INVESTIGADORES
RUBINSTEIN Marcelo
artículos
RUBINSTEIN, MARCELO
Dopaminergic innervation at the central nucleus of the amygdala reveals distinct topographically segregated regions
Brain Structure and Function; Año: 2023 vol. 228 p. 663 - 675
RUBINSTEIN, MARCELO
Accelerated Evolution Analysis Uncovers PKNOX2 as a Key Transcription Factor in the Mammalian Cochlea
MOLECULAR BIOLOGY AND EVOLUTION; Año: 2023 vol. 40
CASEY, ERIC; AVALE, MARÍA ELENA; KRAVITZ, ALEXXAI; RUBINSTEIN, MARCELO
Partial Ablation of Postsynaptic Dopamine D2 Receptors in the Central Nucleus of the Amygdala Increases Risk Avoidance in Exploratory Tasks
ENEURO; Año: 2022 vol. 9
LEE, GLORIA S.; GRAHAM, DEVON L.; NOBLE, BRENDA L.; TRAMMELL, TAYLOR S.; MCCARTHY, DEIRDRE M.; ANDERSON, LISA R.; RUBINSTEIN, MARCELO; BHIDE, PRADEEP G.; STANWOOD, GREGG D.
Behavioral and Neuroanatomical Consequences of Cell-Type Specific Loss of Dopamine D2 Receptors in the Mouse Cerebral Cortex
Frontiers in Behavioral Neuroscience; Año: 2022 vol. 15
YU, HUI; RUBINSTEIN, MARCELO; LOW, MALCOLM J.
Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes
eLife; Año: 2022 vol. 11
CUTANDO, LAURA; PUIGHERMANAL, EMMA; CASTELL, LAIA; TAROT, PAULINE; BELLE, MORGANE; BERTASO, FEDERICA; ARANGO-LIEVANO, MARGARITA; ANGO, FABRICE; RUBINSTEIN, MARCELO; QUINTANA, ALBERT; CHÉDOTAL, ALAIN; MAMELI, MANUEL; VALJENT, EMMANUEL
Cerebellar dopamine D2 receptors regulate social behaviors
NATURE NEUROSCIENCE.; Año: 2022 vol. 25 p. 900 - 911
RUBINSTEIN, MARCELO
Dopamine D2Rs coordinate cue-evoked changes in striatal acetylcholine levels
eLife; Año: 2022 vol. 11
RUBINSTEIN, MARCELO
Functional and pharmacological role of the dopamine D4 receptor and its polymorphic variants
Frontiers in Endocrinology; Año: 2022 vol. 13
COLABIANCHI, AITANA M. CASTRO; TAVELLA, MARIÁ B.; LÓPEZ, LAURA E. BOYADJIÁN; RUBINSTEIN, MARCELO; FRANCHINI, LUCIÁ F.; LÓPEZ, SILVIA L.
Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage
Biology Open; Año: 2021 vol. 10
CASADÓ-ANGUERA, VERÒNICA; MORENO, ESTEFANÍA; SÁNCHEZ-SOTO, MARTA; CAI, NING SHENG; BONAVENTURA, JORDI; HOMAR-RUANO, PATRICIA; RUBINSTEIN, MARCELO; CORTÉS, ANTONI; CANELA, ENRIC I.; FERRÉ, SERGI; CASADÓ, VICENT
Heteromerization between α2A adrenoceptors and different polymorphic variants of the dopamine D4 receptor determines pharmacological and functional differences. Implications for impulsive-control disorders
PHARMACOLOGICAL RESEARCH; Año: 2021 vol. 170
CURCI, L.; BRUKMAN, N.G.; WEIGEL MUÑOZ, M.; ROJO, D.; CARVAJAL, G.; SULZYK, V.; GONZALEZ, S.N.; RUBINSTEIN, M.; DA ROS, V.G.; CUASNICÚ, P.S.
Functional redundancy and compensation: Deletion of multiple murine Crisp genes reveals their essential role for male fertility
FASEB JOURNAL; Año: 2020 vol. 34 p. 15718 - 15733
LEBLANC, KIMBERLY H.; LONDON, TANISHA D.; SZCZOT, ILONA; BOCARSLY, MIRIAM E.; FRIEND, DANIELLE M.; NGUYEN, KATRINA P.; MENGESHA, MARDA M.; RUBINSTEIN, MARCELO; ALVAREZ, VERONICA A.; KRAVITZ, ALEXXAI V.
Striatopallidal neurons control avoidance behavior in exploratory tasks
MOLECULAR PSYCHIATRY; Año: 2020 p. 1 - 15
TROTTA, MILAGROS; BELLO, ESTEFANÍA PILAR; ALSINA, RAMIRO; TAVELLA, MARÍA BELÉN; FERRÁN, JOSÉ LUIS; RUBINSTEIN, MARCELO; BUMASCHNY, VIVIANA FLORENCIA
Hypothalamic Pomc expression restricted to GABAergic neurons suppresses Npy overexpression and restores food intake in obese mice
Molecular Metabolism; Año: 2020 vol. 37
PUIGHERMANAL, EMMA; CASTELL, LAIA; ESTEVE-CODINA, ANNA; MELSER, SU; KAGANOVSKY, KONSTANTIN; ZUSSY, CHARLEINE; BOUBAKER-VITRE, JIHANE; GUT, MARTA; RIALLE, STEPHANIE; KELLENDONK, CHRISTOPH; SANZ, ELISENDA; QUINTANA, ALBERT; MARSICANO, GIOVANNI; MARTIN, MIQUEL; RUBINSTEIN, MARCELO; GIRAULT, JEAN-ANTOINE; DING, JUN B.; VALJENT, EMMANUEL
Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum
NATURE COMMUNICATIONS; Año: 2020 vol. 11
YU, HUI; THOMPSON, ZOE; KIRAN, SYLEE; JONES, GRAHAM L; MUNDADA, LAKSHMI; RUBINSTEIN, MARCELO; LOW, MALCOLM J
Expression of a hypomorphic Pomc allele alters leptin dynamics during late pregnancy
JOURNAL OF ENDOCRINOLOGY; Año: 2020 vol. 245 p. 115 - 127
HAEL, CLARA E.; ROJO, DANIELA; ORQUERA, DANIELA P.; LOW, MALCOLM J.; RUBINSTEIN, MARCELO
The transcriptional regulator PRDM12 is critical for Pomc expression in the mouse hypothalamus and controlling food intake, adiposity, and body weight
Molecular Metabolism; Año: 2020 vol. 34 p. 43 - 53
ROJO, DANIELA; MCCARTHY, CLARA; RAINGO, JESICA; RUBINSTEIN, MARCELO
Mouse models for V103I and I251L gain of function variants of the human MC4R display decreased adiposity but are not protected against a hypercaloric diet
Molecular Metabolism; Año: 2020 vol. 42
ORQUERA, DANIELA P.; TAVELLA, M. BELÉLN; DE SOUZA, FLAVIO S.J.; NASIF, SOFÍA; LOW, MALCOLM J.; RUBINSTEIN, MARCELO
The homeodomain transcription factor NKX2.1 is essential for the early specification of melanocortin neuron identity and activates Pomc expression in the developing hypothalamus
JOURNAL OF NEUROSCIENCE; Año: 2019 vol. 39 p. 4023 - 4035
BOCARSLY, MIRIAM E.; DA SILVA E SILVA, DANIEL; KOLB, VANESSA; LUDERMAN, KATHRYN D.; SHASHIKIRAN, SANNIDHI; RUBINSTEIN, MARCELO; SIBLEY, DAVID R.; DOBBS, LAUREN K.; ALVAREZ, VERONICA A.
