formation in Macrophages
cell reports; Lugar: Amsterdam; Año: 2019 vol. 26 p. 3586 - 3599
NOEMI YOKOBORI; JOHANA MONTESERIN; BÁRBARA REARTE; ROXANA PAUL; NORBERTO SÍMBOLI; BEATRIZ LÓPEZ; VIVIANA RITACCO; MARÍA DEL CARMEN SASIAIN.
Survival of an epidemic MDR strain of Mycobacterium tuberculosis and its non-prosperous variant within activated macrophages
Infection, Genetics and Evolution; Lugar: Amsterdam; Año: 2019
YOKOBORI N; LÓPEZ B; MONTESERIN J; PAUL R; VON GROLL A; MARTIN A; MARQUINA-CASTILLO B; PALOMINO JC; HERNÁNDEZ-PANDO R; SASIAIN MDC; RITACCO V
Performance of a highly successful outbreak strain of Mycobacterium tuberculosis in a multifaceted approach to bacterial fitness assessment
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (PRINT); Año: 2018
BÉNARD A; SAKWA I; SCHIERLOH P; ANDRE COLOM; MERCIER I; TAILLEUX L; JOUNEAU L; BOUDINOT P; AL-SAATI T; LANG R; REHWINKEL J; LOXTON AG; KAUFMANN SHE; ANTON-LEBERRE V; O'GARRA A; SASIAIN MDC; GICQUEL B; FILLATREAU S; NEYROLLES O; HUDRISIER D
B Cells Producing Type I IFN Modulate Macrophage Polarization in Tuberculosis
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE; Lugar: New York; Año: 2018
GENOULA M; MARÍN FRANCO JL; DUPONT M; KVIATCOVSKY D; MILILLO A; SCHIERLOH P; MORAÑA EJ; POGGI S; PALMERO D; MATA-ESPINOSA D; GONZÁLEZ-DOMÍNGUEZ E; LEÓN CONTRERAS JC; BARRIONUEVO P; REARTE B; CÓRDOBA MORENO MO; FONTANALS A; CROTTA ASIS A; GAGO G; COUGOULE C; NEYROLLES O; MARIDONNEAU-PARINI I; SÁNCHEZ-TORRES C ; HERNÁNDEZ-PANDO R; VÉROLLET C; LUGO-VILLARINO G; SASIAIN MDC; BALBOA L
Formation of Foamy Macrophages by Tuberculous Pleural Effusions Is Triggered by the Interleukin-10/Signal Transducer and Activator of Transcription 3 Axis through ACAT Upregulation.
Frontiers in Immunology; Lugar: Bethesda; Año: 2018 vol. 9
LUGO-VILLARINO G; TROEGELER A; BALBOA L; LASTRUCCI C; DUVAL C; MERCIER I; BÉNARD A; CAPILLA F; AL SAATI T; POINCLOUX R; KONDOVA I; VERRECK FAW; COUGOULE C; MARIDONNEAU-PARINI I; SASIAIN MDC; NEYROLLES O
The C-Type Lectin Receptor DC-SIGN Has an Anti-Inflammatory Role in Human M(IL-4) Macrophages in Response to Mycobacterium tuberculosis.
