IMPERIALE, BELÉN R.; MANCINO, MARÍA B.; MOYANO, ROBERTO D.; DE LA BARRERA, SILVIA; MORCILLO, NORA S.

In vitro and ex vivo activity of the fluoroquinolone DC-159a against mycobacteria

JOURNAL OF ANTIBIOTICS; Año: 2024

IMPERIALE, BELÉN R.; GAMBERALE, ANA; YOKOBORI, NOEMÍ; GARCÍA, ANA; BARTOLETTI, BRUNO; AIDAR, OMAR; LÓPEZ, BEATRIZ; CRUZ, VICTOR; GONZÁLEZ MONTANER, PABLO; PALMERO, DOMINGO J.; DE LA BARRERA, SILVIA

Transforming growth factor-β, Interleukin-23 and interleukin-1β modulate TH22 response during active multidrug-resistant tuberculosis

IMMUNOLOGY; Lugar: Londres; Año: 2023

IMPERIALE BELÉN; GARCÍA ANA; MINOTTI ALAN; GONZALEZ MONTANER PABLO; MORACHO LUCÍA; MORCILLO NORA; PALMERO DOMINGO; SASIAIN MARÍA DEL CARMEN; DE LA BARRERA SILVIA

Th22 response induced by Mycobacterium tuberculosis strains is closely related to severity of pulmonary lesions and bacillary load in patients with multidrug-resistant tuberculosis

CLINICAL AND EXPERIMENTAL IMMUNOLOGY; Lugar: Londres; Año: 2021 vol. 203 p. 267 - 280

BEI, JINLONG; BIGI, MARÍA MERCEDES; LIMA, ANALÍA; ZHANG, QI; BLANCO, FEDERICO CARLOS; LOPEZ, BEATRIZ; YU, TING; WANG, ZHILIN; DAI, ZHANGYAN; CHEN, ZHUANG; CATALDI, ANGEL ADRIAN; SASIAIN, MARÍA DEL CARMEN; RITACCO, VIVIANA; DE LA BARRERA, SILVIA; SORIA, MARCELO ABEL; DURÁN, ROSARIO; BIGI, FABIANA

A Phenotypic Characterization of Two Isolates of a Multidrug-Resistant Outbreak Strain of Mycobacterium tuberculosis with Opposite Epidemiological Fitness

BioMed Research International; Año: 2020 vol. 2020 p. 1 - 9

RIVADENEYRA, LEONARDO; CHARÓ, NANCY; KVIATCOVSKY, DENISE; DE LA BARRERA, SILVIA; GÓMEZ, RICARDO MARTÍN; SCHATTNER, MIRTA

Role of neutrophils in CVB3 infection and viral myocarditis

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY; Año: 2018 vol. 125 p. 149 - 161

BIGI MM; LOPEZ B; BLANCO FC; SASIAIN MD; DE LA BARRERA S; MARTI MA; SOSA JE; FERNÁNDEZ DO PORTO DA; RITACCO V; BIGI F; SORIA MA

Single nucleotide polymorphisms may explain the contrasting phenotypes of two variants of a multidrug-resistant Mycobacterium tuberculosis strain

Tuberculosis (Edinb); Lugar: ESCOCIA; Año: 2017 vol. 103 p. 28 - 36

ROLANDELLI A; HERNÁNDEZ DEL PINO RE; PELLEGRINI JM; TAETOSIAN NL; AMINAO NO; DE LA BARRERA S; CASCO N; GUTIÉRREZ M; PALMERO DOMINGO; GARCÍA V

The IL-17A rs2275913 single nucleotide polymorphism is associated with protection to tuberculosis but related to higher disease severity in Argentina

Scientific Reports; Año: 2017

BASILE JI; KVIATCOVSKY D; ROMERO M; BALBOA L; MONTESERIN J; RITACCO V; LOPEZ B; SABIO Y GARCÍA C; GARCÍA A; VESCOVO M; GONZALEZ MONTANER P; PALMERO DOMINGO; SASIAIN MARÍA DEL CARMEM; DE LA BARRERA SILVIA

