SILVA, BERENICE ANABEL; LEAL, MARÍA CELESTE; FARIAS, MARÍA ISABEL; NAVA, AGUSTÍN; GALVÁN, DANIELA INÉS; FERNANDEZ, ELMER; PITOSSI, FERNANDO JUAN; FERRARI, CARINA CINTIA

Proteomic analysis reveals candidate molecules to mediate cortical pathology and identify possible biomarkers in an animal model of multiple sclerosis

Frontiers in Immunology; Año: 2025 vol. 16

WENKER, SHIRLEY D.; FARIAS, MARÍA ISABEL; GRADASCHI, VICTORIA; GARCIA, CORINA; BEAUQUIS, JUAN; LEAL, MARÍA CELESTE; FERRARI, CARINA; ZENG, XIANMIN; PITOSSI, FERNANDO J.

Microglia-secreted TNF-α affects differentiation efficiency and viability of pluripotent stem cell-derived human dopaminergic precursors

PLOS ONE; Año: 2023 vol. 18

ERHARDT, BRENDA; FRENKEL, LIA; MARCORA, MARÍA SILVINA; FARÍAS, MARÍA ISABEL; FERRARI, CARINA CINTIA; PITOSSI, FERNANDO JUAN; LEAL, MARÍA CELESTE

Downregulation of Plasma Membrane Ca 2+ ATPase driven by tyrosine hydroxylase-Gal4 reduces Drosophila lifespan independently of effects in neurons

FLY; Año: 2023 vol. 17

SILVA, BERENICE ANABEL; FARÍAS, MARÍA ISABEL; MIGLIETTA, ESTEBAN ALBERTO; LEAL, MARÍA CELESTE; ÁVALOS, JUAN CARLOS; PITOSSI, FERNANDO JUAN; FERRARI, CARINA CINTIA

Understanding the role of the blood brain barrier and peripheral inflammation on behavior and pathology on ongoing confined cortical lesions

Multiple Sclerosis and Related Disorders; Año: 2022 vol. 57

PEREZ MARTIN; ROSSI FABIANA; SABIO GERMAN; BOCICCHIO PABLO ; LEAL MARIA CELESTE; QUESADA-ALLUE LUIS; RABOSSI ALEJANDRO

Drosophila melanogaster mutant for the dopamine recycling pathway shows alterd biological parameters and increased lifespan

ENTOMOLOGIA EXPERIMENTALIS ET APPLICATA; Año: 2021

ERHARDT, BRENDA; MARCORA, MARÍA SILVINA; FRENKEL, LÍA; BOCHICCHIO, PABLO ALEJANDRO; BODIN, DIEGO HERNÁN; SILVA, BERENICE ANABEL; FARÍAS, MARÍA ISABEL; ALLO, MIGUEL ÁNGEL; HÖCHT, CHRISTIAN; FERRARI, CARINA CINTIA; PITOSSI, FERNANDO JUAN; LEAL, MARÍA CELESTE

“Plasma Membrane Calcium ATPase downregulation in dopaminergic neurons alters cellular physiology and motor behavior in Drosophila melanogaster”

EUROPEAN JOURNAL OF NEUROSCIENCE; Año: 2021

SILVA, BERENICE ANABEL; LEAL, MARÍA CELESTE; FARÍAS, MARÍA ISABEL; ERHARDT, BRENDA; GALEANO, PABLO; PITOSSI, FERNANDO JUAN; FERRARI, CARINA CINTIA

Environmental enrichment improves cognitive symptoms and pathological features in a focal model of cortical damage of multiple sclerosis

BRAIN RESEARCH; Año: 2020 vol. 1727

SILVA, BERENICE ANABEL; LEAL, MARÍA CELESTE; FARÍAS, MARÍA ISABEL; AVALOS, JUAN CARLOS; BESADA, CRISTINA HILDA; PITOSSI, FERNANDO JUAN; FERRARI, CARINA CINTIA