Frontiers in Immunology; Lugar: Bethesda; Año: 2018 vol. 9
COLADO, ANA; GENOULA, MELANIE; COUGOULE, CÉLINE; MARÍN FRANCO, JOSÉ L.; ALMEJÚN, MARÍA B.; RISNIK, DENISE; KVIATCOVSKY, DENISE; PODAZA, ENRIQUE; ELÍAS, ESTEBAN E.; FUENTES, FEDERICO; MARIDONNEAU-PARINI, ISABELLE; BEZARES, FERNANDO R.; FERNANDEZ GRECCO, HORACIO; CABREJO, MARÍA; JANCIC, CAROLINA; SASIAIN, MARÍA DEL CARMEN; GIORDANO, MIRTA; GAMBERALE, ROMINA; BALBOA, LUCIANA; BORGE, MERCEDES
Effect of the BTK inhibitor ibrutinib on macrophage- and gamma-delta; T cell-mediated response against Mycobacterium tuberculosis
Blood Cancer Journal; Año: 2018 vol. 8
KVIATCOVSKY, DENISE; RIVADENEYRA, LEONARDO; BALBOA, LUCIANA; YOKOBORI, NOEMÍ; LÓPEZ, BEATRIZ; RITACCO, VIVIANA; SCHATTNER, MIRTA; SASIAIN, MARÍA DEL CARMEN; DE LA BARRERA, SILVIA
Mycobacterium tuberculosis Multidrug-Resistant Strain M Induces Low IL-8 and Inhibits TNF- α Secretion by Bronchial Epithelial Cells Altering Neutrophil Effector Functions
MEDIATORS OF INFLAMMATION; Año: 2017 p. 1 - 13
MARINA GARCIA; AYELEN IGLESIAS; VERONICA I. LANDONI; CARLA BELLOMO; AGOSTINA BRUNO; MARIA TERESA CORDOBA; LUCIANA BALBOA; GABRIELA C. FERNANDEZ,; MARIA DEL CARMEN SASIAIN; VALERIA P. MARTıNEZ; PABLO SCHIELOH
Massive plasmablast response elicited in the acute phase of hantavirus pulmonary syndrome
IMMUNOLOGY; Lugar: Londres; Año: 2017
SABIO Y GARCÍA CA; YOKOBORI N; BASILE JI; BALBOA L; GONZALEZ A; LÓPEZ B; RITACCO V; DE LA BARRERA S; SASIAIN MC
C5aR contributes to the weak Th1 profile induced by an outbreak strain of Mycobacterium tuberculosis.
Tuberculosis (Edinb); Lugar: ESCOCIA; Año: 2017
MARIA MERCEDES BIGI; BEATRIZ LOPEZ; FEDERICO CARLOS BLANCO; MARIA DEL CARMEN SASIAIN; SILVIA DE LA BARRERA; MARCELO A. MARTI; EZEQUIEL JORGE SOSA; DARIO AUGUSTO FERNANDEZ DO PORTO; VIVIANA RITACCO; FABIANA BIGI; MARCELO ABEL SORIA
Single nucleotide polymorphisms may explain the contrasting phenotypes of two variants of a multidrug-resistant Mycobacterium tuberculosis strain
Tuberculosis (Edinb); Lugar: ESCOCIA; Año: 2017
JI BASILE; D KVIATCOVSKY; MM ROMERO; L BALBOA; J MONTESERIN; V RITACCO; B LOPEZ; C SABIO Y GARCIA; A GARCIA,; M VESCOVO; P GONZALEZ MONTANER; D PALMERO; M DEL CARMEN SASIAIN; S DE LA BARRERA
Mycobacterium tuberculosis multi-drug-resistant strain M induces IL-17+ IFNg+ CD4+ T cell expansion through an IL-23 and TGFb- dependent mechanism in patients with MDR-TB tuberculosis
CLINICAL AND EXPERIMENTAL IMMUNOLOGY; Lugar: Londres; Año: 2016
LUCIANA BALBOA; DENISE KVIATCOVSKY; PABLO SCHIELOH; MARINA GARCÍA; SILVIA DE LA BARRERA; MARIA DEL CARMEN SASIAIN
Monocyte-derived dendritic cells early exposed to Mycobacterium tuberculosis induce an enhanced T helper 17 response and transfer mycobacterial antigens
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (PRINT); Año: 2016
LUCIANA BALBOA; JORGE BARRIOS-PAYAN; ERIKA GONZÁLEZ-DOMÍNGUEZ; CLAIRE LASTRUCCI; GEANNCARLO LUGO‑VILLARINO; DULCE MATA‑ESPINOZA; PABLO SCHIERLOH; DENISE KVIATCOVSKY; OLIVIER NEYROLLES; ISABELLE MARIDONNEAU‑PARINI; CARMEN SÁNCHEZ‑TORRES; MARÍA DEL CARMEN SASIAIN; ROGELIO HERNÁNDEZ‑PANDO
Diverging biological roles among human monocyte subsets in the context of tuberculosis infection.
CLINICAL SCIENCE (LONDON, ENGLAND : 1979); Lugar: Londres; Año: 2015 vol. 129 p. 319 - 330
LASTRUCCI C; BÉNARD A; BALBOA L; PINGRIS K; SOURIANT S; POINCLOUX R; AL SAATI T; RASOLOFO V; GONZÁLEZ-MONTANER P; INWENTARZ S; MORAÑA EJ; KONDOVA I; VERRECK F.A.W; SASIAIN M.C.; NEYROLLES O; MARIDONNEAU-PARINI I; LUGO-VILLARINO G; COUGOULE C
Tuberculosis is associated with expansion of a motile, permissive and immunomodulatory CD16+ monocyte population via the IL-10/STAT3 axis
CELL RESEARCH; Año: 2015
P SCHIERLOH; V.LANDONI; L.BALBOA; R.MUSELLA; J.CASTAGNINO ; E.MORAÑA; G.C. DE CASADO; D. PALMERO; MC SASIAIN
Human pleural B cells regulate IFN-γ production by local T and NK cells in Mycobacterium tuberculosis-induced delayed hypersensitivity reaction.