A Mechanism Linking Two Known Vulnerability Factors for Alcohol Abuse: Heightened Alcohol Stimulation and Low Striatal Dopamine D2 Receptors
Cell Reports; Año: 2019 vol. 29 p. 1147 - 1163
CROMBERG, LUCAS E.; SAEZ, TRINIDAD M. M.; OTERO, MARÍA G.; TOMASELLA, EUGENIA; ALLOATTI, MATÍAS; DAMIANICH, ANA; POZO DEVOTO, VICTORIO; FERRARIO, JUAN; GELMAN, DIEGO; RUBINSTEIN, MARCELO; FALZONE, TOMÁS L.
Neuronal KIF5b deletion induces striatum-dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors
JOURNAL OF NEUROCHEMISTRY; Año: 2019 vol. 149 p. 362 - 380
PISCIOTTANO, FRANCISCO; CINALLI, ALEJANDRO R.; STOPIELLO, JUAN MATÍAS; CASTAGNA, VALERIA C.; ELGOYHEN, ANA BELÉN; RUBINSTEIN, MARCELO; GÓMEZ-CASATI, MARÍA EUGENIA; FRANCHINI, LUCÍA F.
Inner Ear Genes Underwent Positive Selection and Adaptation in the Mammalian Lineage
MOLECULAR BIOLOGY AND EVOLUTION; Año: 2019 vol. 36 p. 1653 - 1670
ZHOU, YAN; RUBINSTEIN, MARCELO; LOW, MALCOLM J.; KREEK, MARY JEANNE
V1b Receptor Antagonist SSR149415 and Naltrexone Synergistically Decrease Excessive Alcohol Drinking in Male and Female Mice
ALCOHOLISM: CLINICAL AND EXPERIMENTAL RESEARCH; Año: 2018 vol. 42 p. 195 - 205
STEYN, FREDERIK J.; NGO, SHYUAN T.; CHEN, VICKY PING; BAILEY-DOWNS, LORA C.; XIE, TERESA Y.; GHADAMI, MARTIN; BRIMIJOIN, STEPHEN; FREEMAN, WILLARD M.; RUBINSTEIN, MARCELO; LOW, MALCOLM J.; STOUT, MICHAEL B.
17α-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior
AGING CELL; Año: 2018 vol. 17
FRIEND, DANIELLE M.; DEVARAKONDA, KAVYA; O'NEAL, TIMOTHY J.; SKIRZEWSKI, MIGUEL; PAPAZOGLOU, IOANNIS; KAPLAN, ALANNA R.; LIOW, JEIH-SAN; GUO, JUEN; RANE, SUSHIL G.; RUBINSTEIN, MARCELO; ALVAREZ, VERONICA A.; HALL, KEVIN D.; KRAVITZ, ALEXXAI V.
Basal Ganglia Dysfunction Contributes to Physical Inactivity in Obesity
CELL METABOLISM; Año: 2017 vol. 25 p. 312 - 321
BELLO, E.P.; CASAS-CORDERO, R.; GALIÑANES, G.L.; CASEY, E.; BELLUSCIO, M.A.; RODRÍGUEZ, V.; NOAÍN, D.; MURER, M.G.; RUBINSTEIN, M.
Inducible ablation of dopamine D2 receptors in adult mice impairs locomotion, motor skill learning and leads to severe parkinsonism
MOLECULAR PSYCHIATRY; Año: 2017 vol. 22 p. 595 - 604
RUBINSTEIN, MARCELO; LOW, MALCOLM J.
Molecular and functional genetics of the proopiomelanocortin gene, food intake regulation and obesity
FEBS LETTERS; Año: 2017 vol. 591 p. 2593 - 2606
BONAVENTURA, JORDI; QUIROZ, CÉSAR; CAI, NING-SHENG; RUBINSTEIN, MARCELO; TANDA, GIANLUIGI; FERRÉ, SERGI
Key role of the dopamine D 4 receptor in the modulation of corticostriatal glutamatergic neurotransmission
Science Advances; Año: 2017 vol. 3
BURKE, LUKE K.; OGUNNOWO-BADA, EMMANUEL; GEORGESCU, TEODORA; CRISTIANO, CLAUDIA; DE MORENTIN, PABLO B. MARTINEZ; VALENCIA TORRES, LOURDES; D'AGOSTINO, GIUSEPPE; RICHES, CHRISTINE; HEELEY, NICHOLAS; RUAN, YUE; RUBINSTEIN, MARCELO; LOW, MALCOLM J.; MYERS, MARTIN G.; ROCHFORD, JUSTIN J.; EVANS, MARK L.; HEISLER, LORA K.
Lorcaserin improves glycemic control via a melanocortin neurocircuit
Molecular Metabolism; Año: 2017 vol. 6 p. 1092 - 1102
ZHOU, Y.; RUBINSTEIN, M.; LOW, M. J.; KREEK, M. J.
Hypothalamic-specific proopiomelanocortin deficiency reduces alcohol drinking in male and female mice
GENES BRAIN AND BEHAVIOR; Año: 2017 vol. 16 p. 449 - 461
KAVALJIT H. CHHABRA, JESSICA M. ADAMS,1,2 BRIAN FAGEL,1 DANIEL D. LAM,1 NATHAN QI, MARCELO RUBINSTEIN AND MALCOLM J. LOW
Hypothalamic POMC Deficiency Improves Glucose Tolerance Despite Insulin Resistance by Increasing Glycosuria.
DIABETES; Año: 2016 vol. 65 p. 660 - 672
LUQUE, GUILLERMINA MARÍA; LOPEZ-VICCHI, FELICITAS; MARÍA ORNSTEIN, ANA; BRIE, BELÉN; DE WINNE, CATALINA; FIORE, ESTEBAN; PEREZ-MILLAN, MARIA INÉS; MAZZOLINI, GUILLERMO; RUBINSTEIN, MARCELO; BECU-VILLALOBOS, DAMASIA
Chronic hyperprolactinemia evoked by disruption of lactotrope dopamine d2 receptors impacts on liver and adipocyte genes related to glucose and insulin balance
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM; Año: 2016 vol. 311 p. 974 - 988
CHHABRA, KAVALJIT H.; ADAMS, JESSICA M.; JONES, GRAHAM L.; YAMASHITA, MIHO; SCHLAPSCHY, MARTIN; SKERRA, ARNE; RUBINSTEIN, MARCELO; LOW, MALCOLM J.
Reprogramming the body weight set point by a reciprocal interaction of hypothalamic leptin sensitivity and Pomc gene expression reverts extreme obesity
Molecular Metabolism; Año: 2016 vol. 5 p. 869 - 881
LEMOS, JULIA C.; FRIEND, DANIELLE M.; KAPLAN, ALANNA R.; SHIN, JUNG HOON; RUBINSTEIN, MARCELO; KRAVITZ, ALEXXAI V.; ALVAREZ, VERONICA A.
