GANCEDO, S. N.; SAHORES, A.; GÓMEZ, N.; DI SIERVI, N.; MAY, M.; YANEFF, A.; DE SOUSA SERRO, M. G.; FRAUNHOFFER, N.; DUSETTI, N.; IOVANNA, J.; SHAYO, C.; DAVIO, C. A.; GONZÁLEZ, B.

The xenobiotic transporter ABCC4/MRP4 promotes epithelial mesenchymal transition in pancreatic cancer

Frontiers in Pharmacology; Año: 2024 vol. 15

SAHORES, ANA; GONZÁLEZ, ANGELA RODRÍGUEZ; YANEFF, AGUSTÍN; MAY, MARÍA; GÓMEZ, NATALIA; MONCZOR, FEDERICO; FERNÁNDEZ, NATALIA; DAVIO, CARLOS; SHAYO, CARINA

Ceefourin-1, a MRP4/ABCC4 inhibitor, induces apoptosis in AML cells enhanced by histamine

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS; Año: 2023 vol. 1867

BURGHI, VALERIA; ECHEVERRÍA, EMILIANA B.; ZAPPIA, CARLOS D.; DÍAZ NEBREDA, ANTONELA; RIPOLL, SONIA; GÓMEZ, NATALIA; SHAYO, CARINA; DAVIO, CARLOS A.; MONCZOR, FEDERICO; FERNÁNDEZ, NATALIA C.

Biased agonism at histamine H1 receptor: Desensitization, internalization and MAPK activation triggered by antihistamines

EUROPEAN JOURNAL OF PHARMACOLOGY; Año: 2021 vol. 896

FABIAN, LUCAS; TAVERNA PORRO, MARISA; GÓMEZ, NATALIA; SALVATORI, MELINA; TURK, GABRIELA; ESTRIN, DARÍO; MOGLIONI, ALBERTINA

Design, synthesis and biological evaluation of quinoxaline compounds as anti-HIV agents targeting reverse transcriptase enzyme

EUROPEAN JOURNAL OF MEDICAL CHEMISTRY; Lugar: Paris; Año: 2020 vol. 188

RODRÍGUEZ GONZÁLEZ, ANGELA; SAHORES, ANA; DÍAZ?NEBREDA, ANTONELA; YANEFF, AGUSTÍN; DI SIERVI, NICOLÁS; GÓMEZ, NATALIA; MONCZOR, FEDERICO; FERNÁNDEZ, NATALIA; DAVIO, CARLOS; SHAYO, CARINA

MRP4/ABCC4 expression is regulated by histamine in acute myeloid leukemia cells, determining cAMP efflux

FEBS JOURNAL; Año: 2020

COLAVITA, JUAN PABLO MELANA; TODARO, JUAN SANTIAGO; DE SOUSA, MAXIMILIANO; MAY, MARÍA; GÓMEZ, NATALIA; YANEFF, AGUSTIN; DI SIERVI, NICOLAS; AGUIRRE, MARÍA VICTORIA; GUIJAS, CARLOS; FERRINI, LEANDRO; DAVIO, CARLOS; RODRÍGUEZ, JUAN PABLO

Multidrug resistance protein 4 (MRP4/ABCC4) is overexpressed in clear cell renal cell carcinoma (ccRCC) and is essential to regulate cell proliferation

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES; Año: 2020 vol. 161 p. 836 - 847

SAHORES, A.; CAROZZO, A.; MAY, M.; GÓMEZ, N.; DI SIERVI, N.; DE SOUSA SERRO, M.; YANEFF, A.; RODRÍGUEZ-GONZÁLEZ, A.; ABBA, M.; SHAYO, C.; DAVIO, C.