CLINICAL SCIENCE (LONDON, ENGLAND : 1979); Lugar: Londres; Año: 2014 vol. 127 p. 391 - 403
L GEFFNER; JI BASILE; N YOKOBORI; D KVIATCOVSKY ; C SABIO Y GARCIA; V. RITACCO; B LOPEZ; MC SASIAIN; S DE LA BARRERA
Mycobacterium tuberculosis Multidrug Resistant Strain M Induces an Altered Activation of Cytotoxic CD8+ T Cells.
PLOS ONE; Lugar: San Francisco; Año: 2014 vol. 9 p. 1 - 13
P SCHIERLOH; L KLEPP; C VAZQUEZ; R.V ROCHA; F.C BLANCO; L BALBOA; B. LOPEZ; V. RITACCO; F.BIGGI; MC SASIAIN
Differential Expression of Immunogenic Proteins on Virulent Mycobacterium tuberculosis Clinical Isolates
BioMed Research International; Lugar: El Cairo; Año: 2014 vol. 2014 p. 1 - 13
GEFFNER L; BASILE J I.; YOKOBORI N; SABIO Y GARCIA C; MUSELLA R; CASTAGNINO J; SASIAIN MC; DE LA BARRERA S
CD4+CD25highFoxp3+ regulatory T lymphocytes suppress IFN?× and CD107 expression in CD4+ and CD8+ T cells from tuberculous pleural effusions.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY; Lugar: Londres; Año: 2014 vol. 175 p. 235 - 245
M.M ROMERO; J.I.BASILE; B. LOPEZ; V. RITACCO; L. BARRERA; MC SASIAIN; M.ALEMAN
Outbreaks of Mycobacterium tuberculosis MDR strains differentially induce neutrophil respiratory burst involving lipid rafts, p38 MAPK and Syk.
BMC INFECTIOUS DISEASES; Lugar: Londres; Año: 2014 vol. 14 p. 262 - 275
NOEMÍ YOKOBORI; BEATRIZ LÓPEZ; LAURA GEFFNER; CARMEN SABIO Y GARCIA; PABLO SCHIERLOH; LUCIA BARRERA; SILVIA DE LA BARRERA; SHUNSUKE SAKAI; IKUO KAWAMURA; MASO MTSUYAMA; VIVIANA RITACCO; MARIA DEL CARMEN SASIAIN
Two genetically-related multidrug-resistant Mycobacterium tuberculosis strains induce divergent outcomes of infection in two human macrophage models
Infection, Genetics and Evolution; Lugar: Amsterdam; Año: 2013 vol. 16 p. 151 - 156
BALBOA LUCIANA; MARIA MERCEDES ROMERO; EVANGELINA LABORDE; CARMEN SABIO Y GARCIA; JUAN BASILE; PABLO SCHIERLOH; NOEMI YOKOBORI; MUSELLA ROSA; JORGE CASTAGNINO; SILVIA DE LA BARRERA; MARIA DEL CARMEN SASIAIN; MERCEDES ALEMAN
Impaired dendritic cell differentiation of CD16-positive monocytes in tuberculosis: Role of p38 MAPK
EUROPEAN JOURNAL OF IMMUNOLOGY; Lugar: Weinheim; Año: 2013 vol. 43 p. 335 - 347
ROMERO MERCEDES; BALBOA LUCIANA; BASILE, JUAN;; LOPEZ BEATRIZ; RITACCO VIVIANA; DE LA BARRERA SILVIA; SASIAIN MARÍA DEL CARMEN; BARRERA LUCÍA; ALEMÁN MERCEDES
Clinical isolates of Mycobacterium tuberculosis differ in their ability to induce respiratory burst and apoptosis in neutrophils as a possible mechanism of immune escape.
CLINICAL AND DEVELOPMENTAL IMMUNOLOGY; Lugar: New York; Año: 2012 p. 1 - 11
YOKOBORI N, SABIO Y GARCÍA CA, GEFFNER L, SCHIERLOH P, LÓPEZ B, RITACCO V, BARRERA L, DE LA BARRERA S, DEL CARMEN SAISIAIN M.