Enhanced GABA Transmission Drives Bradykinesia Following Loss of Dopamine D2 Receptor Signaling
NEURON; Año: 2016 vol. 90 p. 824 - 838
BURKE, LUKE K.; DOSLIKOVA, BARBORA; D'AGOSTINO, GIUSEPPE; GREENWALD-YARNELL, MEGAN; GEORGESCU, TEODORA; CHIANESE, RAFFAELLA; MARTINEZ DE MORENTIN, PABLO B.; OGUNNOWO-BADA, EMMANUEL; CANSELL, CELINE; VALENCIA-TORRES, LOURDES; GARFIELD, ALASTAIR S.; APERGIS-SCHOUTE, JOHN; LAM, DANIEL D.; SPEAKMAN, JOHN R.; RUBINSTEIN, MARCELO; LOW, MALCOLM J.; ROCHFORD, JUSTIN J.; MYERS, MARTIN G.; EVANS, MARK L.; HEISLER, LORA K.
Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons
Molecular Metabolism; Año: 2016 vol. 5 p. 245 - 252
DOBBS, LAUREN K.; KAPLAN, ALANNA R.; LEMOS, JULIA C.; MATSUI, AYA; RUBINSTEIN, MARCELO; ALVAREZ, VERONICA A.
Dopamine Regulation of Lateral Inhibition between Striatal Neurons Gates the Stimulant Actions of Cocaine
NEURON; Año: 2016 vol. 90 p. 1100 - 1113
ORQUERA, DANIELA P.; NASIF, SOFIA; LOW, MALCOLM J.; RUBINSTEIN, MARCELO; DE SOUZA, FLÁVIO S.J.
Essential function of the transcription factor Rax in the early patterning of the mammalian hypothalamus
DEVELOPMENTAL BIOLOGY; Año: 2016 vol. 416 p. 212 - 224
LAM DD, ATTARD CA, MERCER AJ, MYERS JR. MG, RUBINSTEIN M, LOW MJ
Conditional expression of Pomc in the Lepr-positive subpopulation of POMC neurons is sufficient for normal energy homeostasis and metabolism.
ENDOCRINOLOGY; Año: 2015 vol. 156 p. 1292 - 1302
NASIF S, DE SOUZA FJS, GONZÁLEZ LE, YAMASHITA M, ORQUERA DP, LOW MJ, RUBINSTEIN M
Islet-1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2015 vol. 112 p. 1861 - 1870
LAM DD, DE SOUZA FS, NASIF S, YAMASHITA M, LÓPEZ-LEAL R, OTERO-CORCHON V, MEECE K, SAMPATH H, MERCER AJ, WARDLAW SL, RUBINSTEIN M, LOW MJ.
Partially Redundant Enhancers Cooperatively Maintain Mammalian Pomc Expression Above a Critical Functional Threshold
PLOS GENETICS; Lugar: San Francisco; Año: 2015 vol. 11
ROCCHETTI J, ISINGRINI E, DAL BO G, SAGHEBY S, MENEGAUX A, TRONCHE F, LEVESQUE D, MOQUIN L, GRATTON A, WONG TP, RUBINSTEIN M, GIROS B.
Presynaptic D2 Dopamine Receptors Control Long-Term Depression Expression and Memory Processes in the Temporal Hippocampus
BIOLOGICAL PSYCHIATRY; Lugar: Amsterdam; Año: 2015 vol. 77 p. 513 - 525
MARIA CECILIA RAMIREZ, ANA MARIA ORNSTEIN, GUILLERMINA MARIA LUQUE, MARIA INES PEREZ MILLAN, ISABEL GARCIA-TORNADU, MARCELO RUBINSTEIN, AND DAMASIA BECU-VILLALOBOS
Pituitary and Brain Dopamine D2 Receptors Regulate Liver Gene Sexual Dimorphism
ENDOCRINOLOGY; Año: 2015 vol. 156 p. 1040 - 1051
HOLROYD KB, ADROVER MF, FUINO RL, BOCK R, KAPLAN AR, GREMEL CM, RUBINSTEIN M, ALVAREZ VA
Loss of feedback inhibition via D2 autoreceptors enhances acquisition of cocaine taking and reactivity to drug-paired cues.
NEUROPSYCHOPHARMACOLOGY; Lugar: Londres; Año: 2015 vol. 40 p. 1495 - 1509
BURKE LK, DOSLIKOVA B, D'AGOSTINO G, GARFIELD AS, FAROOQ G, BURDAKOV D, LOW M, RUBINSTEIN M, EVANS ML, BILLUPS B, HEISLER LK
5-HT obesity medication efficacy via POMC activation is maintained during aging.
ENDOCRINOLOGY; Año: 2014 vol. 155 p. 3732 - 3738
PEREZ MILLAN MI*, LUQUE GM*, RAMIREZ MC, NOAIN D, ORNSTEIN AM, RUBINSTEIN MARCELO*, BECU-VILLALOBOS D*
Selective disruption of dopamine D2 receptors in pituitary lactotropes increases body weight and adiposity in female mice.
ENDOCRINOLOGY; Año: 2014 vol. 55 p. 829 - 839
GRADY D, THANOS P, CORRADA M, BARNETT JR. J, CIOBANU V, SHUSTAROVICH D, NAPOLI A, GRANDY D, MOYZIS A, RUBINSTEIN M, WANG G-J, KAWAS C, CHEN C, DONG Q, WANG E, VOLKOW N, MOYZIS R
DRD4 genotype predicts longevity in mouse and human.
JOURNAL OF NEUROSCIENCE; Lugar: Washington; Año: 2013 vol. 33 p. 286 - 291
NOAÍN D, PÉREZ-MILLÁN MI, BELLO EP, LUQUE GM, CASAS CORDERO R, GELMAN DM, PEPER M, GARCÍA TORNADU I, LOW MJ, BECU-VILLALOBOS D, RUBINSTEIN M
Central dopamine D2 receptors regulate growth hormone-dependent body growth and pheromone signaling to conspecific males.
JOURNAL OF NEUROSCIENCE; Lugar: Washington; Año: 2013 vol. 33 p. 5834 - 5842
TEITZ T, INOUE M, VALENTINE MB, ZHU K, REHG JE, ZHAO W, FINKELSTEIN D, WANG Y-D, JOHNSON MD, CALABRESE C, RUBINSTEIN M, HAKEM R, WEISS WA, LAHTI JM
Th-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis
CANCER RESEARCH; Lugar: Philadelphia; Año: 2013 vol. 73 p. 4086 - 4097
DE SOUZA FSJ, FRANCHINI LF, RUBINSTEIN M
Exaptation of transposable elements into novel cis-regulatory elements: is the evidence always strong?