Mycobacterium tuberculosis multi-drug-resistant strain M induces IL-17+ IFNγ- CD4+ T cell expansion through an IL-23 and TGF-β-dependent mechanism in patients with MDR-TB tuberculosis.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY; Lugar: Londres; Año: 2017 vol. 187 p. 160 - 173

KVIATCOVSKY, DENISE; RIVADENEYRA, LEONARDO; BALBOA, LUCIANA; YOKOBORI, NOEMÍ; LÓPEZ, BEATRIZ; RITACCO, VIVIANA; SCHATTNER, MIRTA; SASIAIN, MARÍA DEL CARMEN; DE LA BARRERA, SILVIA

Mycobacterium tuberculosis Multidrug-Resistant Strain M Induces Low IL-8 and Inhibits TNF- α Secretion by Bronchial Epithelial Cells Altering Neutrophil Effector Functions

MEDIATORS OF INFLAMMATION; Año: 2017 vol. 2017 p. 1 - 13

SABIO Y GARCÍA CARMEN; YOKOBORI NOEMÍ; BASILE JUAN; BALBOA LUCIANA; GONZALEZ ALEJANDRA; LOPEZ BEATRIZ; RITACCO VIVIANA; DE LA BARRERA SILVIA; SASIAIN MARÍA DEL CARMEN

C5aR contributes to the weak Th1 profile induced by an outbreak strain of Mycobacterium tuberculosis

Tuberculosis (Edinb); Lugar: ESCOCIA; Año: 2017 vol. 103 p. 16 - 27

BALBOA LUCIANA; KVIATCOVSKY DENISE; SCHIERLOH PABLO; GARCÍA MARINA; DE LA BARRERA SILVIA; SASIAIN MARÍA DEL CARMEM

Monocyte-derived dendritic cells early exposed to Mycobacterium tuberculosis induce an enhanced T helper 17 response and transfer mycobacterial antigens

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (PRINT); Año: 2016

GEFFNER LAURA; BASILE JUAN; YOKOBORI NOEMÍ; KVIATCOVSKY DENISE; SABIO Y GARCÍA CARMEN; RITACCO VIVIANA; LOPEZ BEATRIZ; SASIAIN MARÍA DEL CARMEM; DE LA BARRERA SILVIA

Mycobacterium tuberculosis Multidrug Resistant Strain M Induces an Altered Activation of Cytotoxic CD8+ T Cells

PLOS ONE; Lugar: San Francisco; Año: 2014 vol. 9 p. 1 - 13

GEFFNER LAURA; BASILE JUAN; YOKOBORI NOEMÍ; SABIO Y GARCÍA CARMEN; MUSELLA ROSA; CASTAGNINO J; SASIAIN MARÍA DEL CARMEM; DE LA BARRERA SILVIA

CD4+CD25highforkhead box protein 3+ regulatory T lymphocytes suppress interferon-γ and CD107 expression in CD4+ and CD8+ T cells from tuberculous pleural effusions

CLINICAL AND EXPERIMENTAL IMMUNOLOGY; Lugar: Londres; Año: 2014 vol. 175 p. 235 - 245

YOKOBORI NOEMÍ; SABIO Y GARCÍA CARMEN; GEFFNER LAURA; SCHIERLOH PABLO; LOPEZ BEATRIZ; RITACCO VIVIANA; BARRERA LUCIA; DE LA BARRERA SILVIA; SASIAIN MARÍA DEL CARMEN

Differential induction of macrophage cell death by antigens of a clustered and a non-clustered multidrug-resistant Mycobacterium tuberculosis strain from Haarlem family

FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY; Lugar: Londres; Año: 2012

ROMERO MERCEDES; BALBOA L; BASILE JUAN; LOPEZ BEATRIZ; RITACCO VIVIANA; DE LA BARRERA SILVIA; SASIAIN MARÍA DEL CARMEN; BARRERA LUCIA; ALEMÁN MERCEDES