Differential induction of macrophage cell death by antigens of a clustered and a non-clustered multidrug-resistant Mycobacterium tuberculosis strain from Haarlem family.
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY; Lugar: Londres; Año: 2012 vol. 66 p. 363 - 371
BALBOA LUCIANA; MARÍA MERCEDES ROMERO; JUAN BASILE; SABIO Y GARCÍA, CARMEN;; SCHIERLOH PABLO; YOKOBORI NOEMÍ; GEFFNER LAURA,; MUSELLA ROSA; CASTAGNINO JORGE; ABBATE EDUARDO; DE LA BARRERA SILVIA; SASIAIN MARÍA DEL CARMEN; ALEMÁN MERCEDES
Paradoxical role of CD16+CCR2+CCR5+ monocytes in tuberculosis: efficient APC in pleural effusion but also mark disease severity in blood.
JOURNAL OF LEUKOCYTE BIOLOGY; Lugar: Bethesda; Año: 2011 vol. 90 p. 69 - 75
BASILE, JUAN;; GEFFNER LAURA,; ROMERO MERCEDES; BALBOA LUCIANA; SABIO Y GARCÍA, CARMEN;; RITACCO VIVIANA; GARCÍA ANA; CUFFRÉ MÓNICA; ABATTE E,; LÓPEZ, BEATRIZ;; BARRERA LUCÍA; AMBROGGI M; ALEMÁN MERCEDES; SASIAIN MARÍA DEL CARMEN; DE LA BARRERA SILVIA
Outbreaks of mycobacterium tuberculosis MDR strains induce high IL-17 T-cell response in patients with MDR tuberculosis that is closely associated with high antigen load
JOURNAL OF INFECTIOUS DISEASES; Lugar: Chicago; Año: 2011 vol. 204 p. 1054 - 1064
BALBOA L, ; ROMERO MM, ; YOKOBORI N, ; SCHIERLOH P, ; GEFFNER L, ; BASILE JI, ; MUSELLA RM,; ABBATE E, ; DE LA BARRERA S, ; SASIAIN MC, ; ALEMÁN M
Mycobacterium tuberculosis Impairs Dendritic Cell Response by Altering CD1b, DC-SIGN and MR Profile
IMMUNOLOGY AND CELL BIOLOGY; Año: 2010 vol. 88 p. 716 - 726
BLANCO FC, ; SCHIERLOH P,; BIANCO MV,; CAIMI K,; MEIKLE V,; ALITO AE,; CATALDI AA, ; SASIAIN M DEL C, ; BIGI F
Study of the immunological profile towards Mycobacterium bovis antigens in naturally infected cattle.
MICROBIOLOGY AND IMMUNOLOGY; Año: 2009 vol. 53 p. 460 - 467
YOKOBORI N, ; SCHIERLOH P,; GEFFNER L, ; BALBOA L,; ROMERO M, ; MUSELLA R,; CASTAGNINO J,; DE STEFANO G,; ALEMAN M,; DE LA BARRERA S, ; ABBATE E, ; SASIAIN MC
CD3 expression distinguishes two gamma deltaTCR subsets with different phenotype and effector function in tuberculous pleurisy
CLINICAL AND EXPERIMENTAL IMMUNOLOGY; Año: 2009 vol. 157 p. 385 - 394
SCHIERLOH P, ; YOKOBORI N, ; GEFFNER L, ; BALBOA L, ; ROMERO MM, ; MUSELLA RM, ; ALEMÁN M, ; CASTAGNINO J, ; BASILE J, ; DE LA BARRERA S, ; ABBATE E, ; SASIAIN MC
NK cells from tuberculous pleurisy express high ICAM-1 levels and exert stimulatory effect on local T cells
EUROPEAN JOURNAL OF IMMUNOLOGY; Año: 2009 vol. 39 p. 2450 - 2458
GEFFNER L, ; YOKOBORI N, ; BASILE J, ; SCHIERLOH P, ; BALBOA L, ; ROMERO MM, ; RITACCO V,; VESCOVO M, ; GONZÁLEZ MONTANER P, ; LOPEZ B, ; BARRERA L,; ALEMÁN M, ; ABATTE E, ; SASIAIN MC, ; DE LA BARRERA S
Patients with multidrug resistant tuberculosis display impaired Th1 response and enhanced regulatory T cells levels in response to M and Ra outbreak multidrug resistant Mycobacterium tuberculosis strains
INFECTION AND IMMUNITY; Año: 2009 vol. 77 p. 5025 - 5034
ALEMÁN M; DE LA BARRERA S; SCHIERLOH P; YOKOBORI N; BALDINI M; MUSELLA R; ABBATE E; SASIAIN M C
Spontaneous or Mycobacterium tuberculosis-induced apoptotic neutrophils exert opposite effects on dendritic cell-mediated immune response.