A new focal model resembling features of cortical pathology of the progressive forms of multiple sclerosis: Influence of innate immunity

BRAIN BEHAVIOR AND IMMUNITY; Año: 2018 vol. 69 p. 515 - 531

GALEANO, PABLO*AUTORIA COMPARTIDA; LEAL, MARÍA C*AUTORIA COMPARTIDA ; FERRARI, CARINA C.; DALMASSO, MARÍA C.; MARTINO ADAMI, PAMELA V.; FARÍAS, MARÍA I.; CASABONA, JUAN C.; PUNTEL, MARIANA; DO CARMO, SONIA; SMAL, CLARA; ARÁN, MARTÍN; CASTAÑO, EDUARDO M.; PITOSSI, FERNANDO J.; CUELLO, A. CLAUDIO; MORELLI, LAURA

Chronic Hippocampal Expression of Notch Intracellular Domain Induces Vascular Thickening, Reduces Glucose Availability, and Exacerbates Spatial Memory Deficits in a Rat Model of Early Alzheimer

MOLECULAR NEUROBIOLOGY; Lugar: Oregon; Año: 2018

MARTINO ADAMI PV; QUIJANO C; MAGNANI N; GALEANO P; EVELSON P; CASSINA A; DO CARMO S; LEAL MC; CASTAÑO EM; CUELLO AC; MORELLI L

Synaptosomal bioenergetic defects are associated with cognitive impairment in a transgenic rat model of early Alzheimer's disease

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM; Lugar: Londres; Año: 2017

CASTELLETTO, V.; RYUMIN, P.; CRAMER, R.; HAMLEY, I. W.; TAYLOR, M.; ALLSOP, D.; REZA, M.; RUOKOLAINEN, J.; ARNOLD, T.; HERMIDA-MERINO, D.; GARCIA, C. I.; LEAL, M. C.; CASTAÑO, E.

Self-Assembly and Anti-Amyloid Cytotoxicity Activity of Amyloid beta Peptide Derivatives

Scientific Reports; Año: 2017 vol. 7

SHIRLEY WENKER; MARIA CELESTE LEAL; MARIA ISABEL FARIAS; ZENG X ; FERNANDO JUAN PITOSSI

Cell therapy for Parkinson's disease: Functional role of the host immune response on survival and differentiation of dopaminergic neuroblasts

BRAIN RESEARCH; Lugar: Amsterdam; Año: 2016

MARTINEZ VIVOT, ROCIO; COPELLO, G; LEAL, MARIA CELESTE; PIÑERO, G; USACH, V; ROZENSZAJN M; MORELLI L; SETTON-AVRUJ P

DMT1 iron uptake in the PNS: bridging the gap between injury and regeneration

METALLOMICS; Lugar: CAMBRIDGE; Año: 2015

PABLO DANIEL RADICE; PATRICIA MATHIEU; MARIA CELESTE LEAL; MARIA ISABEL FARIAS; CARINA FERRARI; MARIANA PUNTEL; ARIEL CHERNOMORETZ; MARIANO SALIBE; FERNANDO JUAN PITOSSI

Fibulin-2 is a key mediator of the pro-neurogenic effect of TGF-beta1 on adult neural stem cells

MOLECULAR AND CELLULAR NEUROSCIENCES.; Año: 2015

MARÍA C. LEAL; NATALIA MAGNANI; SERGIO VILLORDO; CRISTINA MARINO BUSLJE1; PABLO EVELSON; EDUARDO MIGUEL CASTAÑO; LAURA MORELLI

Transcriptional regulation of Insulin Degrading Enzyme modulates mitochondrial Aβ catabolism and functionality

JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2013

LEAL MARIA CELESTE; JUAN CRUZ CASABONA; MARIANA PUNTEL; FERNANDO PITOSSI

Interleukin-1beta and TNF-alpha: reliable targets for protective therapies in Parkinson ´s Disease?