Clinical Isolates of Mycobacterium tuberculosis Differ in Their Ability to Induce Respiratory Burst and Apoptosis in Neutrophils as a PossibleMechanism of Immune Escape

CLINICAL AND DEVELOPMENTAL IMMUNOLOGY; Lugar: New York; Año: 2012 vol. 2012 p. 1 - 11

BALBOA LUCIANA; ROMERO MERCEDES; BASILE J; SABIO Y GARCíA C; SCHIERLOH PABLO; YOKOBORI NOEMí; GEFFNER LAURA; MUSELLA ROSA; CASTAGNINO J; ABBATE, EDUARDO; DE LA BARRERA SILVIA; SASIAIN MARíA DEL CARMEM; ALEMáN MERCEDES

Paradoxical role of CD16+CCR2+CCR5+ monocytes in tuberculosis: efficient APC in pleural effusion but also mark disease severity in blood.

JOURNAL OF LEUKOCYTE BIOLOGY; Año: 2011 vol. 90 p. 69 - 75

BASILE J; GEFFNER LAURA; ROMERO MERCEDES; BALBOA LUCIANA; SABIO Y GARCÍA C; RITACCO VIVIANA; GARCÍA ANA; CUFFRÉ M; ABBATE EDUARDO; LOPEZ BEATRIZ; BARRERA LUCIA; AMBROGGI M; ALEMÁN MERCEDES; SASIAIN MARÍA DEL CARMEM; DE LA BARRERA SILVIA

Outbreaks of M.tuberculosis MDR strains induce high IL-17 T cell response in patients with MDR

JOURNAL OF INFECTIOUS DISEASES; Año: 2011 vol. 204 p. 1054 - 1064

BALBOA LUCIANA; ROMERO MERCEDES; YOKOBORI NOEMÍ; SCHIERLOH PABLO; GEFFNER LAURA; BASILE, J; MUSELLA ROSA; ABBATE EDUARDO; DE LA BARRERA SILVIA; SASIAIN MARÍA DEL CARMEM; ALEMÁN MERCEDES

Mycobacterium tuberculosis impairs dendritic cell response by altering CD1b, DC-SIGN and MR profile.

IMMUNOLOGY AND CELL BIOLOGY; Año: 2010 vol. 88 p. 716 - 726

ALVAREZ IVANA BELÉN; V. PASQUINELLI; JURADO JAVIER; ABBATE, EDUARDO; MUSELLA ROSA; DE LA BARRERA SILVIA; GARCÍA VERÓNICA

Role played by the programmed death-1-programmed death ligand pathway during innate immunity against Mycobacterium tuberculosis

JOURNAL OF INFECTIOUS DISEASES; Año: 2010 vol. 202 p. 524 - 532

YOKOBORI NOEMÍ; SCHIERLOH PABLO; GEFFNER LAURA; BALBOA LUCIANA; ROMERO MERCEDES; MUSELLA ROSA; CASTAGNINO J; DE STEFANO G; ALEMÁN MERCEDES; DE LA BARRERA SILVIA; ABBATE EDUARDO; SASIAIN MARÍA DEL CARMEM

CD3 expression distinguishes two gammadeltaT cell receptor subsets with different phenotype and effector function in tuberculous pleurisy.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY; Año: 2009 vol. 157 p. 385 - 394

SCHIERLOH PABLO; YOKOBORI NOEMÍ; GEFFNER LAURA; BALBOA LUCIANA; ROMERO MERCEDES; MUSELLA ROSA; ALEMÁN MERCEDES; CASTAGNINO J; BASILE, J; DE LA BARRERA SILVIA; ABBATE EDUARDO; SASIAIN MARÍA DEL CARMEM

NK cells from tuberculous pleurisy express high ICAM-1 levels and exert stimulatory effect on local T cells.