Multidrug transporter MRP4/ABCC4 as a key determinant of pancreatic cancer aggressiveness

Scientific Reports; Año: 2020 vol. 10

GONZÁLEZ, BETINA; BERNARDI, ALEJANDRA; TORRES, OSCAR V.; JAYANTHI, SUBRAMANIAM; GOMEZ, NATALIA; SOSA, MÁXIMO H.; GARCÍA-RILL, EDGAR; URBANO, FRANCISCO J.; CADET, JEAN-LUD; BISAGNO, VERÓNICA

HDAC superfamily promoters acetylation is differentially regulated by modafinil and methamphetamine in the mouse medial prefrontal cortex

ADDICTION BIOLOGY; Año: 2019

GONZÁLEZ, BETINA; TORRES, OSCAR V.; JAYANTHI, SUBRAMANIAM; GOMEZ, NATALIA; SOSA, MÁXIMO H.; BERNARDI, ALEJANDRA; URBANO, FRANCISCO J.; GARCÍA-RILL, EDGAR; CADET, JEAN-LUD; BISAGNO, VERÓNICA

The effects of single-dose injections of modafinil and methamphetamine on epigenetic and functional markers in the mouse medial prefrontal cortex: potential role of dopamine receptors

PROGRESS OF NEUROPSYCHOPHARMACOLOGY AND BIOLOGICAL PSYCHIATRY; Año: 2019 vol. 88 p. 222 - 234

CAROZZO, ALEJANDRO; YANEFF, AGUSTÍN; GÓMEZ, NATALIA; DI SIERVI, NICOLÁS; SAHORES, ANA; DIEZ, FEDERICO; ATTORRESI, ALEJANDRA I.; RODRÍGUEZ-GONZÁLEZ, ÁNGELA; MONCZOR, FEDERICO; FERNÁNDEZ, NATALIA; ABBA, MARTÍN; SHAYO, CARINA; DAVIO, CARLOS

Identification of MRP4/ABCC4 as a target for reducing the proliferation of pancreatic ductal adenocarcinoma cells by modulating the cAMP efflux

MOLECULAR PHARMACOLOGY; Año: 2019 vol. 96 p. 13 - 25

GENTILE, EMILIANO ALBERTO; CASTRONUOVO, CYNTHIA CECILIA; CUESTAS, MARÍA LUJÁN; GÓMEZ, NATALIA; DAVIO, CARLOS; OUBIÑA, JOSÉ RAÚL; MATHET, VERÓNICA LIDIA

F127 poloxamer effect on cytotoxicity induction of tumour cell cultures treated with doxorubicin

JOURNAL OF PHARMACY AND PHARMACOLOGY; Año: 2019

GONZÁLEZ, BETINA; JAYANTHI, SUBRAMANIAM; GOMEZ, NATALIA; TORRES, OSCAR V.; SOSA, MÁXIMO H.; BERNARDI, ALEJANDRA; URBANO, FRANCISCO J.; GARCÍA-RILL, EDGAR; CADET, JEAN-LUD; BISAGNO, VERÓNICA

Repeated methamphetamine and modafinil induce differential cognitive effects and specific histone acetylation and DNA methylation profiles in the mouse medial prefrontal cortex

PROGRESS OF NEUROPSYCHOPHARMACOLOGY AND BIOLOGICAL PSYCHIATRY; Año: 2018 vol. 82 p. 1 - 11

SORDELLI, M; BELTRAME, J; ZOTTA, E; GOMEZ, N; DMYTRENKO, G ; SALES, ME; BLOIS, S; DAVIO, C; PEREZ MARTINEZ, S; FRANCHI, A; RIBEIRO, ML

Endogenous lysophosphatidic acid participates in vascularization and decidualization at the maternal-fetal interface in the rat

REPRODUCTION FERTILITY AND DEVELOPMENT; Lugar: Collingwood; Año: 2017

YANEFF, AGUSTÍN; SAHORES, ANA; GOMEZ, NATALIA; CAROZZO, ALEJANDRO; SHAYO, CARINA; DAVIO, CARLOS

MRP4/ABCC4 as a new therapeutic target: meta-analysis to determine cAMP binding sites as a tool for drug design

CURRENT MEDICINAL CHEMISTRY.; Año: 2017 vol. 25

YANEFF, A; SIGAUT, L; GOMEZ, N; ALIAGA FANDIÑO, C; ALLEVA, K; PIETRASANTA, L I; AMODEO, G

Loop B serine of a plasma membrane aquaporin type PIP2 but not PIP1 plays a key role in pH sensing.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES; Lugar: Amsterdam; Año: 2016

CABRERA M; GOMEZ, N; REMES LENICOV F; ECHEVERRIA, E; SHAYO, C; MOGLIONI, A; FERNANDEZ, N; DAVIO, C

G2/M Cell Cycle Arrest and Tumor Selective Apoptosis of Acute Leukemia Cells by a Promising Benzophenone Thiosemicarbazone Compound.

