COLQUE, CLAUDIA A.; ALBARRACÍN ORIO, ANDREA G.; TOMATIS, PABLO E.; DOTTA, GINA; MORENO, DIEGO M.; VILA, ALEJANDRO J.; SMANIA, ANDREA M.

Longitudinal Evolution of the Pseudomonas-Derived Cephalosporinase (PDC) Structure and Activity in a Cystic Fibrosis Patient Treated with β-Lactams

mBio; Año: 2022

CAFIERO, JH; MARTINI MC; LOZANO MJ; VACCA C; LAGARES A; TOMATIS PE; DEL PAPA MF

BioF is a novel B2 metallo-β-lactamase from Pseudomonas sp. isolated from an on-farm biopurification system

ENVIRONMENTAL MICROBIOLOGY; Lugar: Londres; Año: 2021

TOMATIS PE; MARCO SCHUETZ; ELINA UMUDUMOV; ANDREAS PLUECKTHUN

Mutations in sigma 70 transcription factor improves expression of functional eukaryotic membrane proteins in Escherichia coli

Scientific Reports; Año: 2019 vol. 9

GONZALEZ MM; ABRIATA LA; TOMATIS PE; VILA AJ

Optimization of Conformational Dynamics in an Epistatic Evolutionary Trajectory

MOLECULAR BIOLOGY AND EVOLUTION; Lugar: Oxford; Año: 2016

MARÍA-ROCÍO MEINI; PABLO E. TOMATIS; DANIEL WEINREICH; ALEJANDRO J. VILA

Quantitative Description of a Protein Fitness Landscape based on Molecular Features

MOLECULAR BIOLOGY AND EVOLUTION; Lugar: Oxford; Año: 2015

JAVIER M. GONZÁLEZ; MARÍA-ROCÍO MEINI; PABLO E. TOMATIS; FRANCISCO J. MEDRANO MARTÍN; JULIA A. CRICCO1; ALEJANDRO J. VILA

Metallo-b-lactamases ensure antibiotic resistance under restrictive zinc concentrations via fine-tuning of metal-ligand interactions

NATURE CHEMICAL BIOLOGY; Año: 2012 p. 698 - 700

ABRIATA LA; SALVERDA MLM; TOMATIS PE

Sequence–function–stability relationships in proteins from datasets functionally annotated variants: The case of TEM b-lactamases

FEBS LETTERS; Lugar: Amsterdam; Año: 2012 p. 3330 - 3335

ABRIATA LA; GONZÁLEZ LJ,; LLARRULL LI; TOMATIS PE; MYERS WK; COSTELLO AL; TIERNEY DL; VILA AJ

Engineered mononuclear variants in Bacillus cereus metallo-beta-lactamase BcII are inactive.

BIOCHEMISTRY; Año: 2008 p. 8590 - 8599

MARCHIARO P; TOMATIS PE; MUSSI MA; PASTERAN F; VIALE AM; LIMANSKY AS; VILA AJ

Biochemical characterization of metallo-beta-lactamase VIM-11 from a Pseudomonas aeruginosa clinical strain.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; Año: 2008 p. 2250 - 2252

PABLO E. TOMATIS; STELLA M. FABIANE; FABIO SIMONA; PAOLO CARLONI; BRIAN J. SUTTON; ALEJANDRO J. VILA

Adaptive protein evolution grants organismal fitness by improving catalysis and flexibility

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2008 vol. 105 p. 20605 - 20610

ANDRES A. POEYLAUT-PALENA; PABLO E. TOMATIS; ANDREAS I. KARSISIOTIS; CHRISTIAN DAMBLON; ERNESTO G. MATA; ALEJANDRO J. VILA

A minimalistic approach to identify substrate binding features in B1 Metallo-b-lactamases

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; Año: 2007

PABLO E. TOMATIS; RODOLFO M. RASIA; LORENZO SEGOVIA; ALEJANDRO J. VILA

Mimicking natural evolution in metallo-b- lactamases through second-shell ligand mutations

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2005 vol. 102 p. 13761 - 13766

LEPEK VC,; D'ANTUONO AL; TOMATIS PE; UGALDE JE; GIAMBIAGI S; UGALDE RA

Analysis of Mesorhizobium loti glycogen operon: effect of phosphoglucomutase (pgm) and glycogen synthase (g/gA) null mutants on nodulation of Lotus tenuis

MOLECULAR PLANT-MICROBE INTERACTIONS; Año: 2002 vol. 15 p. 368 - 375