EUROPEAN JOURNAL OF IMMUNOLOGY; Año: 2009 vol. 39 p. 2450 - 2458

GEFFNER LAURA; YOKOBORI NOEMÍ; BASILE, J; SCHIERLOH PABLO; BALBOA LUCIANA; ROMERO MERCEDES; RITACCO VIVIANA; VESCOVO MARISA; GONZALEZ MONTANER P; LOPEZ BEATRIZ; BARRERA LUCIA; ALEMÁN MERCEDES; ABBATE EDUARDO; SASIAIN MARÍA DEL CARMEM; DE LA BARRERA SILVIA

Patients with multidrug-resistant tuberculosis display impaired Th1 responses and enhanced regulatory T-cell levels in response to an outbreak of multidrug-resistant Mycobacterium tuberculosis M and Ra strains.

INFECTION AND IMMUNITY; Año: 2009 vol. 77 p. 5025 - 5034

ALEMÁN MERCEDES; DE LA BARRERA SILVIA; SCHIERLOH PABLO; YOKOBORI NOEMÍ; M. BALDINI; MUSELLA ROSA; ABBATE EDUARDO; SASIAIN MARÍA DEL CARMEM

Spontaneous or Mycobacterium tuberculosis-induced apoptotic neutrophils exert opposite effects on the dendritic cell-mediated immune response.

EUROPEAN JOURNAL OF IMMUNOLOGY; Año: 2007 vol. 37 p. 1524 - 1537

CASSATARO J; VELIKOVSKY CA; BRUNO L; ESTEIN SM; DE LA BARRERA SILVIA; BOWDEN R; FOSSATI CA; GIAMBARTOLOMEI GH

Improved immunogenicity of a vaccination regimen combining a DNA vaccine encoding Brucella melitensis outer membrane protein 31 (Omp31) and recombinant Omp31 boosting.

Clinical and Vaccine Immunology; Año: 2007 vol. 14 p. 869 - 874

FINIASZ, MARTA; FRANCO, MARÍA CLARA; DE LA BARRERA, SILVIA; RUTIZKY LAURA; PIZZARIELLO, GRACIELA; SASIAIN MARÍA DEL CARMEM; RENAULD JC; VAN SNICK J; FINK S

IL-9 promotes anti-Mycobacterium leprae cytotoxicity: involvement of IFNgamma

CLINICAL AND EXPERIMENTAL IMMUNOLOGY; Año: 2007 vol. 147 p. 139 - 147

CASSATARO J; PASQUEVICH KA; ESTEIN SM; LAPLAGNE DA; VELIKOVSKY CA; DE LA BARRERA SILVIA; BOWDEN R; FOSSATI CA; GIAMBARTOLOMEI GH; GOLDBAUM F

A recombinant subunit vaccine based on the insertion of 27 amino acids from Omp31 to the N-terminus of BLS induced a similar degree of protection against B. ovis than Rev.1 vaccination.

VACCINE; Lugar: Amsterdam; Año: 2007 vol. 25 p. 4437 - 4446

SCHIERLOH PABLO; YOKOBORI NOEMÍ; ALEMÁN MERCEDES; LANDONI VERÓNICA; GEFFNER LAURA; MUSELLA ROSA; CASTAGNINO J; M. BALDINI; ABBATE EDUARDO; DE LA BARRERA SILVIA; SASIAIN MARÍA DEL CARMEM

Mycobacterium tuberculosis-induced gamma interferon production by natural killer cells requires cross talk with antigen-presenting cells involving Toll-like receptors 2 and 4 and the mannose receptor in tuberculous pleurisy

INFECTION AND IMMUNITY; Año: 2007 vol. 75 p. 5325 - 5337

CASSATARO J; PASQUEVICH KA; ESTEIN SM; LAPLAGNE DA; ZWERDLING A; DE LA BARRERA SILVIA; BOWDEN R; FOSSATI CA; GIAMBARTOLOMEI GH; GOLDBAUM F

A DNA vaccine coding for the chimera BLSOmp31 induced a better degree of protection against B. ovis and a similar degree of protection against B. melitensis than Rev.1 vaccination