MOLECULAR BIOLOGY AND EVOLUTION; Lugar: Oxford; Año: 2013 vol. 30 p. 1239 - 1251
RUBINSTEIN M, DESOUZA FJ
Enhancer evolution and animal diversity
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES; Lugar: Londres; Año: 2013 vol. 368 p. 1 - 12
DOMENÉ S, BUMASCHNY VF, DE SOUZA FSJ, FRANCHINI LF, NASIF S, LOW MJ, RUBINSTEIN M
Enhancer turnover and conserved regulatory function in vertebrate evolution.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES; Lugar: Londres; Año: 2013 vol. 368 p. 1 - 14
GONZÁLEZ S, RANGEL-BARAJAS C, PEPER M, LORENZO R, MORENO E, CIRUELA F, BORYCZ J, ORTIZ J, LLUÍS C, FRANCO R, MCCORMICK PJ, VOLKOW ND, RUBINSTEIN M, FLORAN B, FERRÉ S
Dopamine D(4) receptor, but not the ADHD-associated D(4.7) variant, forms functional heteromers with the dopamine D(2S) receptor in the brain.
MOLECULAR PSYCHIATRY; Lugar: Londres; Año: 2012 vol. 17 p. 650 - 662
FRANCHINI LF, DE SOUZA FJS, LOW MJ, RUBINSTEIN M
Positive selection of co-opted mobile genetic elements in a mammalian gene: if you can?t beat them, join them.
Mobile Genetic Elements; Año: 2012 vol. 2 p. 106 - 109
BUMASCHNY VF, YAMASHITA M, CASAS-CORDERO R, OTERO-CORCHON V, DE SOUZA FJ, RUBINSTEIN M*, LOW MJ*
Obesity programmed mice are rescued by early genetic intervention.
JOURNAL OF CLINICAL INVESTIGATION; Lugar: Ann Arbor, Michigan; Año: 2012 vol. 122 p. 4203 - 4212
LEE AK, SMART JL, RUBINSTEIN M, LOW MJ, TSE A.
Reciprocal regulation of TREK-1 channels by arachidonic acid and CRH in mouse corticotropes.
ENDOCRINOLOGY; Año: 2011 vol. 152 p. 1901 - 1910
DE SOUZA FS, NASIF S, LÓPEZ-LEAL R, LEVI DH, LOW MJ, RUBINSTEIN M.
The estrogen receptor alpha; colocalizes with proopiomelanocortin in hypothalamic neurons and binds to a conserved motif present in the neuron-specific enhancer nPE2.
EUROPEAN JOURNAL OF PHARMACOLOGY; Lugar: Amsterdam; Año: 2011 vol. 660 p. 181 - 187
RUBINSTEIN M, LOW MJ
The smoking gun in nicotine-induced anorexia.
CELL METABOLISM; Lugar: United States; Año: 2011 vol. 14 p. 145 - 147
BELLO EP, MATEO Y, GELMAN DM, NOAÍN D, SHIN JH, LOW MJ, ALVAREZ VA, LOVINGER DM, RUBINSTEIN M
Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors.
NATURE NEUROSCIENCE.; Lugar: Londres; Año: 2011 vol. 14 p. 1033 - 1038
FRANCHINI LF, L¨®PEZ-LEAL R, NASIF S, BEATI P, GELMAN DM, LOW MJ, DE SOUZA FJ, RUBINSTEIN M
Convergent evolution of two mammalian neuronal enhancers by sequential exaptation of unrelated retroposons.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2011 vol. 108 p. 15270 - 15275
GARCÍA-TORNADÚ I; ORSTEIN, A.M.; CHAMSON-REIG, A.; WHEELER, M.B. ; HILL, D.J.; ARANY E; RUBINSTEIN M; BECU-VILLALOBOS D
Disruption of the Dopamine D2 Receptor Impairs Insulin Secretion and Causes Glucose Intolerance
ENDOCRINOLOGY; Año: 2010 p. 1441 - 1450
GARCÍA-TORNADÚ I; RISSO, G.; PEREZ-MILLÁN, M.I.; NOAIN D; DIAZ-TORGA, G; LOW MJ; RUBINSTEIN M; BECU-VILLALOBOS D
Neurotransmitter modulation of the GHRH-GH axis.
Frontiers of Hormone Reseach; Año: 2010 vol. 38 p. 59 - 69
MICHAELIDES M; PAASCAU J; GISPERT JD; FONTEINI D; GRANDY DK; WANG GJ; DESCO M; RUBINSTEIN M; VOLKOW ND; THANOS PK
Dopamine D4 receptors modulate brain metabolic activity in the prefrontal cortex and cerebellum at rest and in response to methylphenidate
EUROPEAN JOURNAL OF NEUROSCIENCE; Año: 2010 vol. 32 p. 668 - 676
THANOS P; BERMEO C; RUBINSTEIN M; SUCHLAND K; WANG G; GRANDY DK; WOLKOW ND
Conditioned place preference and locomotor activity in response to methylphenidate, amphetamine and cocaine in mice lacking dopamine D4 receptors.
JOURNAL OF PSYCHOPHARMACOLOGY; Año: 2010 vol. 24 p. 897 - 904
NEMIROVSKY SI; AVALE ME; BRUNNER D; RUBINSTEIN M
Reward-seeking and discrimination deficits displayed by hypodopaminergic mice are prevented in mice lacking dopamine D4 receptors.
SYNAPSE; Año: 2009 vol. 63 p. 991 - 997
VANINA G. DA ROS; JULIETA A. MALDERA; WILLIAM D. WILLIS; DÉBORA J. COHEN; EUGENIA H. GOULDING; DIEGO M. GELMAN; MARCELO RUBINSTEIN; EDWARD M. EDDY; PATRICIA S. CUASNICU
Impaired sperm fertilizing ability in mice lacking Cysteine-RIch Secretory
DEVELOPMENTAL BIOLOGY; Año: 2008 vol. 320 p. 12 - 18
M. A. KELLY; M. J. LOW; M. RUBINSTEIN; T. J. PHILLIPS
Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice
GENES BRAIN AND BEHAVIOR; Año: 2008 vol. 7 p. 568 - 577
LIJIE GONG; FAYI YAO; KRISTIN HOCKMAN; HENRY H. HENG; GREGORY J. MORTON; KIYOSHI TAKEDA; SHIZUO AKIRA; MALCOLM J. LOW; MARCELO RUBINSTEIN; ROBERT G. MACKENZIE
Signal Transducer and Activator of Transcription-3 Is Required in Hypothalamic Agouti-Related Protein/Neuropeptide Y Neurons for Normal Energy Homeostasis
ENDOCRINOLOGY; Año: 2008 vol. 149 p. 3346 - 3354
WEDEMEYER C; GOUTMAN JD; AVALE ME; FRANCHINI LF; RUBINSTEIN M; CALVO DJ
Functional activation by central monoamines of human dopamine D(4) receptor polymorphic variants coupled to GIRK channels in Xenopus oocytes
EUROPEAN JOURNAL OF PHARMACOLOGY; Año: 2007 vol. 562 p. 165 - 173
BUMASCHNY VF; DE SOUZA FJ; LÓPEZ LEAL R; SANTANGELO AM; LEVI DH; BAETSCHER M; LOW MJ; RUBINSTEIN M
Transcriptional Regulation of Pituitary POMC Is Conserved at the Vertebrate Extremes in Spite of Great Promoter Sequence Divergence
MOLECULAR ENDOCRINOLOGY; Año: 2007 vol. 21 p. 2738 - 2749
SANTANGELO AM; DE SOUZA FJS; FRANCHINI LF; BUMASCHNY VF; LOW MJ; RUBINSTEIN M
Ancient Exaptation of a CORE-SINE Retroposon into a Highly Conserved Mammalian Neuronal Enhancer of the Proopiomelanocortin Gene.