PLOS ONE; Lugar: San Francisco; Año: 2015

CAROZZO, A; DIEZ, FEDERICO; GOMEZ, N; CABRERA M; SHAYO, C; DAVIO, C; FERNANDEZ, N

Dual role of cAMP in the transcriptional regulation of multidrug resistance-associated protein 4 (MRP4) in pancreatic adenocarcinoma cell lines.

PLOS ONE; Lugar: San Francisco; Año: 2015

DIEGO SANTOS; BEATRIZ PARAJÓN-COSTA; MIRIAM ROSSI; FRANCESCO CARUSO; DIEGO BENÍTEZ; JAVIER VARELA; HUGO CERECETTO; MERCEDES GONZÁLEZ; NATALIA GÓMEZ; MARÍA E. CAPUTTO; ALBERTINA G. MOGLIONI; GRACIELA Y. MOLTRASIO; LILIANA M. FINKIELSZTEIN; DINORAH GAMBINO

Activity on Trypanosoma cruzi, erythrocytes lysis and biologically relevant physicochemical properties of Pd(II) and Pt(II) complexes of thiosemicarbazones derived from 1-indanones.

JOURNAL OF INORGANIC BIOCHEMISTRY; Lugar: Amsterdam; Año: 2012 vol. 117 p. 270 - 276

RAMIRO VAZQUEZ; RIVEIRO, MARÍA EUGENIA; VERMEULEN, MONICA; ALONSO, ELIANA; MONDILLO, CAROLINA; FACORRO, GRACIELA; LIDIA PIEHL; GOMEZ, NATALIA; MOGLIONI, ALBERTINA; FERNANDEZ, NATALIA; BALDI, ALBERTO; SHAYO, CARINA; DAVIO, CARLOS

Structure-anti-leukemic activity relationship study of ortho-dihydroxycoumarins in U-937 cells: Key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action.

BIOORGANIC & MEDICINAL CHEMISTRY.; Lugar: Amsterdam; Año: 2012 p. 5537 - 5549

GOMEZ, NATALIA; SANTOS, DIEGO; VAZQUEZ, RAMIRO; SUESCUN, LEOPOLDO; MOMBRU, ALVARO; VERMEULEN, MONICA; FINKIELSZTEIN, LILIANA; SHAYO, CARINA; MOGLIONI, ALBERTINA; GAMBINO, DINORAH; DAVIO, CARLOS

Synthesis, Structural Characterization and Pro-apoptotic Activity of 1-Indanone thiosemicarbazone Platinum(II) and Palladium(II) Complexes: Potential as Antileukemic Agents

CHEMMEDCHEM; Año: 2011

MARIA E. RIVEIRO; RAMIRO VAZQUEZ; ALBERTINA MOGLIONI; NATALIA GOMEZ; ALBERTO BALDI; CARLOS DAVIO; CARINA SHAYO

Biochemical mechanisms underlying the pro-apoptotic activity of 7,8-dihydroxy-4-methylcoumarin in human leukemic cells

BIOCHEMICAL PHARMACOLOGY; Año: 2008 vol. 75 p. 725 - 736

MARIA E. RIVEIRO; ALBERTINA MOGLIONI; RAMIRO VAZQUEZ; NATALIA GOMEZ; GRACIELA FACORROC; LIDIA PIEHL; EMILIO RUBIN DE CELIS; CARINA SHAYO; CARLOS DAVIO

Structural insights into hydroxycoumarin-induced apoptosis in U-937 cells

BIOORGANIC & MEDICINAL CHEMISTRY.; Año: 2008 vol. 16 p. 2665 - 2675