VACCINE; Lugar: Amsterdam; Año: 2007 vol. 25 p. 5958 - 5967

DE LA BARRERA SILVIA; ALEMÁN MERCEDES; SASIAIN MARÍA DEL CARMEM

Toll-like receptors in human infectious diseases

CURRENT PHARMACEUTICAL DESIGN.; Año: 2006 vol. 12 p. 4173 - 4184

ALEMAN, MERCEDES; SILVIA SUSANA DE LA BARRERA; P.SCHIERLOH; L. ALVES; N. YOKOBORI; M. BALDINI; ABBATE, EDUARDO; SASIAIN, MARÍA

In tuberculous pleural effusions, activated neutrophils undergo apoptosis and acquire a dendritic cell-like phenotype

Journal of Infectious Diseases; Año: 2005 vol. 192 p. 399 - 409

J. CASSATARO; CA VELIKOVSKY; SILVIA SUSANA DE LA BARRERA; ESTEIN SM; BRUNO L; BOWDEN R; PASQUEVICH KA; FOSSATI CA; GIAMBARTOLOMEI GH

A DNA vaccine coding for the Brucella outer membrane protein 31 confers protection against B. melitensis and B. ovis infection by eliciting a specific cytotoxic response.

Infection and Immunity; Año: 2005 vol. 73 p. 6537 - 6546

SCHIERLOH PABLO; YOKOBORI NOEMÍ; ALEMÁN MERCEDES; MUSELLA ROSA; BEIGIER-BOMPADRE MACARENA; SAAB MATÍAS; ALVES LEANDRO; ABBATE EDUARDO; DE LA BARRERA SILVIA; SASIAIN MARÍA DEL CARMEN

Increased susceptibility to apoptosis of CD56dimCD16+ NK cells induces the

JOURNAL OF IMMUNOLOGY; Lugar: USA; Año: 2005 vol. 175 p. 6852 - 6860

DE LA BARRERA SILVIA; ALEMÁN MERCEDES; SASIAIN MARÍA DEL CARMEN

Toll-like receptors in human infectious diseases.

CURRENT PHARMACEUTICAL DESIGN.; Año: 2005 vol. 12 p. 4173 - 4184

SCHIERLOH PABLO; ALEMÁN MERCEDES; YOKOBORI NOEMÍ; ALVES LEANDRO; ROLDÁN MATÍAS; ABBATE EDUARDO; SASIAIN MARÍA DEL CARMEM; DE LA BARRERA SILVIA

NK cell activity in tuberculosis is associated with impaired CD11a and ICAM-1

IMMUNOLOGY; Lugar: United Kingdom; Año: 2005 vol. 116 p. 541 - 552

SILVIA SUSANA DE LA BARRERA; ALEMAN, MERCEDES; R. MUSELLA; P.SCHIERLOH; V. PASQUINELLI; V. GARCÍA; ABBATE, EDUARDO; SASIAIN, MARÍA

IL-10 down-regulates costimulatory molecules on Mycobacterium tuberculosis-pulsed macrophages and impairs the lytic activity of CD4 and CD8 CTL in tuberculosis patients.

Clinical and Experimental Immunology; Año: 2004 vol. 128 p. 128 - 138

DE LA BARRERA, SILVIA; FINIASZ, MARTA; FINK , SUSANA; ILARREGUI, JUAN; ALEMAN, MERCEDES; OLIVARES, LILIANA; FRANCO, MARÍA CLARA; PIZZARIELLO, GRACIELA; SASIAIN, MARÍA DEL CARMEN; SILVIA SUSANA DE LA BARRERA

NK cells modulate the cytotoxic activity generated by Mycobacterium leprae-hsp65 in leprosy patients. role of IL-18 and IL-13.