PLOS Genetics; Año: 2007 vol. 3 p. 1813 - 1826
GARCÍA-TORNADU, I; RUBINSTEIN M; GAYLINN BD; HILL D; ARANY E; LOW MJ; DIAZ-TORGA, G; BECU-VILLALOBOS D
GH in the dwarf dopaminergic D2 receptor knockout mouse: somatotrope population, GH release, and responsiveness to GH-releasing factors and somatostatin
EUROPEAN JOURNAL OF ENDOCRINOLOGY; Año: 2006 vol. 190 p. 611 - 619
NOAIN D; AVALE ME; WEDEMEYER C; CALVO DJ; PEPER M; RUBINSTEIN M
Identification of Brain Neurons Expressing the Dopamine D4 Receptor Gene using BAC Transgenic Mice.
EUROPEAN JOURNAL OF NEUROSCIENCE; Año: 2006 vol. 24 p. 2429 - 2438
CRISTINA C; GARCÍA-TORNADÚ I; DÍAZ-TORGA G; RUBINSTEIN M; LOW MJ; BECÚ-VILLALOBOS D
Dopaminergic D2 receptor knockout mouse: an animal model of prolactinoma.
FRONTIERS OF HORMONE RESEARCH.; Año: 2006 vol. 35 p. 50 - 63
DE SOUZA FS, BUMASCHNY VF, LOW MJ, RUBINSTEIN M.
Subfunctionalization of Expression and Peptide Domains Following the Ancient Duplication of the Proopiomelanocortin Gene in Teleost Fishes.
MOLECULAR BIOLOGY AND EVOLUTION; Lugar: Oxford; Año: 2005 vol. 22 p. 2417 - 2427
ELMER GI, PIEPER JO, LEVY J, RUBINSTEIN M, LOW MJ, GRANDY DK, WISE RA
Brain stimulation and morphine reward deficits in dopamine D2 receptor-deficient mice.
PSYCHOPHARMACOLOGY; Lugar: Berlin; Año: 2005 vol. 182 p. 33 - 44
CRISTINA C, DIAZ-TORGA G, BALDI A, GONGORA A, RUBINSTEIN M, LOW MJ, BECU-VILLALOBOS D
Increased pituitary vascular endothelial growth factor-A in dopaminergic D2 receptor knockout female mice.
ENDOCRINOLOGY; Año: 2005 vol. 146 p. 2952 - 2962
DE SOUZA FJS,. SANTANGELO AM, BUMASCHNY VF, AVALE ME, SMART JL, LOW MJ, RUBINSTEIN M
Identification of Neuronal Enhancers of the Proopiomelanocortin Gene by Transgenic Mouse Analysis and Phylogenetic Footprinting.
MOLECULAR AND CELLULAR BIOLOGY; Lugar: Washington; Año: 2005 vol. 25 p. 3076 - 3086
THANOS PK, RIVERA SN, WEAVER K, GRANDY DK, RUBINSTEIN M, UMEGAKI H, WANG GJ, HITZEMANN R, VOLKOW ND
Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: Effects on ethanol drinking.
LIFE SCIENCES; Lugar: Amsterdam; Año: 2005 vol. 77 p. 130 - 139
AVALE ME, FALZONE TL, GELMAN DM, LOW MJ, GRANDY DK, RUBINSTEIN M
The dopamine D4 receptor is essential for hyperactivity and impaired behavioral inhibition in a mouse model of attention deficit/hyperactivity disorder.
MOLECULAR PSYCHIATRY; Lugar: Londres; Año: 2004 vol. 9 p. 718 - 726
AVALE ME, NEMIROVSKY SI, RAISMAN-VOZARI R, RUBINSTEIN M
Elevated Serotonin is Involved in Hyperactivity but not in the Paradoxical Effect of Amphetamine in Mice Neonatally Lesioned with 6-Hydroxydopamine.
JOURNAL OF NEUROSCIENCE RESEARCH; Lugar: New York; Año: 2004 vol. 78 p. 289 - 296
OVERSTREET L, HENTGES S, BUMASCHNY V, SOUZA FJ, SMART J, SANTANGELO A, LOW M, WESTBROOK G, RUBINSTEIN M
A Transgenic Marker for Newly Born Granule Cells in Dentate Gyrus.
JOURNAL OF NEUROSCIENCE; Lugar: Washington; Año: 2004 vol. 23 p. 3251 - 3259
GAN L, FALZONE TL, ZHANG K, RUBINSTEIN M, BALDESSARINI R, TARAZI FI
Enhanced expression of dopamine D1 and glutamate NMDA receptors in dopamine D4 receptor knock-out mice.
JOURNAL OF MOLECULAR NEUROSCIENCE : MN.; Lugar: Oregon; Año: 2004 vol. 22 p. 167 - 178
NARAYANAN S, LAM H, CHRISTIAN L, LEVINE MS, GRANDY D, RUBINSTEIN M, MAIDMENT NT
Endogenous opioids mediate basal hedonic tome independent of D-1 or D-2 receptor activation.
NEUROSCIENCE; Lugar: Amsterdam; Año: 2004 vol. 124 p. 241 - 246
TOMIYAMA K, MCNAMARA FN, CLIFFORD JJ, KINSELLA A, DRAGO J, FUCHS S, GRANDY DK, LOW MJ, RUBINSTEIN M, TIGHE O, CROKE DT, KOSHIKAWA N, WADDINGTON JL.
Comparative phenotypic resolution of spontaneous, D2-like and D1-like agonist-induced orofacial movement topographies in congenic mutants with dopamine D2 vs. D3 receptor "knockout"
SYNAPSE; Lugar: New York; Año: 2004 vol. 51 p. 71 - 81
FRANCHINI LF, RUBINSTEIN M, VIVAS L
Reduced sodium appetite and increased oxytocin gene expression in mutant mice lacking B-endorphin.
NEUROSCIENCE; Lugar: Amsterdam; Año: 2003 vol. 121 p. 875 - 881
KATZ JL, CHAUSMER AL, ELMER GI, RUBINSTEIN M, LOW MJ, GRANDY DK.
Cocaine-induced locomotor activity and cocaine discrimination in dopamine D(4) receptor mutant mice.
PSYCHOPHARMACOLOGY; Lugar: Berlin; Año: 2003 vol. 170 p. 108 - 114
GELMAN DM, NOAÍN DC, AVALE ME, OTERO V,. LOW MJ, RUBINSTEIN M
Transgenic Mice Engineered to Target Cre/LoxP-Mediated DNA Recombination into Catecholaminergic Neurons.
GENESIS (NEW YORK, N.Y. : 2000); Lugar: New York; Año: 2003 vol. 36 p. 196 - 202
LOW MJ, HAYWARD MD, APPLEYARD SM, RUBINSTEIN M.