European Journal of Immunology; Año: 2007 vol. 37 p. 1524 - 1537
MARIA VICTORIA RAMOS; GABRIELA C. FERNANDEZ; NATASHA PATEY; PABLO SCHIERLOH; RAMON EXENI,; IRENE GRIMOLDI,; GRACIELA VALLEJO; CHRISTIAN ELÝAS-COSTA; MARIA DEL CARMEN SASIAIN; HOWARD TRACHTMAN; CHRISTOPHE COMBADIERE; FRANCOIS PROULX; MARINA S. PALERMO
Involvement of the fractalkine pathway in the pathogenesis of childhood
Blood; Año: 2007 vol. 109 p. 2438 - 2445
PABLO SCHIERLOH; NOEMI YOKOBORI; MERCEDES ALEMAN; VERONICA LANDONI; LAURA GEFFNER; ROSA M MUSELLA; JORGE CASTAGNINO; MATIAS BALDINI,; EDUARDO ABBATE; SILVIA S. DE LA BARRERA; MARÍA C. SASIAIN.
Mycobacterium tuberculosis-Induced Gamma Interferon Production by Natural Killer Cells Requires Cross Talk with Antigen-Presenting Cells Involving Toll-Like Receptors 2 and 4 and the Mannose Receptor in Tuberculous Pleurisy
INFECTION AND IMMUNITY; Año: 2007 vol. 75 p. 5325 - 5337
FINIASZ MR; FRANCO MC; DE LA BARRERA S,; RUTITZKY L; PIZZARIELLO G; SASIAIN M DEL C; RENAULD JC; VAN SNICK J; FINK S
IL-9 promotes anti-Mycobacterium leprae cytotoxicity: involvement of IFNgamma.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY; Año: 2007 vol. 147 p. 139 - 147
DE LA BARRERA S; ALEMAN M; SASIAIN M.DEL C
Toll-like receptors in human infectious diseases.
CURRENT PHARMACEUTICAL DESIGN; Año: 2006 vol. 12 p. 4173 - 4184
SCHIERLOH, P.; ALEMAN, MERCEDES; YOKOBORI, N.; ALVES, L.; ROLDÁN, N.; ABBATE, EDUARDO; DE LA BARRERA, SILVIA; MARIA DEL CARMEN SASIAIN
NK cell activity in tuberculosis is associated with impaired CD 11 a and ICAM-1 expression: a regulatory role of monocytes in NK activation
Immunology; Lugar: Blackwell Publishing Ltd; Año: 2005 vol. 116 p. 541 - 552
ALEMAN M,; DE LA BARRERA SS; SCHIERLOH PL; ALVES L; YOKOBORI N; BALDINI M,; ABBATE E; SASIAIN MC
In tuberculous pleural effusions, activated neutrophils undergo apoptosis and acquire a dendritic cell-like phenotype.
JOURNAL OF INFECTIOUS DISEASES; Año: 2005 vol. 192 p. 399 - 409
SCHIERLOH PABLO; ALEMAN M; YOKOBORI N,; ALVES L; ROLDAN N; ABBATE E; SASIAIN M DEL C; DE LA BARRERA S
NK cell activity in tuberculosis is associated with impaired CD11a and ICAM-1
IMMUNOLOGY; Año: 2005 vol. 116 p. 541 - 552
SCHIERLOH P.; YOKOBORI N; ALEMAN M; MUSELLA RM; BEIGIER-BOMPADRE M; SAAB MA; ALVES L; ABBATE E; DE LA BARRERA SS; SASIAIN MC
Increased susceptibility to apoptosis of CD56dimCD16+ NK cells induces the enrichment of IFN-gamma-producing CD56bright cells in tuberculous pleurisy.