Clinical Exp. Immunol. 135: 105-113, 2004.; Lugar: Oxford; Año: 2004 vol. 135 p. 105 - 113

ALEMAN, MERCEDES; P.SCHIERLOH; SILVIA SUSANA DE LA BARRERA; R. MUSELLA; SAAB, MARÍA; M. BALDINI; ABBATE, EDUARDO; SASIAIN, MARÍA

Mycobacterium tuberculosis triggers apoptosis in peripheral neutrophils involving toll-like receptor 2 and p38 mitogen protein kinase in tuberculosis

Infection and Immunity; Año: 2004 vol. 72 p. 5150 - 5158

DE LA BARRERA SILVIA; FINIASZ, MARTA; FRÍAS ANA; ALEMÁN MERCEDES; BARRIONUEVO PAULA; FINK , SUSANA; FRANCO, MARÍA CLARA; ABBATE, EDUARDO; SASIAIN MARÍA DEL CARMEN

Specific lytic activity against mycobacterial antigens is inversely correlated with the severity of tuberculosis.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY; Lugar: Londres; Año: 2003 vol. 132 p. 450 - 461

ALEMÁN MERCEDES; GARCÍA ANA; SAAB, MARÍA; DE LA BARRERA SILVIA; FINIASZ, MARTA; ABBATE, EDUARDO; SASIAIN MARÍA DEL CARMEN

Mycobacterium tuberculosis-induced activation accelerates apoptosis in peripheral blood neutrophils from patients with active tuberculosis.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY; Lugar: New York; Año: 2002 vol. 27 p. 583 - 592

BARRIONUEVO PAULA; BEIGIER-BOMPADRE MACARENA; DE LA BARRERA SILVIA; ALVES-ROSA MARÍA FERNANDA; FERNANDEZ GABRIELA; PALERMO MARINA; ISTURIZ MARTÍN

Immune complexes (IC) down-regulate the basal and interferon-gamma-induced expression of MHC class II on human monocytes.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY; Lugar: Londres; Año: 2001 vol. 125 p. 251 - 257

ALEMÁN MERCEDES; BEIGIER-BOMPADRE MACARENA; BORGHETTI C; DE LA BARRERA SILVIA; ABBATE EDUARDO; ISTURIZ MARTÍN; SASIAIN MARÍA DEL CARMEM

Activation of peripheral blood neutrophils from patients with active advanced tuberculosis.

CLINICAL IMMUNOLOGY; Lugar: Amsterdam; Año: 2001 vol. 100 p. 87 - 95

DE LA BARRERA SILVIA; FINK , SUSANA; FINIASZ, MARTA; ALEMÁN MERCEDES; FARIÑA HELENA; PIZZARIELLO, GRACIELA; SASIAIN MARÍA DEL CARMEM

Lysis of autologous macrophages pulsed with hsp10 from Mycobacterium leprae is associated to the absence of bacilli in leprosy.

IMMUNOLOGY LETTERS; Lugar: Amsterdam; Año: 2001 vol. 76 p. 55 - 62

ALEMÁN MERCEDES; DE LA BARRERA SILVIA; FINK , SUSANA; FINIASZ, MARTA; FARIÑA HELENA; PIZZARIELLO, GRACIELA; SASIAIN MARÍA DEL CARMEM

Interleukin-12 amplifies the M. leprae hsp65-cytotoxic response in the presence of tumour necrosis factor-alpha and interferon-gamma generating CD56+ effector cells: interleukin-4 downregulates this effect.

SCANDINAVIAN JOURNAL OF IMMUNOLOGY; Lugar: Londres; Año: 2000 vol. 51 p. 262 - 270

SASIAIN MARÍA DEL CARMEN; DE LA BARRERA SILVIA; FINK , SUSANA; FINIASZ, MARTA; ALEMÁN MERCEDES; FARIÑA HELENA; PIZZARIELLO, GRACIELA; VALDEZ R

Interferon-gamma (IFN-gamma) and tumour necrosis factor-alpha (TNF-alpha) are necessary in the early stages of induction of CD4 and CD8 cytotoxic T cells by Mycobacterium leprae heat shock protein (hsp) 65 kD.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY; Lugar: Londres; Año: 1998 vol. 114 p. 196 - 203