State-dependent modulation of feeding behavior by proopiomelanocortin-derived beta-endorphin.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES.; Lugar: Oxford; Año: 2003 vol. 994 p. 192 - 201
HEISLER LK, COWLEY MA, KISHI T, TECOTT LH, FAN W, LOW MJ, SMART JL, RUBINSTEIN M, TATRO JB, ZIGMAN JM, CONE RD, ELMQUIST JK.
Central serotonin and melanocortin pathways regulating energy homeostasis.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES.; Lugar: Oxford; Año: 2003 vol. 994 p. 169 - 174
APPLEYARD SM, HAYWARD M, YOUNG JI, BUTLER AA, CONE RD, RUBINSTEIN M, LOW MJ.
A Role for the Endogenous Opioid beta-Endorphin in Energy Homeostasis.
ENDOCRINOLOGY; Año: 2003 vol. 144 p. 1753 - 1760
IBRAHIM N, BOSCH MA, SMART JL, QIU J, RUBINSTEIN M, RONNEKLEIV OK, LOW MJ, KELLY MJ.
Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels.
ENDOCRINOLOGY; Año: 2003 vol. 144 p. 1331 - 1340
THANOS PK, TAINTOR NB, ALEXOFF D, VASKA P, LOGAN J, GRANDY DK, FANG Y, LEE JH, FOWLER JS, RUBINSTEIN M, VOLKOW ND
In vivo comparative imaging of dopamine D2 knockout and wild-type mice with (11)C-raclopride and microPET.
JOURNAL OF NUCLEAR MEDICINE; Lugar: Reston, VA ; Doi: 10.2967/jnumed.110.083246; Año: 2002 vol. 43 p. 1570 - 1577
CHAUSMER AL, ELMER GI, RUBINSTEIN M, LOW MJ, GRANDY DK, KATZ JL
Cocaine-induced locomotor activity and cocaine discrimination in dopamine D2 receptor mutant mice.
PSYCHOPHARMACOLOGY; Lugar: Berlin; Año: 2002 vol. 163 p. 54 - 61
REFOJO D, KOVALOVSKY D, YOUNG JI, RUBINSTEIN M, HOLSBOER F, REUL JM, LOW MJ, ARZT E.
Increased splenocyte proliferative response and cytokine production in beta-endorphin-deficient mice.
JOURNAL OF NEUROIMMUNOLOGY; Lugar: Amsterdam; Año: 2002 vol. 131 p. 126 - 134
ELMER G, PIEPER JO, RUBINSTEIN M, LOW MJ, GRANDY DK, WISE RA
Failure of Intravenous Morphine to Serve as an Effective Instrumental Reinforcer in Dopamine D2 Receptor Knockout Mice
JOURNAL OF NEUROSCIENCE; Lugar: Washington; Año: 2002 vol. 22 p. 2241 - 2246
RAMIREZ JL, MOUCHANTAF R, KUMAR U, OTERO CORCHON V, RUBINSTEIN M, LOW MJ, PATEL YC
Brain somatostatin receptors are up-regulated in somatostatin-deficient mice.
MOLECULAR ENDOCRINOLOGY; Año: 2002 vol. 16 p. 1951 - 1963
HEISLER LK, COWLEY MA, TECOTT LH, FAN W, LOW MJ, SMART JL, RUBINSTEIN M, TATRO J, HOLSTEGE H, LEE C, CONE R, ELMQUIST J
Activation of Central Melanocortin Pathways by Fenfluramine
SCIENCE; Año: 2002 vol. 297 p. 609 - 611
ENSINCK JW, BASKIN DG, VAHL TP, VOGEL RE, LASCHANSKY EC, FRANCIS BH, HOFFMAN RC, KRAKOVER JD, STAMM MR, LOW MJ, RUBINSTEIN M, OTERO-CORCHON V, D'ALESSIO DA
Thrittene, homologous with somatostatin-28((1-13)), is a novel Peptide in Mammalian gut and circulation.
ENDOCRINOLOGY; Año: 2002 vol. 143 p. 2599 - 2609
NIR I, HARRISON JM, HAQUE R, LOW MJ, GRANDY DK, RUBINSTEIN M, IUVONE PM
Dysfunctional light-evoked regulation of cAMP in photoreceptors and abnormal retinal adaptation in mice lacking dopamine D4 receptors.
JOURNAL OF NEUROSCIENCE; Lugar: Washington; Año: 2002 vol. 22 p. 2063 - 2073
DÍAZ-TORGA G, FEIERSTEIN C, LIBERTUN C, GELMAN D, KELLY MA, LOW MJ, RUBINSTEIN M, BECÚ-VILLALOBOS D
Disruption of the D2 dopamine receptor alters GH and IGF-I secretion and causes dwarfism in male mice
ENDOCRINOLOGY; Año: 2002 vol. 143 p. 1270 - 1279
FALZONE TL, GELMAN DG, YOUNG JI, GRANDY DK, LOW MJ, RUBINSTEIN M
Absence of dopamine D4 receptors results in enhanced reactivity to unconditioned, but not conditioned, fear
EUROPEAN JOURNAL OF NEUROSCIENCE; Lugar: Londres; Año: 2002 vol. 15 p. 158 - 164
BUCKMASTER PS, OTERO-CORCHÓN V , RUBINSTEIN M , LOW MJ
Heightened seizure severity in somatostatin knockout mice.
EPILEPSY RESEARCH; Lugar: Amsterdam; Año: 2002 vol. 48 p. 43 - 56
COWLEY MA, SMART JL, RUBINSTEIN M, CERDÁN MG, DIANO S, HORVATH TL, CONE RD, LOW MJ
Leptin activates anorexigenic POMC neurons through a neural network in arcuate nucleus.
NATURE; Lugar: Londres; Año: 2001 vol. 441 p. 480 - 484
FALZONE TL, AVALE ME, GELMAN DM, RUBINSTEIN M
Normal Spatial Learning and Improved Spatial Working Memory in Mice (Mus musculus) Lacking Dopamine D4 Receptors.
International Journal of Comparative Psychology; Lugar: Berlin; Año: 2001 vol. 14 p. 151 - 160
LI XX, BEK M, ASICO LD, YANG Z, GRANDY DK, GOLDSTEIN DS, RUBINSTEIN M, EISNER GM, JOSE PA
Adrenergic and endothelin B receptor-dependent hypertension in dopamine receptor type-2 knockout mice
JOURNAL OF HYPERTENSION; Lugar: Philadelphia; Año: 2001 vol. 38 p. 303 - 308
CLIFFORD JJ, KINSELLA A, TIGHE O, RUBINSTEIN M, GRANDY DK, LOW MJ, CROKE DT, WADDINGTON JL
Comparative, topographically-based evaluation of behavioural phenotype and specification of D1-like:D2 interactions in a line of incipient congenic mice with D2 dopamine receptor ?knockout?.
NEUROPSYCHOPHARMACOLOGY; Lugar: Londres; Año: 2001 vol. 25 p. 527 - 536
LOW MJ, OTERO-CORCHON V, PARLOW AF, RAMIREZ JL, KUMAR U, PATEL YC RUBINSTEIN M
Somatostatin is required for masculinization of growth hormone?regulated hepatic gene expression but not of somatic growth.