JOURNAL OF IMMUNOLOGY; Año: 2005 vol. 175 p. 6852 - 6860
DE LA BARRERA, SILVIA; ALEMAN, MERCEDES; MUSELLA, R. M.; SCHIERLOH, P.; PASQUINELLI, V.; GARCÍA, V.; ABBATE, EDUARDO; SASIAIN, MARÍA
IL-10 down-regulates costimulatory molecules on Mycobacterium tuberculosis-pulsed macrophages and impairs the lytic activity of CD4 and CD8-CTL in tuberculosis patients.
Clinical and Experimental Immunology; Año: 2004 vol. 138 p. 128 - 137
ALEMAN, MERCEDES; SCHIERLOH, P.; DE LA BARRERA, SILVIA; MUSELLA, R. M.; SAAB, M.; BALDINI, M.; ABBATE, EDUARDO; SASIAIN, MARÍA
Mycobacterium tuberculosis triggers apoptosis in peripheral neutrophils involving TLR2 AND p38-mitogen protein kinase in tuberculosis patients.
Infection and Immunity; Año: 2004 vol. 72 p. 5150 - 5158
DE LA BARRERA, SILVIA; FINIAISZ, MARTA; FINK, SUSANA; ILARREGUI, JUAN; ALEMAN, MERCEDES; OLIVARES, L.; FRANCO, CLARA; PIZZARIELLO, GRACIELA; SASIAIN, MARÍA
NK cells modulate the cytotoxic activity generated by Mycobacterium leprae-hsp65 in leprosy patients. Role of IL-18 and IL-13.
Clinical and Experimental Immunology; Año: 2004 vol. 135 p. 105 - 113
BEIGIER-BOMPADRE, M.; ALEMAN, MERCEDES; BARRIONUEVO, P.; FRANCO, CLARA; RUBEL, C.; SASIAIN, MARÍA; PALERMO, M.; ABBATE, EDUARDO; ISTURIZ, M.
Monocytes and neutrophils from tuberculosis patients are insensitive to anti-inflammatory effects triggered by the prototypic formyl peptide FMLP
Clinical and Experimental Immunology; Año: 2003 vol. 133 p. 267 - 274
DE LA BARRERA, SILVIA; FINIASZ, MARTA; FRIAS, A.; ALEMAN, MERCEDES; BARRIONUEVO, P.; FINK, SUSANA; FRANCO, CLARA; ABBATE, EDUARDO; SASIAIN, MARÍA
Specific lytic activity against mycobacterial antigens is inversely correlated with the severity of tuberculosis
Clinical and Experimental Immunology; Año: 2003 vol. 132 p. 450 - 461
ALEMAN, MERCEDES; GARCÍA, A.; SAAB, M.; DE LA BARRERA, SILVIA; FINIASZ, MARTA; ABBATE, EDUARDO; SASIAIN, MARÍA
Mycobacterium tuberculosis-induced activation accelerates apoptosis in peripheral blood neutrophils from patients with active tuberculosis.
American Journal Of Respiratory Cell and Molecular Biology; Año: 2002 vol. 27 p. 583 - 592
ALEMAN, MERCEDES; BEIGIER-BOMPADRE, M.; BORGHETTI, CLAUDIA; DE LA BARRERA, SILVIA; ABBATE, EDUARDO; SASIAIN, MARÍA
. Activation of peripheral blood neutrophils from patients with active advanced tuberculosis
Clinical Immunology; Año: 2001 vol. 100 p. 87 - 95
DE LA BARRERA, SILVIA; FINK, SUSANA; FINIASZ, MARTA; ALEMAN, MERCEDES; FARINA, MARÍA; PIZZARIELLO, GRACIELA; SASIAIN, MARÍA
Lysis of autologous macrophages pulsed with hsp10 from Mycobacterium leprae is associated to the absence of bacilli in leprosy
Immunology Letters; Año: 2001 vol. 76 p. 55 - 62
ALEMAN, MERCEDES; DE LA BARRERA, SILVIA; FINK, SUSANA; FINIASZ, MARTA; FARINA, MARÍA; PIZZARIELLO, GRACIELA; SASIAIN, MARÍA
. Interleukin-12 amplifies the M.leprae hsp65-cytotoxic response in the presence of Tumour necrosis factor and Interferon generating CD56 effector cells. Interleukin-4 regulates this effect.
Scandinavian Journal of Immnunology; Año: 2000 vol. 51 p. 262 - 270
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T cell mediated cytotoxicity against mycobacterium antigen-pulsed autologous macrophages in leprosy patients
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