frontiers in cellular neuroscience; Año: 2013

EDUARDO M. CASTAÑO, CHERA L. MAAROUF, TERENCE WU, MARÍA CELESTE LEAL, CHARISSE M. WHITESIDE, LIH-FEN LUE, TYLER A. KOKJOHN, MARWAN N. SABBAGH, THOMAS G. BEACH AND ALEX E. ROHER

Alzheimer Disease Periventricular White Matter Lesions Exhibit Specific Proteomic Profile Alterations

NEUROCHEMISTRY INTERNATIONAL; Lugar: Amsterdam; Año: 2012

AGATA FERNÁNDEZ-GAMBA, MARÍA CELESTE LEAL, CHERA L. MAAROUF, CHRISTIANE RICHTER-LANDSBERG, TERENCE WU, LAURA MORELLI, ALEX E. ROHER, EDUARDO M. CASTAÑO

Collapsin response mediator protein-2 phosphorylation promotes the reversible retraction of oligodendrocyte processes in response to non-lethal oxidative stress.

JOURNAL OF NEUROCHEMISTRY; Lugar: Londres; Año: 2012 vol. 121 p. 985 - 995

LEAL MC; SURACE EI; HOLGADO MP,; FERRARI CC; TARELLI R, ; ,PITOSSI F; WISNIEWSKI T; CASTAÑO EM; LEAL MC, CASTAÑO EM, MORELLI, L.

Notch signaling proteins HES-1 and Hey-1 bind to insulin degrading enzyme (IDE) proximal promoter and repress its transcription and activity: implications for cellular Abeta metabolism

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH; Lugar: Amsterdam; Año: 2011 vol. 1823 p. 227 - 235

AYELÉN BULLOJ*, MARIA CELESTE LEAL* AUTORIA COMPARTIDA, HUAXI XU, EDUARDO M. CASTAÑO, AND LAURA MORELLI.

INSULIN-DEGRADING ENZYME SORTING IN EXOSOMES: A SECRETORY PATHWAY FOR A KEY BRAIN Abeta-DEGRADING PROTEASE

JOURNAL OF ALZHEIMER'S DISEASE; Año: 2010 vol. 19 p. 79 - 95

FERNANDEZ-GAMBA, A; LEAL, MC; MORELLI, L; CASTAñO, EM

Insulin-degrading enzyme: structure-function relationship and its possible roles in health and disease

CURRENT PHARMACEUTICAL DESIGN.; Año: 2009 vol. 15 p. 3644 - 3655

MARÍA CELESTE LEAL, ÁGATA CLAUDIA FERNÁNDEZ GAMBA, LAURA MORELLI Y EDUARDO MIGUEL CASTAÑO.

Proteólisis cerebral del péptido amiloide β: relevancia de enzima degradadora de insulina en la enfermedad de Alzheimer

MEDICINA (BUENOS AIRES); Año: 2009 vol. 69 p. 466 - 472

AYELÉN BULLOJ, MARÍA CELESTE LEAL, EZEQUIEL IGNACIO SURACE, XUE ZHANG, HUAXI XU, MARÍA DOLORES LEDESMA, EDUARDO MIGUEL CASTAÑO, LAURA MORELLI.

Detergent resistant membrane-associated IDE in brain tissue and cultured cells: Relevance to A?Ò and insulin degradation

MOLECULAR NEURODEGENERATION; Año: 2008 vol. 3 p. 1 - 13

MARIA C. LEAL, VERONICA B. DORFMAN, AGATA C. FERNANDEZ GAMBA, BLAS FRANGIONE, THOMAS WISNIEWSKI, EDUARDO M. CASTAñO, EINAR M. SIGURDSSON, LAURA MORELLI

Plaque-associated over expression of insulin degrading enzyme in the cerebral cortex of aged transgenic Tg2576 mice with Alzheimer pathology.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY; Lugar: Filadelfia; Año: 2006 vol. 65 p. 976 - 986