JOURNAL OF CLINICAL INVESTIGATION; Lugar: Ann Arbor, Michigan; Año: 2001 vol. 107 p. 1571 - 1580
RUBINSTEIN M, CEPEDA C, HURST RS, ALTEMUS KL, ARIANO MA, FALZONE TL, KOZELL LB, MESHUL CK, BUNZOW JR, LOWMJ, LEVINE MS, GRANDY DK
Dopamine D4 Receptor-Deficient Mice Display Cortical Hyperexcitability.
JOURNAL OF NEUROSCIENCE; Lugar: Washington; Año: 2001 vol. 21 p. 3756 - 3763
DOCKSTADER CL, RUBINSTEIN M, GRANDY DK, LOW MJ, VAN DER KOOY D
The D2 receptor is critical in mediating opiate motivation only in opiate-dependent and withdrawn mice
EUROPEAN JOURNAL OF NEUROSCIENCE; Lugar: Londres; Año: 2001 vol. 13 p. 995 - 1001
CEPEDA C, HURST RS, ALTEMUS KL, FLORES-HERNÁNDEZ J, CALVERT C, JOKEL ES, GRANDY DK, LOW MJ, RUBINSTEIN M, ARIANO MA, LEVINE, MS
Facilitated glutamatergic transmission in the striatum of D2 dopamine receptor deficient-mice.
JOURNAL OF NEUROPHYSIOLOGY; Lugar: Bethesda; Año: 2001 vol. 85 p. 659 - 670
KHAN ZU, KOULEN P, RUBINSTEIN M, GRANDY DK, GOLDMAN-RAKIC PS
An astroglia-linked dopamine D2-receptor action in prefrontal cortex.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2001 vol. 98 p. 1964 - 1969
CHEN J-F, MORATALLA R, IMPAGNATIELLO F, GRANDY DK, CUELLAR B, RUBINSTEIN M, BEILSTEIN MA, HACKETT E, FINK JS, LOW MJ, ONGINI E, SCHWARZSCHILD MA
The Role of the D2 Dopamine Receptor in A2A Adenosine Receptor-Mediated Behavioral and Cellular Responses as Revealed by A2A and D2 Receptor Knockout Mice.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2001 vol. 98 p. 1970 - 1975
MOGIL JS, GRISEL JE, HAYWARD MD, BALES JR, RUBINSTEIN M, BELKNAP JK, LOW MJ
Disparate spinal and supraspinal opioid antiniciceptive responses in -endorphin-deficient mutant mice.
NEUROSCIENCE; Lugar: Amsterdam; Año: 2000 vol. 101 p. 709 - 717
CUNNINGHAM CL, HOWARD MA, GILL SJ, RUBINSTEIN M, LOW MJ, GRANDY DK
Ethanol Conditioned Place Preference is Reduced in Dopamine D2 Receptor Deficient Mice.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; Lugar: Amsterdam; Año: 2000 vol. 67 p. 693 - 699
RISINGER FO, FREEMAN PA, RUBINSTEIN M, LOW MJ, GRANDY DK
Lack of operant ethanol self-administration in dopamine D2 receptor knockout mice.
PSYCHOPHARMACOLOGY; Lugar: Berlin; Año: 2000 vol. 152 p. 343 - 350
MURER MG, DZIEWCZAPOLSKI G, SALIN P, VILA M, TSENG KY, RUBERG M, RUBINSTEIN M, KELLY MA, GRANDY DK, LOW MJ, HIRSCH E, RAISMAN-VOZARI R, GERSHANIK O (
The indirect basal ganglia pathway in dopamine D2 receptor-deficient mice.
NEUROSCIENCE; Lugar: Amsterdam; Año: 2000 vol. 99 p. 643 - 650
TSENG KY, ROUBERT C, DO L, RUBINSTEIN M, KELLY MA, GRANDY DK, LOW MJ, GERSHANIK OS, MURER MG, GIROS B, RAISMAN-VOZARI R
Selective increase of Nurr1 mRNA expression in mesencephalic dopaminergic neurons of D2 dopamine receptor-deficient mice
MOLECULAR BRAIN RESEARCH; Lugar: Amsterdam; Año: 2000 vol. 80 p. 1 - 6
ZAHNISER NR, SIMOSKY JK, MAYFIELD RD, NEGRI CA, HANANIA TG, LARSON GA, KELLY MA, RUBINSTEIN M, GRANDY DK, LOW MJ, FREDHOLM BB
Functional Uncoupling of Adenosine A2A Receptors and Reduced Response to Caffeine in Dopamine D2 Receptor-Deficient Mice.
JOURNAL OF NEUROSCIENCE; Lugar: Washington; Año: 2000 vol. 20 p. 5949 - 5957
DEFAGOT MC, FALZONE TL, LOW MJ, GRANDY DK, RUBINSTEIN M AND ANTONELLI M.
Quantitative analysis of the dopamine D4 receptor in the mouse brain.
JOURNAL OF NEUROSCIENCE RESEARCH; Lugar: New York; Año: 2000 vol. 59 p. 202 - 208
MENALLED LB, DZIEWCZAPOLSKI G, GARCÍA MC, RUBINSTEIN M, GERSHANIK OS
D3 receptor knockdown through antisense oligonucleotide administration supports its inhibitory role in locomotion.
NEUROREPORT; Lugar: Philadelphia; Año: 1999 vol. 10 p. 3131 - 3136
GRISEL JE, MOGIL JS, GRAHAME NJ, RUBINSTEIN M, BELKNAP JK, CRABBE JC, LOW MJ
Ethanol self-administration is increased in mutant mice with decreased ß-endorphin expression.
BRAIN RESEARCH; Lugar: Amsterdam; Año: 1999 vol. 835 p. 62 - 67
RALPH RJ, VARTY GB, KELLY MA, WANG Y-M, CARON MG, RUBINSTEIN M, GRANDY DK, LOW MJ, GEYER MA
The dopamine D2, but not D3 or D4 receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice.
JOURNAL OF NEUROSCIENCE; Lugar: Washington; Año: 1999 vol. 19 p. 4627 - 4633
WILKE RA, LUPARDUS PJ, GRANDY DK, RUBINSTEIN M, LOW MJ, JACKSON MB
Potassium chanel modulation in rodent neurohypophysial nerve terminals by sigma receptors and not by dopamine receptors.
THE JOURNAL OF PHYSIOLOGY; Lugar: Londres; Año: 1999 vol. 517 p. 391 - 406
DICKINSON SD, SABETI J, LARSON GA, GIARDINA K, RUBINSTEIN M, KELLY MA, GRANDY DK, LOW MJ, GERHARDT GA, ZAHNISER NR
Dopamine D2 receptor-deficient mice exhibit decreased dopamine transporter function but no changes in dopamine release in dorsal striatum.
JOURNAL OF NEUROCHEMISTRY; Lugar: Londres; Año: 1999 vol. 72 p. 148 - 156
YOUNG JI, OTERO V, CERDÁN MG, FALZONE TL, CHAN E-C, LOW MJ, RUBINSTEIN M
Authentic Cell-Specific and Developmentally Regulated Expression of Proopiomelanocortin Genomic Fragments in Hypothalamic and Hindbrain Neurons of Transgenic Mice
JOURNAL OF NEUROSCIENCE; Lugar: Washington; Año: 1998 vol. 18 p. 6631 - 6640
PHILLIPS TJ, BROWN KJ, BURKHART-KASCH S, WENGER CD, KELLY MA, RUBINSTEIN M, GRANDY DK, LOW MJ
Alcohol preference and sensitivity are markedly reduced in mice lacking dopamine D2 receptors.
NATURE NEUROSCIENCE.; Lugar: Londres; Año: 1998 vol. 1 p. 610 - 615
LOW MJ, KELLY MA, RUBINSTEIN M, GRANDY DK
Single genes and complex phenotypes.
MOLECULAR PSYCHIATRY; Lugar: Londres; Año: 1998 vol. 3 p. 375 - 377
KELLY MA, RUBINSTEIN M, PHILLIPS TJ, LESSOV CN, BURKHART-KASCH S, ZHANG G, BUNZOW J, FANG Y, GERHARDT GA, GRANDY DK, LOW MJ
Locomotor activity in D2 dopamine receptor deficient mice is determined by gene dosage, genetic background and developmental adaptations.
JOURNAL OF NEUROSCIENCE; Lugar: Washington; Año: 1998 vol. 18 p. 3010 - 3020
DZIEWCZAPOLSKI G, MENALLED LB, GARCÍA MC, MORA MA, GERSHANIK OS, RUBINSTEIN M
Opposite roles of D1 and D5 dopamine receptors in locomotion revealed by selective antisense oligonucleotides.
NEUROREPORT; Lugar: Philadelphia; Año: 1998 vol. 9 p. 1 - 5
CERDÁN MG, YOUNG JI, ZINO E, FALZONE TL, OTERO V, TORRES HN, RUBINSTEIN M
Accurate Spatial and Temporal Transgene Expression Driven by a 3.8 Kilobase Promoter of the Bovine ß-casein Gene in the Lactating Mouse Mammary Gland.
MOLECULAR REPRODUCTION AND DEVELOPMENT; Lugar: New York; Año: 1998 vol. 49 p. 236 - 245
RUBINSTEIN M, PHILLIPS TJ, BUNZOW JR, FALZONE TL, DZIEWCZAPOLSKI G, PUGSLEY TA, ZHANG G, FANG Y, LARSON JL, MCDOUGALL JA, CHESTERJA, SAEZ C, GERSHANIK O, LOW MJ, GRANDY DK
Mice Lacking Dopamine D4 Receptors Are Supersensitive to Ethanol, Cocaine and Methamphetamine.
CELL; Lugar: United States; Año: 1997 vol. 90 p. 991 - 1001
KELLY MA*, RUBINSTEIN M*, ASA SL, ZHANG G, SAEZ C, BUNZOW JR, ALLEN RG, HNASKO R, BEN-JONATHAN N, GRANDY DK, LOW MJ
Pituitary lactotroph hyperplasia and chronic hyperprolactinemia in dopamine D2 receptor-deficient mice.
NEURON; Lugar: United States; Año: 1997 vol. 19 p. 103 - 113
DZWIECZAPOLSKI G, MORA M, MENALLED LB, STEFANO FJE, RUBINSTEIN M, GERSHANIK O
Threshold of dopamine content and D1 receptor stimulation necessary for the expression of rotational behavior induced by D2 receptor stimulation under normo and supersensitive conditions.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY; Lugar: Berlin; Año: 1997 vol. 355 p. 30 - 35
RUBINSTEIN M, MOGIL JS, JAPÓN MA, CHAN EC, ALLEN RG, LOW MJ
Absence of Opioid Stress-Induced Analgesia in Mice Lacking ß-Endorphin by Targeted Mutagenesis.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 1996 vol. 93 p. 3995 - 4000
JAPÓN MA, RUBINSTEIN M, LOW MJ
In situ hybridizarion analysis of anterior pituitary hormone gene expression during fetal mouse development.
THE JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY : OFFICIAL JOURNAL OF THE HISTOCHEMISTRY SOCIETY.; Año: 1994 vol. 42 p. 1117 - 1125
LOW MJ, LIU B, HAMMER GD, RUBINSTEIN M, ALLEN RG
Posttranslational processing of proopiomelanocortin in a transplantable mouse melanotropic tumor
JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda, Maryland; Año: 1993 vol. 268 p. 24967 - 24975
RUBINSTEIN M, JAPÓN MA, LOW MJ
Introduction of a point mutation into the genome by homologous recombination in embryonic stem cells using a replacement type vector with a selectable marker.
NUCLEIC ACIDS RESEARCH; Lugar: Oxford; Año: 1993 vol. 21 p. 2613 - 2617
RUBINSTEIN M, MORTRUD M, LIU B, LOW MJ
Rat and mouse proopiomelanocortin gene sequences target tissue-specific expression to the pituitary gland but not to the hypothalamus of transgenic mice.
NEUROENDOCRINOLOGY; Lugar: Basel; Año: 1993 vol. 58 p. 373 - 380
LIU B, HAMMER GD, RUBINSTEIN M, MORTRUD M, LOW MJ
Identification of DNA elements cooperatively activating proopiomelanocortin gene expression in the pituitary gland of transgenic mice.
MOLECULAR AND CELLULAR BIOLOGY; Lugar: Washington; Año: 1992 vol. 9 p. 3978 - 3990
RUBINSTEIN M, LIU B, GOODMAN RH, LOW MJ
Targeted expression of somatostatin in vasopressinergic magnocellular hypothalamic neurons of transgenic mice.
MOLECULAR AND CELLULAR NEUROSCIENCES.; Lugar: Amsterdam; Año: 1992 vol. 9 p. 3978 - 3990
RUBINSTEIN M, MUSCHIETTI JP, GERSHANIK O, FLAWIÁ MM, STEFANO FJE
Adaptative mechanisms of striatal D1 and D2 dopamine receptors in response to a prolonged reserpine treatment in mice
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS; Lugar: Baltimore; Año: 1990 vol. 252 p. 810 - 816
BOLIOLO B, CASTELLO ME, JERUSALINSKI D, RUBINSTEIN M, MEDINA J, DAJAS F
Neurochemical and behavioral correlates of unilateral striatal acetylcholinesterase inhibition by fasciculin in rats
BRAIN RESEARCH; Lugar: Amsterdam; Año: 1989 vol. 44 p. 337 - 346
RUBINSTEIN M, SCHINDER AF, GERSHANIK O, STEFANO FJE
Positive interaction between alpha-1 adrenergic and dopamine-2 receptors in locomotor activity of normo and supersensitive mice
LIFE SCIENCES; Lugar: Amsterdam; Año: 1988 vol. 44 p. 337 - 346
RUBINSTEIN M, GERSHANIK O, STEFANO FJE
Different roles of D-1 and D-2 dopamine receptors involved in locomotor activity of supersensitive mice.
EUROPEAN JOURNAL OF PHARMACOLOGY; Lugar: Amsterdam; Año: 1988 vol. 148 p. 419 - 426
RUBINSTEIN M, GERSHANIK O, STEFANO FJE
Postsynaptic bimodal effect of sulpiride on locomotor activity induced by pergolide in catecholamine-depleted mice.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY; Lugar: Berlin; Año: 1988 vol. 337 p. 115 - 117